CAZyme Information: MGYG000000152_02492

Basic Information

• Species: Lacrimispora sp902363835
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Lacrimispora; Lacrimispora sp902363835
• CAZyme ID: MGYG000000152_02492
• CAZy Family: GH136
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1571	MGYG000000152_10|CGC1	172703.16	4.4637

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000152	6260407	Isolate	United Kingdom	Europe

• Gene Location: Start: 73077; End: 77792 Strand: +

Full Sequence      

MLKSSRLFKRKAAGMMAAVMMIGILPVNMIGFADVLEMPSDSYENMDENIATRSNASYAT
ESIAQKAQELQEEGTVYYVDAKNGNDSGDGKTEETAWKTFDRVNSKTFLPGDKILLKADC
IWNQALNPKGSGREGAPITIDQYGEGNRPVINGNGTSGPSITGAVTIYNEEYWEIYNLEV
TNLEDTDKMGESMDSGTSERAGILIYSSNQKKIYKHITVKNCYVHDVNSNFKGGKTSGGI
IVMGHYLDKDGNRVTIDDAGNLTAKAMGRAAFEDVLIEGNYVKNVAIEGIRNKCNTDISS
SGWGKNEFLKNYSNVTIRNNYLENVVGDGIVLTETKGGLIEGNMVNSSCGFDRGAVNYAQ
CWTMFADNVTVQYNEVYGNRYGYDDGEAFDSDMMNVDNVFQYNLSHDCGGGAMLFMASQK
NTIFRYNISINDGTGTYPGESRLQQQTFHYDNTTSAGPGVGKIYNNTIVLFGEDKKTSLF
GGLSKRTCFVDFKNNIVLAKDGATIDFAVLAQGSMIHDDSVIENNCFYPDSIANTSAGSV
LNKESLEAKGNIFKDPMLVDYKAGKDYSQYKYPLEELEDLMDSDFTKERIQKLAEPYQLT
DGSPCIRAGQRIEGMPTEDIMGNTIAGRVDMGALEYSSEDEMAEEVEEVHIVTTPGVVPK
LPATLKIVLDGKSYDYPVKWDDLTKEDCMEAGIIELAGVLPGLSNQVAAVIIIADAPESF
EPVEVSTFAGIYPVLPDQVTAEFAGGLTLELGVTWETLTLEQYSHEGEIIVEGTVSGLKE
KCRAKVTVMGELGDGASVKEKVTSKDAYTQQSDGNKAYGSSDPNVIKVKTANNSPSYTRN
GLIGFDLSDEEQMLKSASSITIKLQMTRPVSEADYKTINNHFYLKVYEVSDNWAEGTVTW
NSSPAVSHDKLVINDKKIVYANIRDAHENIVELDVTDWVKNAYAKKEQTKFSFLMITDYF
GEYANGDNGGIDFASKEAAGKMAPTMVLSNVYETEVEAVSVSTPAGKMPGLPETVSVSYS
NGEQKNVAVEWNSVESAKYQSEGNFVVYGKANGVRLPIKCTVYVMEAMHKVVSIKDIPPI
IQLVGTPWEELGLPKTAAALLDNGKEAEVPIEYWFPDNAYDPEKVFSYTCIGYLDLTGHE
TIENPNQKFATVTVSIIEPEDKNALLVLYTEAADLINQGALDRLTDGAKSRFMKAFSQAA
AVLINTKATESEVHKSYVNLMEAIWNLDSEENVKPDTSALRDLVLIGESKNKKDYTEESY
EALKDALSEAKSVLKDKTLTKGDQYRVDQAYDYLKEAIDGLEFSGNSGSENRIVTGIKIV
ALPNQTEYKAGERISHFGLKVAAVYSDDSLKIINDYEISDVSTSVPGVKDVIITYRTAVN
NAIKVFSDVFQITVIKETSQGSGSGSSGGGTSSQRTGTGISGQWQKVNGTEWRFLKADKT
YAANEWAKISGKWYRFNENGMMQTGWIVDQGIWYRLSPNGDMESGWIKEESDGNWYFLDE
SGAMRTGWVLINGIWYYFNPVTQGETGWQKTEGGKWGHQTGVSGSRPMGALCTNTTTADG
YRVDENGAWIR

Enzyme Prediction     

No EC number prediction in MGYG000000152_02492.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH136	74	635	2.3e-122	0.9959266802443992

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
NF033930	pneumo_PspA	5.73e-32	1424	1570	485	660	pneumococcal surface protein A. The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.
NF033840	PspC_relate_1	5.04e-30	1424	1571	512	648	PspC-related protein choline-binding protein 1. Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.
NF033838	PspC_subgroup_1	1.56e-29	1424	1570	508	683	pneumococcal surface protein PspC, choline-binding form. The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
COG5263	COG5263	1.97e-26	1415	1570	187	313	Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism].
NF033679	DNRLRE_dom	5.35e-20	805	988	1	163	DNRLRE domain. The DNRLRE domain, with a length of about 160 amino acids, appears typically in large, repetitive surface proteins of bacteria and archaea, sometimes repeated several times. It occurs, notably, three times in the C-terminal region of the enzyme disaggregatase from the archaeal species Methanosarcina mazei, each time with the motif DNRLRE, for which the domain is named. Archaeal proteins within this family are described particularly well by the currently more narrowly defined Pfam model, PF06848. Note that the catalytic region of disaggregatase, in the N-terminal portion of the protein, is modeled by a different HMM, PF08480.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SET83278.1	0.0	1	1571	1	1571
ADL05164.1	0.0	1	1571	1	1579
QRV20653.1	0.0	1	1571	1	1579
QTI51982.1	1.24e-153	70	1122	47	1128
BBD28515.1	2.38e-153	70	1122	47	1128

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7V6M_A	6.28e-32	73	638	7	579	ChainA, Fibronectin type III domain-containing protein [Tyzzerella nexilis]
6KQT_A	1.98e-21	27	415	188	599	CrystalStructure of GH136 lacto-N-biosidase from Eubacterium ramulus - native protein [Eubacterium ramulus ATCC 29099]
6KQS_A	1.81e-20	74	415	244	599	CrystalStructure of GH136 lacto-N-biosidase from Eubacterium ramulus - selenomethionine derivative [Eubacterium ramulus ATCC 29099]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000477	0.998758	0.000198	0.000209	0.000170	0.000148

TMHMM  Annotations     

start	end
13	35