logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000000169_01969

You are here: Home > Sequence: MGYG000000169_01969

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Eubacterium_G sp000432355
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Eubacterium_G; Eubacterium_G sp000432355
CAZyme ID MGYG000000169_01969
CAZy Family GH65
CAZyme Description Nigerose phosphorylase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
727 MGYG000000169_8|CGC3 82315.57 4.7386
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000169 2836880 Isolate China Asia
Gene Location Start: 89561;  End: 91744  Strand: +

Full Sequence      Download help

MIDWKLKEEG  FDKEKISYLG  NKFLTGNGYM  GVRGTLAEYG  KENLAAINLA  GIYDKVGDGW60
REPLNAPNGF  YTYLVVDGEV  LKLPDVNPEV  HYTELDYRNG  IFTRHSEWDT  ARGKITFDSE120
RFVSMSDVHL  GGMKFKVTAD  FHADVEVVYG  IDGDVWDING  PHYDKLEYIE  NDVIGIIGTT180
HEKGYKVAVC  GGDKTSFPCE  KKINVHDKKV  LKSINFVTDI  NKEYVIERFF  GVYTSKDCEN240
CVEEASKEVT  VALRNGYEDA  IEKHKDKWNS  LWENSQVIVE  GDDKAMEALN  YSLYHLHCIA300
PRHTDSLSIA  ARGLSGQTYK  GAVFWDTEMF  ILDFFLMTEP  KVAKSLMKYR  IDSLSGAKEK360
AKSYGLDGAF  YAWESQEGGF  DACSDYNVVD  VFTKRPMRTF  FKDKQVHISS  AVVYGIGKYL420
KTTGDTSILS  EGGAHTIIEC  ALFYYSLLLK  RAVRDYYEIH  DVIGPDEYHE  RVNNNGYTNR480
MAKYTFEEAV  NVINLKDELS  EEEQEILSQY  DLDDLKNKFT  DAAENLFIPQ  PNENGVIPQF540
DGYFDLEDAS  IDEVRSRLLD  PKEYWGGAYG  VASHTQVIKQ  ADVVTWLNMF  SKEFDLDTML600
KNLEYYETRT  EHGSSLSACM  YALLACKCNR  PDKAYDFFMK  SASADIKQGG  KEWAGLVYIG660
GTHPAAAGGA  YMVALQGFGG  LSFDGDEIIV  KPNLPESWNR  LCFRVNYNNR  LYEIDINEAG720
VTKKELS727

Enzyme Prediction      help

EC 2.4.1.279

CAZyme Signature Domains help

Created with Snap3672109145181218254290327363399436472508545581617654690291685GH65
Family Start End Evalue family coverage
GH65 291 685 9.8e-117 0.9919354838709677

CDD Domains      download full data without filtering help

Created with Snap36721091451812182542903273633994364725085455816176546903722ATH14727PRK13807291688Glyco_hydro_65m8235Glyco_hydro_65N692722Glyco_hydro_65C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG1554 ATH1 0.0 3 722 10 739
Trehalose and maltose hydrolase (possible phosphorylase) [Carbohydrate transport and metabolism].
PRK13807 PRK13807 8.02e-112 4 727 10 733
maltose phosphorylase; Provisional
pfam03632 Glyco_hydro_65m 1.75e-108 291 688 2 387
Glycosyl hydrolase family 65 central catalytic domain. This family of glycosyl hydrolases contains vacuolar acid trehalase and maltose phosphorylase.Maltose phosphorylase (MP) is a dimeric enzyme that catalyzes the conversion of maltose and inorganic phosphate into beta-D-glucose-1-phosphate and glucose. The central domain is the catalytic domain, which binds a phosphate ion that is proximal the the highly conserved Glu. The arrangement of the phosphate and the glutamate is thought to cause nucleophilic attack on the anomeric carbon atom. The catalytic domain also forms the majority of the dimerization interface.
pfam03636 Glyco_hydro_65N 3.32e-52 8 235 2 240
Glycosyl hydrolase family 65, N-terminal domain. This family of glycosyl hydrolases contains vacuolar acid trehalase and maltose phosphorylase.Maltose phosphorylase (MP) is a dimeric enzyme that catalyzes the conversion of maltose and inorganic phosphate into beta-D-glucose-1-phosphate and glucose. This domain is believed to be essential for catalytic activity although its precise function remains unknown.
pfam03633 Glyco_hydro_65C 4.38e-06 692 722 1 31
Glycosyl hydrolase family 65, C-terminal domain. This family of glycosyl hydrolases contains vacuolar acid trehalase and maltose phosphorylase.Maltose phosphorylase (MP) is a dimeric enzyme that catalyzes the conversion of maltose and inorganic phosphate into beta-D-glucose-1-phosphate and glucose. The C-terminal domain forms a two layered jelly roll motif. This domain is situated at the base of the catalytic domain, however its function remains unknown.

CAZyme Hits      help

Created with Snap36721091451812182542903273633994364725085455816176546901723BCK00434.1|GH652722ABX42243.1|GH65|2.4.1.2791723SET84809.1|GH651726QLY80561.1|GH652718ABX43667.1|GH65|2.4.1.279
Hit ID E-Value Query Start Query End Hit Start Hit End
BCK00434.1 7.03e-318 1 723 1 719
ABX42243.1 1.50e-301 2 722 1 747
SET84809.1 2.96e-301 1 723 1 721
QLY80561.1 3.80e-300 1 726 1 725
ABX43667.1 1.31e-271 2 718 1 740

PDB Hits      download full data without filtering help

Created with Snap367210914518121825429032736339943647250854558161765469047224KTP_A47224KTR_A237253WIQ_A47271H54_A47017FE3_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
4KTP_A 3.17e-132 4 722 14 730
ChainA, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10],4KTP_B Chain B, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10]
4KTR_A 4.46e-132 4 722 14 730
ChainA, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10],4KTR_B Chain B, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10],4KTR_C Chain C, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10],4KTR_D Chain D, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10],4KTR_E Chain E, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10],4KTR_F Chain F, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10],4KTR_G Chain G, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10],4KTR_H Chain H, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10]
3WIQ_A 8.69e-98 23 725 25 738
Crystalstructure of kojibiose phosphorylase complexed with kojibiose [Caldicellulosiruptor saccharolyticus DSM 8903],3WIR_A Crystal structure of kojibiose phosphorylase complexed with glucose [Caldicellulosiruptor saccharolyticus DSM 8903],3WIR_B Crystal structure of kojibiose phosphorylase complexed with glucose [Caldicellulosiruptor saccharolyticus DSM 8903],3WIR_C Crystal structure of kojibiose phosphorylase complexed with glucose [Caldicellulosiruptor saccharolyticus DSM 8903],3WIR_D Crystal structure of kojibiose phosphorylase complexed with glucose [Caldicellulosiruptor saccharolyticus DSM 8903]
1H54_A 1.37e-69 4 727 10 735
ChainA, Maltose Phosphorylase [Levilactobacillus brevis],1H54_B Chain B, Maltose Phosphorylase [Levilactobacillus brevis]
7FE3_A 5.19e-43 4 701 24 662
ChainA, Candidate alpha glycoside phosphorylase Glycoside hydrolase family 65 [Flavobacterium johnsoniae UW101],7FE3_B Chain B, Candidate alpha glycoside phosphorylase Glycoside hydrolase family 65 [Flavobacterium johnsoniae UW101],7FE3_C Chain C, Candidate alpha glycoside phosphorylase Glycoside hydrolase family 65 [Flavobacterium johnsoniae UW101],7FE4_A Chain A, Candidate alpha glycoside phosphorylase Glycoside hydrolase family 65 [Flavobacterium johnsoniae UW101],7FE4_B Chain B, Candidate alpha glycoside phosphorylase Glycoside hydrolase family 65 [Flavobacterium johnsoniae UW101],7FE4_C Chain C, Candidate alpha glycoside phosphorylase Glycoside hydrolase family 65 [Flavobacterium johnsoniae UW101]

Swiss-Prot Hits      download full data without filtering help

Created with Snap36721091451812182542903273633994364725085455816176546902722sp|A9KT32|NIGP_LACP74722sp|D6XZ22|GGP_BACIE4726sp|Q8L163|KOJP_THEBR4726sp|Q8RBL8|KOJP_CALS46703sp|P77154|KOJP_ECOLI
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A9KT32 3.01e-302 2 722 1 747
Nigerose phosphorylase OS=Lachnoclostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) OX=357809 GN=Cphy_1874 PE=1 SV=1
D6XZ22 7.07e-132 4 722 14 730
1,2-alpha-glucosylglycerol phosphorylase OS=Bacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10) OX=439292 GN=Bsel_2816 PE=1 SV=1
Q8L163 2.95e-106 4 726 19 757
Kojibiose phosphorylase OS=Thermoanaerobacter brockii OX=29323 GN=kojP PE=1 SV=1
Q8RBL8 3.26e-102 4 726 16 754
Kojibiose phosphorylase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) OX=273068 GN=kojP PE=3 SV=1
P77154 7.58e-97 6 703 7 692
Kojibiose phosphorylase OS=Escherichia coli (strain K12) OX=83333 GN=ycjT PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000077 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000169_01969.