CAZyme Information: MGYG000000244_02116

Basic Information

• Species: Catenibacterium sp000437715
• Lineage: Bacteria; Firmicutes; Bacilli; Erysipelotrichales; Erysipelatoclostridiaceae; Catenibacterium; Catenibacterium sp000437715
• CAZyme ID: MGYG000000244_02116
• CAZy Family: GT51
• CAZyme Description: Penicillin-binding protein 1A/1B

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
885		96903.26	7.0245

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000244	2463343	Isolate	China	Asia

• Gene Location: Start: 9928; End: 12585 Strand: +

Full Sequence      

MKVQSTKDPKQIKKTIKICIIALCVLVASGSGYLGFKIYQQISNFDIDNLTTTSYSSQVS
QDGETYYKYGSSIGKYVSYDDIPEIMIDAVVAAEDSRFFVHNGFDIPRIIKAFMSNILAG
HTVAGGSTITQQLIKKTYYPDAEKTIERKVGEVILSIEATQQTTKQKVLELYLNKIYFGK
SNSSIGIYGASYYYFGKSPDQLTLPEAALLAGTINSPVSYDPFKNLTLATKRRNIILNLM
YEHGYISEKERDNAKSVKVENILKYDPVQSNGKYASYVDRVTQEVKELGYDPNKTKMTIY
TYMDHDMQEYLDDVSSGKNYKFTDREMQAAASVLESKTGRIIGLMSAKNYRANNSDATYL
DYAYTLKNRRQPGSSIKPILDYATAFEYLNWSTGHTVDDSEFTQGSWHPKNWDNNYHDDV
LLEDALANSWNLAAIHTLNSVLKKVGNNQVVSFLKGLGYNMDDEDFNLNYAIGGWKYGTT
PTMQAAAYAAISNGGTYIKPHTIQKIVINTTGETINVDDDIQKQASEGMKDSTAFLLRQV
MTSYVKSNGSYSAFDIGSQIGAKTGTSNFDATIPALAGKDKDHWLCAYSPDYAWACWNGF
PAEISTKKHKYLASGMNDAKSIATKIAKKLATHKMKNSYETPSTVEKARMVKGVYPYVSP
SSSTPEEKIMTAWFVKGHGPSGVDDGSSYADEYKVPELTSFNASLNSNNSISVTFGSYDP
EYEGKITCVVEISDGSSTKTETLSSTSGTLEYSTESGKTYTVTGYYKLKSGDTTSNKKSV
RLSTGSTAVGTATFSVTANGAAISNGATISATSVNVSTSGPSGHTMIVTCNGNSQSLNCG
SSATISGLSSGRSYTISFTEKNSSGETKTIGSIHFTVQTTDTQEQ

Enzyme Prediction     

No EC number prediction in MGYG000000244_02116.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT51	64	241	1.5e-56	0.9830508474576272

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
TIGR02074	PBP_1a_fam	5.44e-142	74	622	2	520	penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG0744	MrcB	2.26e-134	76	622	78	588	Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
COG5009	MrcA	9.53e-94	22	600	14	691	Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].
TIGR02071	PBP_1b	1.19e-70	76	568	149	635	penicillin-binding protein 1B. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam00912	Transgly	8.52e-69	62	241	1	177	Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BBH26040.1	0.0	6	881	3	879
QUN13328.1	2.75e-231	4	884	6	918
BCL58334.1	5.65e-210	1	877	1	884
QQV07598.1	1.02e-204	14	877	18	878
QPS12598.1	2.04e-204	14	877	18	878

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3DWK_A	4.39e-79	75	600	28	557	ChainA, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_B Chain B, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_C Chain C, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_D Chain D, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL]
2OLU_A	1.91e-74	75	600	37	566	StructuralInsight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Apoenzyme [Staphylococcus aureus],2OLV_A Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex [Staphylococcus aureus],2OLV_B Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex [Staphylococcus aureus]
3ZG8_B	2.64e-47	158	614	2	443	CrystalStructure of Penicillin Binding Protein 4 from Listeria monocytogenes in the Ampicillin bound form [Listeria monocytogenes],3ZG9_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Cefuroxime bound form [Listeria monocytogenes],3ZGA_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Carbenicillin bound form [Listeria monocytogenes]
3ZG7_B	5.15e-44	158	614	2	443	CrystalStructure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the apo form [Listeria monocytogenes]
3UDF_A	1.29e-41	62	611	27	699	ChainA, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDF_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P39793	2.83e-103	4	719	17	730	Penicillin-binding protein 1A/1B OS=Bacillus subtilis (strain 168) OX=224308 GN=ponA PE=1 SV=1
Q04707	4.09e-82	14	664	11	655	Penicillin-binding protein 1A OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=ponA PE=1 SV=2
Q8DR59	1.09e-81	14	664	11	655	Penicillin-binding protein 1A OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) OX=171101 GN=pbpA PE=1 SV=1
Q00573	1.16e-77	11	600	8	600	Penicillin-binding protein 1A (Fragment) OS=Streptococcus oralis OX=1303 GN=ponA PE=3 SV=1
P38050	2.31e-67	11	646	3	618	Penicillin-binding protein 1F OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpF PE=2 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.999876	0.000147	0.000003	0.000001	0.000000	0.000014

TMHMM  Annotations     

start	end
20	42