CAZyme Information: MGYG000000150_05631

Basic Information

• Species: Hungatella sp005845265
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella; Hungatella sp005845265
• CAZyme ID: MGYG000000150_05631
• CAZy Family: GH136
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1869	MGYG000000150_37|CGC1	205481.74	4.396

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000150	7470188	Isolate	United Kingdom	Europe

• Gene Location: Start: 38802; End: 44411 Strand: +

Full Sequence      

MRLKQRTWFRRTIAAVLVAGMTVATGMFTLAAPGNGGKTAGASDWKEIAAVDFSGLESLD
NLKDGWVVSGGSGTAELVEAGESAEGKALKLTRSSDGAVTQLVRSALGIDKSNCSYVSIE
TRLKLGTEKGNKQWSIPYIKDKNGKVAYTVFVSDDANQWSQYKTHVNGTNNQAAGTAVPG
TWQTVRMDINLEKNTFRVSVDGSYVLYDENARSAADSLDTIQFYADSWNRGTVYIQSVKV
MGQQEHKAGTTYYVSSEGNDEAAGTSENTAWKTLGRVNREHFIPGDRILFRCGDEWENET
LFPQGSGSADEKIVLGSYGEGAMPKISTNGKAADAVCLYNQEYWEICGLDISNTVEGFSQ
LSGDGNGDGTPPETNNADRNAADGKLLGEYRGIHIAGRDVASLKGYHLHDLLIHDVTGVV
SWIGDTGLKDAGIVNNAGLDGSKRTGGILIECLKPSGNQPTQFSDIVIEDSEFINNSFCG
ITVKQWNGEGSQYSNNPGWANRNRAGGAPDYYDANWYPHSNIIIQDNYINQGASAYACNG
IYLTSSKDSVIQRNVLEHIGTCGIELYFADNVAVQYNEISDVVKKGGGADDNAIDPDWRV
TNSLIQYNYIHDAGEGFLLCGVHFNSGVIRYNLVQDCGRSYVHYSMGSGYFQIYNNIFYR
SKDGNGTNNFDPWGGGSAAYFNNVFYDGKGQGFNFSGGSNFAYDNNAYYGTAPTSKDKNP
ILLTDDPFEGDAPSLNRKGNFKTGVLLEANGLRPRVDSPLIAAGVDRDPNGYSIDDGLKS
KGSKFNFTSLDKADTNYLGDCINIGRMDYPTFEKTDAEATFDSPKTQTVADQNAPTIGMF
ELSLAPDAVILRGTVTDGLNPVTGAVVEVTSGDKTVEAVTNKSGVYSIVQGLAPGVATIT
VKCEKEDITDTITLEGGKVNQHDVTVPMADMPGSFENVLIEENFEEQTDPDNFGFSHGTK
IENGKLVLTAGSMGNATTAVKTFGPEITGQRGIDMTFDYVCTKGDKQGFEFRDSYGRLLF
AICAAADKNDLRPSVTGGAVDDSKAAAAEEPSWNHIDMNKDTTYTIRVHADFEEKTVSYS
ITEKDGKVAAQEIAIPTEASNLAKMIACNWWVGQPQYIDNFRLTAPEAALDLPLEGKTLY
AFGDSIVAGHQYTKHSFADFIADQEGMILQKYAVNGATIMEAGYSGGQILSQLNSAPDEA
PDYIIFDGGTNDAEYLLNKDSESLGTIVEECDPERFDTDTFAGAFEKTVYEMKKKWPDAQ
LVYVAVHKLGSRDESMQDKLHELELAACAKWEVAVANLYDDSELDTRKEPHKNRYTFNSL
DSNGLPGTNGSGTHPNLAAIEEFYVPAVTGALRRPEVPSSDKEVLTALIEEAEKETEKTD
IYSPEAIEAVKKAIEAAKKTAEKVFATQKEVDDQIKQLKKAMDELKGTETGYYTERIKVT
KKPERTNYEIGDRFDPEGMEVTIYEIASSSNAARSRVLSPEEYEVESESFETAGTKTVTT
VYHGVGSDGQEEAFYDSFTVEVIEALENEVYTTGIKVTRKPNKLMYETGDDFDPAGMKVV
AYEVASASNASRNERTLNPDEYQIRHESFDTDGTKKVTVYYEAENKEGDNEVFTDSFTVT
VTEVWEEYYTTGIEVRKKPDKTVYKTGEDFDPEGMKVVAYERRATASNAERRERVLTEDE
YDLDIPSFGIQGSKTIKVVYEGVDKNGEDKTFKDTFTVKVLGRTVSSNDNDSDSSGSVYI
PDDSITGTWQGGQNEPWKFKKSTGTYATNEWAKINGKWYHFDQDSNMQTGWLSDQNKWYL
LNPDGAMCADTWVLVNGKWYYFNADGSMKCNEWYFYKEDWYYLGRDGDMLVSDITPDGYQ
VDSEGKWIK

Enzyme Prediction     

No EC number prediction in MGYG000000150_05631.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH136	249	808	9.9e-93	0.9857433808553971

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
NF033840	PspC_relate_1	1.95e-23	1753	1869	515	648	PspC-related protein choline-binding protein 1. Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.
NF033930	pneumo_PspA	7.56e-22	1754	1849	489	581	pneumococcal surface protein A. The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.
COG5263	COG5263	3.13e-21	1754	1868	158	313	Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism].
NF033838	PspC_subgroup_1	3.26e-21	1754	1868	572	683	pneumococcal surface protein PspC, choline-binding form. The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
NF033930	pneumo_PspA	5.97e-21	1754	1868	549	660	pneumococcal surface protein A. The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CBK93002.1	0.0	4	1363	3	1332
BBC61707.1	3.88e-107	245	667	72	470
BAL62976.1	3.88e-107	245	667	72	470
AXE90514.1	9.17e-102	929	1352	38	454
AMW14533.1	2.06e-101	924	1352	26	450

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7V6M_A	4.33e-28	243	775	2	558	ChainA, Fibronectin type III domain-containing protein [Tyzzerella nexilis]
6KQT_A	2.73e-19	249	663	244	642	CrystalStructure of GH136 lacto-N-biosidase from Eubacterium ramulus - native protein [Eubacterium ramulus ATCC 29099]
7V6I_A	3.17e-19	244	775	8	590	ChainA, Lacto-N-biosidase [Bifidobacterium saguini DSM 23967]
5GQC_A	6.95e-19	248	775	16	578	Crystalstructure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_B Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_C Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_D Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_E Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_F Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_G Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_H Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQF_A Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, lacto-N-biose complex [Bifidobacterium longum subsp. longum],5GQF_B Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, lacto-N-biose complex [Bifidobacterium longum subsp. longum],5GQG_A Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, galacto-N-biose complex [Bifidobacterium longum subsp. longum],5GQG_B Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, galacto-N-biose complex [Bifidobacterium longum subsp. longum]
6KQS_A	1.43e-18	249	663	244	642	CrystalStructure of GH136 lacto-N-biosidase from Eubacterium ramulus - selenomethionine derivative [Eubacterium ramulus ATCC 29099]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.002966	0.995923	0.000258	0.000438	0.000207	0.000168

TMHMM  Annotations     

start	end
13	32