CAZyme Information: MGYG000000150_06131

Basic Information

• Species: Hungatella sp005845265
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella; Hungatella sp005845265
• CAZyme ID: MGYG000000150_06131
• CAZy Family: GH136
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1931	MGYG000000150_47|CGC1	211662.55	4.2557

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000150	7470188	Isolate	United Kingdom	Europe

• Gene Location: Start: 12324; End: 18119 Strand: +

Full Sequence      

MYSLSRWKTRMTACILSGVVAFGTLFPVPAEAAGKTAVYDGREIVDLAGNSEMKAYGERL
VTGGKASVSRDYGGEAGAGISYYLDSESGNDENEGTSEDKPWKSLKMVNNRTFQPGDRIL
LKAGSVWKEETLSPKGSGEEGNPIVIGAYGDGDKPKLEGNAAVPEVVSLYNQQYWEISDL
EITNTAAGFTGAMNDQNGNKLKDVRGIRIAGQDGGDLNNFYLHDLHVHDVTGVCAWISGD
SNGKPGILGKQGWDKSKRTGGIVFEVMEPATDQPTVFHDITVERNVVNNNSFGGIIIKQW
KGADTGGEHWASREEGKGNAANNYFCENWKPHTDVTIRDNYLSQENSDYACNTIYLTSVQ
GAVVEGNISKEAGTCGIEMYYADDVTVQRNEVYKTRVKAGGADSNAIDPDKASTNILIQY
NYIHDTGDGILLCGFIFGTSVVRYNVIKDAQKRYINPHGDKGVNYVYNNILYNTIEKSNL
PFIESSGGNSVYLNKSGNMHYFNNNIFYNTAKTTTSVGIGEGTSTSYDSNCYYGKGVQAP
EQETHAVCGDPMFEGELTGSGEEGPEELLKLRLKTESPLLNAGIEVEDDPLLSVSANPGT
DFAGDPVFNGEPDMGIFEYQGEAGSGILNGYVEDPYGNIMKGASVKLKDTDYAAVTNEQG
FFAIAGVKPGSYTAVISKEIYLDGETPDITVEEKAVTRVQLKLGESLSDVGSVKGCVSNS
SGPLQGVTVTVSLEDQVYTVKTRNDGCYEIPDVKIGTGYEVTASKEGYKTATEKDVRIMP
AAVSEVNLILSREVGKTTYLIADLFDQYDTGAFTNNSRGNELWKVSDISAADSAKASLQI
KAEANGNKYLEMAKNGSYNLYAYTKKEYDLNGIITVEARVKRTKETASPNQFGMYSFNKA
DFKTGDPTSSSNAIGTFALSKGNIITHNKKGSSSTVNVQPYEKGRWDIIRNVINLDTNTF
DFYVNDMNVPKLADQPLRTQGKNIDRFEFFSSSTNGGDLLIDYFKVCTGPAMDYNDAGLS
GISVDGKEAEWKGENIYEMQIPSGSSEVKVQPSANSIFVKKVMVGGKDATKEAVSVPVPE
AGEPLLITVLAEDGETEERYQLNLVKEDVSGLAYLTNLTIEGITLTPEFDFNTMEYEGNV
PSDVHSVTLQYETVQASNEVTVKVNNQEVTDRVIPLKPGVNVIEIGIASADGTSFADYTV
TVTRDCVIDEIQIDTLPVKTVYERGEEPDFEGLTVGAYCEGDRVRSLEAAEFTVSMPDTS
KAGTVSVTVTYETEDGKTLEASFDITVYDRDTMQPQSIKVVKQPEQTVYGTGEAFNPDGM
EVRLLMKATASNAAPAEVRILDDGEYDVMDDFTEPGDTMVTIRYSWTDSNGEERYLEDQV
AVTVYDEELEYYQTGIKVTKQPKKTVYETGSIFDPDGMEVKRIMKASGSNADYYQETITD
YDYETAELTGTGSRKIAIRHEGTDENGDEQTFKAVVTVTVTNREDVLNNAVLKQSVAEAG
EKLNKEYVAYMTDEEKDSAANAAKNVFLDVMGAEHTVLTKDMADRMAELEALLKNAYPDI
TVRIEGDSSLTEGAKVTGTLLNAPFGQGNVRMVPQITKTKLPEDIPQTKAATAMEIKLLA
NGEELQPDIPLYLTLKIPEGLDRKDLIVYCELDDGSIKAVNPEISGEFLHFFVRSAGTFV
IANPKENDLTEIEITAKPKKTEYRINESFDAAGLVVTAVYEDGTRTVVTGYEMAGFDSTV
AGTKTITVFYQGKTAEFTVMVKADEDGPDDDDKDDDHDKDDDYNSDHGSHGSSGGSSAVR
TVLPDTVKGNWRQDENGWWFETTDGGYVVSDWARINEKWYYFNEQGYMAAGWVLDQNHWY
YLGEDGVMADYTWILDRGTWYFLQSGGVMAADQWVLWNGNWYYLSSDGSMARDTVITVGY
RIDEDGVWRPN

Enzyme Prediction     

No EC number prediction in MGYG000000150_06131.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH136	81	618	1.4e-118	0.9918533604887984

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
NF033838	PspC_subgroup_1	7.50e-26	1804	1911	481	585	pneumococcal surface protein PspC, choline-binding form. The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
NF033840	PspC_relate_1	2.57e-25	1798	1928	499	646	PspC-related protein choline-binding protein 1. Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.
NF033930	pneumo_PspA	1.17e-23	1804	1911	438	542	pneumococcal surface protein A. The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.
COG5263	COG5263	1.51e-23	1806	1928	191	312	Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism].
NF033930	pneumo_PspA	4.17e-23	1811	1911	485	582	pneumococcal surface protein A. The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CQR57267.1	5.10e-178	79	1202	39	1145
ASA23882.1	1.68e-175	78	1265	38	1212
QDH21977.1	2.64e-174	82	1204	53	1155
QFY07415.1	2.32e-159	76	1382	29	1262
BBC61707.1	2.50e-156	76	618	75	598

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7V6M_A	4.00e-39	75	618	4	576	ChainA, Fibronectin type III domain-containing protein [Tyzzerella nexilis]
5GQC_A	5.22e-28	78	618	16	596	Crystalstructure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_B Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_C Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_D Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_E Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_F Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_G Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQC_H Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, ligand-free form [Bifidobacterium longum subsp. longum],5GQF_A Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, lacto-N-biose complex [Bifidobacterium longum subsp. longum],5GQF_B Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, lacto-N-biose complex [Bifidobacterium longum subsp. longum],5GQG_A Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, galacto-N-biose complex [Bifidobacterium longum subsp. longum],5GQG_B Crystal structure of lacto-N-biosidase LnbX from Bifidobacterium longum subsp. longum, galacto-N-biose complex [Bifidobacterium longum subsp. longum]
6KQS_A	1.65e-26	79	500	244	663	CrystalStructure of GH136 lacto-N-biosidase from Eubacterium ramulus - selenomethionine derivative [Eubacterium ramulus ATCC 29099]
6KQT_A	2.19e-26	79	500	244	663	CrystalStructure of GH136 lacto-N-biosidase from Eubacterium ramulus - native protein [Eubacterium ramulus ATCC 29099]
7V6I_A	1.93e-23	75	618	9	608	ChainA, Lacto-N-biosidase [Bifidobacterium saguini DSM 23967]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
A0A401ETL2	3.61e-08	1698	1768	1381	1458	Exo-beta-1,6-galactobiohydrolase OS=Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) OX=565042 GN=bl1,6Gal PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000320	0.998933	0.000212	0.000193	0.000185	0.000158

TMHMM  Annotations     

start	end
13	30