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CAZyme Information: MGYG000000150_04637
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Hungatella sp005845265 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella; Hungatella sp005845265 | |||||||||||
| CAZyme ID | MGYG000000150_04637 | |||||||||||
| CAZy Family | PL8 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 25587; End: 31157 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| PL8 | 935 | 1230 | 3.4e-77 | 0.9884169884169884 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd01083 | GAG_Lyase | 2.30e-169 | 538 | 1303 | 1 | 693 | Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase. |
| pfam02278 | Lyase_8 | 6.48e-80 | 935 | 1230 | 1 | 252 | Polysaccharide lyase family 8, super-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. |
| pfam08124 | Lyase_8_N | 1.41e-64 | 564 | 894 | 21 | 323 | Polysaccharide lyase family 8, N terminal alpha-helical domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. |
| NF033838 | PspC_subgroup_1 | 3.64e-30 | 1730 | 1854 | 485 | 603 | pneumococcal surface protein PspC, choline-binding form. The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. |
| NF033930 | pneumo_PspA | 4.06e-30 | 1728 | 1854 | 440 | 560 | pneumococcal surface protein A. The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| SET74231.1 | 0.0 | 1 | 1853 | 1 | 1910 |
| ASM70662.1 | 0.0 | 393 | 1363 | 51 | 1015 |
| ASM68536.1 | 2.14e-303 | 417 | 1313 | 11 | 901 |
| AHB61202.1 | 1.01e-144 | 484 | 1358 | 294 | 1093 |
| SQI63227.1 | 7.25e-141 | 428 | 1360 | 271 | 1127 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6F2P_A | 1.14e-106 | 603 | 1351 | 60 | 744 | Structureof Paenibacillus xanthan lyase to 2.6 A resolution [Paenibacillus] |
| 1J0M_A | 1.01e-103 | 536 | 1358 | 1 | 751 | CrystalStructure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1],1J0N_A Crystal Structure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1] |
| 1X1H_A | 1.01e-103 | 536 | 1358 | 1 | 751 | ChainA, xanthan lyase [Bacillus sp. GL1],1X1I_A Chain A, xanthan lyase [Bacillus sp. GL1],1X1J_A Chain A, xanthan lyase [Bacillus sp. GL1] |
| 2E22_A | 1.37e-103 | 536 | 1358 | 1 | 751 | Crystalstructure of xanthan lyase in complex with mannose [Bacillus sp. GL1] |
| 2E24_A | 1.37e-103 | 536 | 1358 | 1 | 751 | ChainA, Xanthan lyase [Bacillus sp. GL1] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q9AQS0 | 6.89e-102 | 528 | 1364 | 20 | 786 | Xanthan lyase OS=Bacillus sp. (strain GL1) OX=84635 GN=xly PE=1 SV=1 |
| Q59801 | 4.01e-61 | 527 | 1316 | 33 | 778 | Hyaluronate lyase OS=Staphylococcus aureus (strain NCTC 8325 / PS 47) OX=93061 GN=hysA PE=3 SV=1 |
| Q54873 | 2.46e-59 | 484 | 1258 | 249 | 947 | Hyaluronate lyase OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=SP_0314 PE=1 SV=2 |
| Q53591 | 1.65e-57 | 495 | 1255 | 215 | 925 | Hyaluronate lyase OS=Streptococcus agalactiae serotype III (strain NEM316) OX=211110 GN=hylB PE=1 SV=2 |
| P0CZ01 | 3.73e-57 | 622 | 1359 | 113 | 795 | Hyaluronate lyase OS=Cutibacterium acnes (strain DSM 16379 / KPA171202) OX=267747 GN=PPA0380 PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000564 | 0.998524 | 0.000357 | 0.000191 | 0.000173 | 0.000158 |
