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CAZyme Information: MGYG000000196_00131

You are here: Home > Sequence: MGYG000000196_00131

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Bacteroides thetaiotaomicron
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides thetaiotaomicron
CAZyme ID MGYG000000196_00131
CAZy Family GH97
CAZyme Description Glucan 1,4-alpha-glucosidase SusB
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
738 MGYG000000196_1|CGC2 84305.16 6.4689
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000196 6397474 Isolate China Asia
Gene Location Start: 161161;  End: 163377  Strand: +

Full Sequence      Download help

MKKRKILSLI  AFLCISFIAN  AQQKLTSPDN  NLVMTFQVDS  KGAPTYELTY  KNKVVIKPST60
LGLELKKEDN  TRTDFDWVDR  RDLTKLDSKT  NLYDGFEVKD  IQTATFDETW  QPVWGEEKEI120
RNHYNELAVT  LYQPMNDRSI  VIRFRLFNDG  LGFRYEFPQQ  KSLNYFVIKE  EHSQFGMNGD180
HIAFWIPGDY  DTQEYDYTIS  RLSEIRGLMK  EAITPNSSQT  PFSQTGVQTA  LMMKTDDGLY240
INLHEAALVD  YSCMHLNLDD  KNMVFESWLT  PDAKGDKGYM  QTPCNTPWRT  IIVSDDARNI300
LASRITLNLN  EPCKIADAAS  WVKPVKYIGV  WWDMITGKGS  WAYTDELTSV  KLGETDYSKT360
KPNGKHSANT  ANVKRYIDFA  AAHGFDAVLV  EGWNEGWEDW  FGNSKDYVFD  FVTPYPDFDV420
KEIHRYAASK  GIKMMMHHET  SASVRNYERH  MDKAYQFMAD  NGYNSVKSGY  VGNIIPRGEH480
HYGQWMNNHY  LYAVKKAADY  KIMVNAHEAT  RPTGICRTYP  NLIGNESARG  TEYESFGGNK540
VYHTTILPFT  RLVGGPMDYT  PGIFETHCNK  MNPANNSQVR  STIARQLALY  VTMYSPLQMA600
ADIPENYERF  MDAFQFIKDV  ALDWDETNYL  EAEPGEYITI  ARKAKGTDDW  YVGCTAGENG660
HTSKLVFDFL  TPGKQYIATV  YADAKDADWK  ENPQAYTIKK  GILTNKSKLN  LHAANGGGYA720
ISIKEVKDKS  EIKGIKRL738

Enzyme Prediction      help

EC 3.2.1.3 3.2.1.20

CAZyme Signature Domains help

Created with Snap367311014718422125829533236940544247951655359062766470112723GH97
Family Start End Evalue family coverage
GH97 12 723 5.3e-253 0.9920760697305864

CDD Domains      download full data without filtering help

Created with Snap3673110147184221258295332369405442479516553590627664701320621Glyco_hydro_9727312GH97_N624724GH97_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam10566 Glyco_hydro_97 4.39e-145 320 621 3 278
Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands.
pfam14508 GH97_N 1.05e-97 27 312 1 235
Glycosyl-hydrolase 97 N-terminal. This N-terminal domain of glycosyl-hydrolase-97 contributes part of the active site pocket. It is also important for contact with the catalytic and C-terminal domains of the whole.
pfam14509 GH97_C 1.77e-43 624 724 1 97
Glycosyl-hydrolase 97 C-terminal, oligomerization. Glycosyl-hydrolase-97 is made up of three tightly linked and highly conserved globular domains. The C-terminal domain is found to be necessary for oligomerization of the whole molecule in order to create the active-site pocket and the Ca++-binding site.

CAZyme Hits      help

Created with Snap36731101471842212582953323694054424795165535906276647011738QQA08181.1|GH971738BCA48258.1|GH971738QUT41578.1|GH971738ALJ44109.1|GH971738AAC44671.1|GH97|3.2.1.3
Hit ID E-Value Query Start Query End Hit Start Hit End
QQA08181.1 0.0 1 738 1 738
BCA48258.1 0.0 1 738 1 738
QUT41578.1 0.0 1 738 1 738
ALJ44109.1 0.0 1 738 1 738
AAC44671.1 0.0 1 738 1 738

PDB Hits      download full data without filtering help

Created with Snap3673110147184221258295332369405442479516553590627664701197382D73_A247382JKA_A227383WFA_A277245HQ4_A277245HQC_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2D73_A 0.0 19 738 19 738
CrystalStructure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2D73_B Crystal Structure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2ZQ0_A Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron],2ZQ0_B Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron]
2JKA_A 0.0 24 738 13 727
Nativestructure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKA_B Native structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKE_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKE_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKP_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482],2JKP_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482]
3WFA_A 0.0 22 738 2 718
Catalyticrole of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron],3WFA_B Catalytic role of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron]
5HQ4_A 6.63e-170 27 724 5 659
AGlycoside Hydrolase Family 97 enzyme from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8],5HQA_A A Glycoside Hydrolase Family 97 enzyme in complex with Acarbose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]
5HQC_A 6.63e-170 27 724 5 659
AGlycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]

Swiss-Prot Hits      download full data without filtering help

Created with Snap36731101471842212582953323694054424795165535906276647011738sp|G8JZS4|SUSB_BACTN1724sp|Q8A6L0|AGAL_BACTN42665sp|D7CFN7|AGAL_STRBB
Hit ID E-Value Query Start Query End Hit Start Hit End Description
G8JZS4 0.0 1 738 1 738
Glucan 1,4-alpha-glucosidase SusB OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=susB PE=1 SV=1
Q8A6L0 9.57e-63 1 724 1 662
Retaining alpha-galactosidase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_1871 PE=1 SV=1
D7CFN7 4.70e-26 42 665 57 572
Probable retaining alpha-galactosidase OS=Streptomyces bingchenggensis (strain BCW-1) OX=749414 GN=SBI_01652 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000493 0.998068 0.000818 0.000197 0.000195 0.000181

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000196_00131.