logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000000191_02173

You are here: Home > Sequence: MGYG000000191_02173

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Weizmannia coagulans
Lineage Bacteria; Firmicutes; Bacilli; Bacillales_B; Bacillaceae_C; Weizmannia; Weizmannia coagulans
CAZyme ID MGYG000000191_02173
CAZy Family GH70
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
888 MGYG000000191_26|CGC1 99944.08 9.4547
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000191 2910060 Isolate China Asia
Gene Location Start: 8888;  End: 11554  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.1.-

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH70 338 731 1.2e-91 0.5367372353673724

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam02324 Glyco_hydro_70 1.24e-63 356 729 119 525
Glycosyl hydrolase family 70. Members of this family belong to glycosyl hydrolase family 70 Glucosyltransferases or sucrose 6-glycosyl transferases (GTF-S) catalyze the transfer of D-glucopyramnosyl units from sucrose onto acceptor molecules, EC:2.4.1.5. This family roughly corresponds to the N-terminal catalytic domain of the enzyme. Members of this family also contain the Putative cell wall binding domain pfam01473, which corresponds with the C-terminal glucan-binding domain.
PRK09441 PRK09441 9.11e-55 42 714 3 472
cytoplasmic alpha-amylase; Reviewed
cd11318 AmyAc_bac_fung_AmyA 1.41e-38 42 625 1 391
Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase). AmyA (EC 3.2.1.1) catalyzes the hydrolysis of alpha-(1,4) glycosidic linkages of glycogen, starch, related polysaccharides, and some oligosaccharides. This group includes bacterial and fungal proteins. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.
pfam02324 Glyco_hydro_70 4.05e-31 30 248 545 790
Glycosyl hydrolase family 70. Members of this family belong to glycosyl hydrolase family 70 Glucosyltransferases or sucrose 6-glycosyl transferases (GTF-S) catalyze the transfer of D-glucopyramnosyl units from sucrose onto acceptor molecules, EC:2.4.1.5. This family roughly corresponds to the N-terminal catalytic domain of the enzyme. Members of this family also contain the Putative cell wall binding domain pfam01473, which corresponds with the C-terminal glucan-binding domain.
cd11314 AmyAc_arch_bac_plant_AmyA 2.25e-16 44 146 1 90
Alpha amylase catalytic domain found in archaeal, bacterial, and plant Alpha-amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase). AmyA (EC 3.2.1.1) catalyzes the hydrolysis of alpha-(1,4) glycosidic linkages of glycogen, starch, related polysaccharides, and some oligosaccharides. This group includes AmyA from bacteria, archaea, water fleas, and plants. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AJH79253.1 0.0 2 887 1 887
AEH52441.1 0.0 2 887 1 887
QJE33912.1 0.0 16 887 3 875
AVD57793.1 0.0 16 888 3 877
AKM18207.1 0.0 4 750 3 749

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5JBE_A 9.21e-80 246 729 5 590
4,6-alpha-glucanotransferaseGTFB from Lactobacillus reuteri 121 complexed with an isomalto-maltopentasaccharide [Limosilactobacillus reuteri],5JBE_B 4,6-alpha-glucanotransferase GTFB from Lactobacillus reuteri 121 complexed with an isomalto-maltopentasaccharide [Limosilactobacillus reuteri]
5JBD_A 1.72e-79 246 729 33 618
4,6-alpha-glucanotransferaseGTFB from Lactobacillus reuteri 121 [Limosilactobacillus reuteri],5JBD_B 4,6-alpha-glucanotransferase GTFB from Lactobacillus reuteri 121 [Limosilactobacillus reuteri]
5JBF_A 4.55e-79 246 729 5 590
4,6-alpha-glucanotransferaseGTFB (D1015N mutant) from Lactobacillus reuteri 121 complexed with maltopentaose [Limosilactobacillus reuteri],5JBF_B 4,6-alpha-glucanotransferase GTFB (D1015N mutant) from Lactobacillus reuteri 121 complexed with maltopentaose [Limosilactobacillus reuteri]
7P38_A 8.95e-78 254 729 64 610
ChainA, Dextransucrase [Limosilactobacillus reuteri],7P38_B Chain B, Dextransucrase [Limosilactobacillus reuteri],7P39_A Chain A, Dextransucrase [Limosilactobacillus reuteri],7P39_B Chain B, Dextransucrase [Limosilactobacillus reuteri]
7DT1_A 3.00e-77 254 762 203 811
ChainA, Dextransucrase [Limosilactobacillus fermentum],7DT1_B Chain B, Dextransucrase [Limosilactobacillus fermentum]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P08987 2.34e-48 366 734 399 800
Glucosyltransferase-I OS=Streptococcus mutans serotype c (strain ATCC 700610 / UA159) OX=210007 GN=gtfB PE=3 SV=3
P13470 2.96e-47 367 734 426 826
Glucosyltransferase-SI OS=Streptococcus mutans serotype c (strain ATCC 700610 / UA159) OX=210007 GN=gtfC PE=1 SV=2
P29336 2.01e-46 254 729 218 781
Glucosyltransferase-S OS=Streptococcus downei OX=1317 GN=gtfS PE=3 SV=1
P49331 1.56e-45 257 729 245 826
Glucosyltransferase-S OS=Streptococcus mutans serotype c (strain ATCC 700610 / UA159) OX=210007 GN=gtfD PE=3 SV=3
P11001 1.27e-40 251 729 227 798
Glucosyltransferase-I OS=Streptococcus downei OX=1317 GN=gtfI PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.005171 0.984777 0.008865 0.000621 0.000282 0.000232

TMHMM  Annotations      download full data without filtering help

start end
7 26