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CAZyme Information: MGYG000000157_02474

You are here: Home > Sequence: MGYG000000157_02474

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Paraclostridium sordellii
Lineage Bacteria; Firmicutes_A; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Paraclostridium; Paraclostridium sordellii
CAZyme ID MGYG000000157_02474
CAZy Family GH18
CAZyme Description Peroxiredoxin
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
588 MGYG000000157_86|CGC1 66288.49 5.2916
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000157 3456733 Isolate China Asia
Gene Location Start: 6003;  End: 7769  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000157_02474.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH18 267 559 6.7e-60 0.8581081081081081

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK13189 PRK13189 3.87e-123 3 213 7 222
peroxiredoxin; Provisional
cd03016 PRX_1cys 2.63e-115 7 211 1 203
Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by reducing and detoxifying hydrogen peroxide, peroxynitrite, and organic hydroperoxides. As with all other PRXs, a cysteine sulfenic acid intermediate is formed upon reaction of 1-cys PRX with its substrates. Having no resolving cysteine, the oxidized enzyme is resolved by an external small-molecule or protein reductant such as thioredoxin or glutaredoxin. Similar to typical 2-cys PRX, 1-cys PRX forms a functional dimeric unit with a B-type interface, as well as a decameric structure which is stabilized in the reduced form of the enzyme. Other oligomeric forms, tetramers and hexamers, have also been reported. Mammalian 1-cys PRX is localized cellularly in the cytosol and is expressed at high levels in brain, eye, testes and lung. The seed-specific plant 1-cys PRXs protect tissues from reactive oxygen species during desiccation and are also called rehydrins.
cd06548 GH18_chitinase 7.97e-90 266 555 20 322
The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an eight-stranded alpha/beta barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel.
COG0450 AhpC 7.51e-85 1 192 1 194
Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin) [Defense mechanisms].
PRK13190 PRK13190 1.72e-82 7 210 4 201
putative peroxiredoxin; Provisional

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AUN13970.1 0.0 1 588 1 588
CEK37813.1 0.0 1 588 1 588
QYE99248.1 0.0 1 588 1 588
CEJ73325.1 0.0 1 588 1 588
QEZ68091.1 0.0 1 587 4 590

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6TSB_AAA 1.00e-187 233 583 15 365
ChainAAA, Peroxiredoxin [Clostridioides difficile 630]
6T9M_AAA 1.99e-187 233 583 34 384
ChainAAA, Peroxiredoxin [Clostridioides difficile 630]
5OVQ_D 3.19e-79 4 208 6 218
CrystalStructure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_F Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_G Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_H Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_I Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_J Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_L Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5]
5OVQ_A 3.29e-79 4 208 6 218
CrystalStructure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_B Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_C Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_E Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5],5OVQ_K Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF [Aquifex aeolicus VF5]
6Q5V_A 7.35e-60 4 209 6 209
1-CysSiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A],6Q5V_B 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A],6Q5V_C 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A],6Q5V_D 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A],6Q5V_E 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A],6Q5V_F 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A],6Q5V_G 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A],6Q5V_H 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A],6Q5V_I 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A],6Q5V_J 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus [Sulfolobus islandicus REY15A]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q8R844 1.92e-100 3 209 13 218
Peroxiredoxin 2 OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) OX=273068 GN=TTE2186 PE=3 SV=1
O67024 5.70e-80 4 208 6 218
Peroxiredoxin OS=Aquifex aeolicus (strain VF5) OX=224324 GN=aq_858 PE=1 SV=1
Q8PYP6 6.13e-70 4 212 1 216
Peroxiredoxin OS=Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) OX=192952 GN=MM_0814 PE=3 SV=1
Q979N7 4.89e-66 7 210 5 202
Peroxiredoxin OS=Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1) OX=273116 GN=TV1123 PE=3 SV=1
Q6L140 1.78e-65 7 207 5 198
Peroxiredoxin 2 OS=Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828) OX=263820 GN=PTO0727 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000070 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000157_02474.