CAZyme Information: MGYG000000193_02040

Basic Information

• Species: KLE1615 sp900066985
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; KLE1615; KLE1615 sp900066985
• CAZyme ID: MGYG000000193_02040
• CAZy Family: GH42
• CAZyme Description: Beta-galactosidase BgaA

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
240	MGYG000000193_19|CGC1	28499.22	5.7207

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000193	4116467	Isolate	China	Asia

• Gene Location: Start: 31756; End: 32478 Strand: -

Full Sequence      

MRHSIEMEKLTLGVCYYPEHWDRALWKDDLQRMKQYGIEVIRLAEFSWALMEPEEGKYDF
SFWDEFLALAAEENMKVVFCTPTATPPAWLSEKYPETLNADGDGNLMYHGMRCQHNLTSP
KYLEFCEKITRRMAEHFNKYDCIIGWQLDNEVNCETNEYYSKSDHEAFRAFLKERFGTLD
NLNEKMGTIFWSQTYTDWDQIHLARRSTVGTGIANPHMQLEQVRFISHSAVHYLHCRHQL

Enzyme Prediction     

No EC number prediction in MGYG000000193_02040.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH42	15	237	2.9e-80	0.5902964959568733

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam02449	Glyco_hydro_42	6.86e-89	15	229	1	212	Beta-galactosidase. This group of beta-galactosidase enzymes belong to the glycosyl hydrolase 42 family. The enzyme catalyzes the hydrolysis of terminal, non-reducing terminal beta-D-galactosidase residues.
COG1874	GanA	6.74e-58	7	201	13	208	Beta-galactosidase GanA [Carbohydrate transport and metabolism].
pfam01301	Glyco_hydro_35	1.52e-06	23	218	23	202	Glycosyl hydrolases family 35.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QNO17813.1	8.38e-100	4	240	22	256
QDA29199.1	8.25e-96	1	231	1	229
AIY07136.1	8.25e-96	1	231	1	229
AUS26818.1	8.25e-96	1	231	1	229
AHM66175.1	8.25e-96	1	231	1	229

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
1KWG_A	4.85e-56	12	227	2	215	Crystalstructure of Thermus thermophilus A4 beta-galactosidase [Thermus thermophilus],1KWK_A Crystal structure of Thermus thermophilus A4 beta-galactosidase in complex with galactose [Thermus thermophilus]
6LVW_A	3.58e-53	10	233	1	222	PolyextremophilicBeta-galactosidase from the Antarctic haloarchaeon Halorubrum lacusprofundi [Halorubrum lacusprofundi ATCC 49239]
6Y2K_A	3.21e-52	10	231	1	220	ChainA, beta-galactosidase [Marinomonas sp. ef1]
4UCF_A	2.38e-44	9	227	19	236	Crystalstructure of Bifidobacterium bifidum beta-galactosidase in complex with alpha-galactose [Bifidobacterium bifidum S17],4UCF_B Crystal structure of Bifidobacterium bifidum beta-galactosidase in complex with alpha-galactose [Bifidobacterium bifidum S17],4UCF_C Crystal structure of Bifidobacterium bifidum beta-galactosidase in complex with alpha-galactose [Bifidobacterium bifidum S17],4UZS_A Crystal structure of Bifidobacterium bifidum beta-galactosidase [Bifidobacterium bifidum S17],4UZS_B Crystal structure of Bifidobacterium bifidum beta-galactosidase [Bifidobacterium bifidum S17],4UZS_C Crystal structure of Bifidobacterium bifidum beta-galactosidase [Bifidobacterium bifidum S17]
4UOQ_A	1.88e-40	9	227	22	240	Nucleophilemutant (E324A) of beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 [Bifidobacterium animalis subsp. lactis Bl-04],4UOQ_B Nucleophile mutant (E324A) of beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 [Bifidobacterium animalis subsp. lactis Bl-04],4UOQ_C Nucleophile mutant (E324A) of beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 [Bifidobacterium animalis subsp. lactis Bl-04],4UOZ_A beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 nucleophile mutant E324A in complex with galactose [Bifidobacterium animalis subsp. lactis Bl-04],4UOZ_B beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 nucleophile mutant E324A in complex with galactose [Bifidobacterium animalis subsp. lactis Bl-04],4UOZ_C beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 nucleophile mutant E324A in complex with galactose [Bifidobacterium animalis subsp. lactis Bl-04]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q9X6C6	1.82e-57	12	233	2	221	Beta-galactosidase BgaT OS=Thermus brockianus OX=56956 GN=bgaT PE=1 SV=1
Q8GEA9	2.54e-57	12	227	2	215	Beta-galactosidase BgaA OS=Thermus sp. OX=275 GN=bgaA PE=1 SV=1
O69315	2.66e-55	12	227	2	215	Beta-galactosidase OS=Thermus thermophilus OX=274 PE=1 SV=1
O54315	7.28e-54	12	227	2	215	Beta-galactosidase BgaA OS=Thermus sp. OX=275 GN=bgaA PE=1 SV=1
D9SM34	4.55e-53	10	234	1	220	Beta-galactosidase BgaA OS=Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B) OX=573061 GN=bgaA PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000036	0.000003	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000193_02040.