logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000000223_01974

You are here: Home > Sequence: MGYG000000223_01974

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species NSJ-61 sp003433845
Lineage Bacteria; Firmicutes; Bacilli; Erysipelotrichales; Erysipelotrichaceae; NSJ-61; NSJ-61 sp003433845
CAZyme ID MGYG000000223_01974
CAZy Family PL8
CAZyme Description Xanthan lyase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
932 MGYG000000223_8|CGC2 104364.58 5.0912
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000223 4367631 Isolate China Asia
Gene Location Start: 45485;  End: 48283  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000223_01974.

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL8 432 732 2.8e-76 0.9845559845559846

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd01083 GAG_Lyase 4.17e-157 45 801 4 693
Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.
pfam02278 Lyase_8 7.93e-73 433 731 4 252
Polysaccharide lyase family 8, super-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
pfam08124 Lyase_8_N 5.20e-55 51 389 2 323
Polysaccharide lyase family 8, N terminal alpha-helical domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
pfam02884 Lyase_8_C 8.23e-10 747 809 1 67
Polysaccharide lyase family 8, C-terminal beta-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QNM12884.1 0.0 1 932 1 932
QNG59953.1 6.23e-233 1 852 1 875
AZK44607.1 1.14e-213 1 852 5 847
AGN24444.1 8.22e-213 1 852 5 849
AYV34286.1 2.39e-212 1 852 5 847

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6F2P_A 6.79e-74 107 852 66 751
Structureof Paenibacillus xanthan lyase to 2.6 A resolution [Paenibacillus]
1J0M_A 1.14e-71 108 852 65 749
CrystalStructure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1],1J0N_A Crystal Structure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1]
2E22_A 7.59e-71 108 852 65 749
Crystalstructure of xanthan lyase in complex with mannose [Bacillus sp. GL1]
2E24_A 2.68e-70 108 852 65 749
ChainA, Xanthan lyase [Bacillus sp. GL1]
1X1H_A 9.45e-70 108 852 65 749
ChainA, xanthan lyase [Bacillus sp. GL1],1X1I_A Chain A, xanthan lyase [Bacillus sp. GL1],1X1J_A Chain A, xanthan lyase [Bacillus sp. GL1]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q9AQS0 5.47e-69 108 852 90 774
Xanthan lyase OS=Bacillus sp. (strain GL1) OX=84635 GN=xly PE=1 SV=1
Q53591 6.84e-62 157 758 358 927
Hyaluronate lyase OS=Streptococcus agalactiae serotype III (strain NEM316) OX=211110 GN=hylB PE=1 SV=2
Q54873 1.26e-60 103 765 347 953
Hyaluronate lyase OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=SP_0314 PE=1 SV=2
Q59801 4.76e-55 107 794 110 760
Hyaluronate lyase OS=Staphylococcus aureus (strain NCTC 8325 / PS 47) OX=93061 GN=hysA PE=3 SV=1
P0CZ01 5.40e-32 106 852 99 796
Hyaluronate lyase OS=Cutibacterium acnes (strain DSM 16379 / KPA171202) OX=267747 GN=PPA0380 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000460 0.998807 0.000242 0.000174 0.000151 0.000139

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000223_01974.