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CAZyme Information: MGYG000000245_03044

You are here: Home > Sequence: MGYG000000245_03044

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Roseburia sp003470905
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia; Roseburia sp003470905
CAZyme ID MGYG000000245_03044
CAZy Family GH25
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1366 MGYG000000245_23|CGC2 148358.61 9.3709
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000245 4145433 Isolate China Asia
Gene Location Start: 41225;  End: 45325  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000245_03044.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH25 1169 1353 1.3e-34 0.9943502824858758

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd06414 GH25_LytC-like 5.42e-40 1167 1363 2 191
The LytC lysozyme of Streptococcus pneumoniae is a bacterial cell wall hydrolase that cleaves the beta1-4-glycosydic bond located between the N-acetylmuramoyl-N-glucosaminyl residues of the cell wall polysaccharide chains. LytC is composed of a C-terminal glycosyl hydrolase family 25 (GH25) domain and an N-terminal choline-binding module (CBM) consisting of eleven homologous repeats that specifically recognizes the choline residues of pneumococcal lipoteichoic and teichoic acids. This domain arrangement is the reverse of the major pneumococcal autolysin, LytA, and the CPL-1-like lytic enzymes of the pneumococcal bacteriophages, in which the CBM (consisting of six repeats) is at the C-terminus. This model represents the C-terminal catalytic domain of the LytC-like enzymes.
cd00599 GH25_muramidase 1.67e-24 1167 1361 1 185
Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. This family of muramidases contains a glycosyl hydrolase family 25 (GH25) catalytic domain and is found in bacteria, fungi, slime molds, round worms, protozoans and bacteriophages. The bacteriophage members are referred to as endolysins which are involved in lysing the host cell at the end of the replication cycle to allow release of mature phage particles. Endolysins are typically modular enzymes consisting of a catalytically active domain that hydrolyzes the peptidoglycan cell wall and a cell wall-binding domain that anchors the protein to the cell wall. Endolysins generally have narrow substrate specificities with either intra-species or intra-genus bacteriolytic activity.
cd06525 GH25_Lyc-like 1.49e-22 1167 1359 1 181
Lyc muramidase is an autolytic lysozyme (autolysin) from Clostridium acetobutylicum encoded by the lyc gene. Lyc has a glycosyl hydrolase family 25 (GH25) catalytic domain. Endo-N-acetylmuramidases are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues.
COG3401 FN3 2.96e-16 542 898 7 342
Fibronectin type 3 domain [General function prediction only].
pfam01183 Glyco_hydro_25 5.00e-15 1169 1353 1 180
Glycosyl hydrolases family 25.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
CBL14028.1 0.0 1 1366 1 1396
VCV23482.1 0.0 1 1366 1 1396
QUO20801.1 4.49e-119 323 1366 125 1060
VCV20908.1 1.09e-91 224 992 540 1287
CBL07763.1 1.32e-86 344 1070 556 1265

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3MPC_A 1.52e-06 1001 1069 8 77
ChainA, Fn3-like protein [Acetivibrio thermocellus ATCC 27405],3MPC_B Chain B, Fn3-like protein [Acetivibrio thermocellus ATCC 27405]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q9W6V5 1.61e-17 181 739 208 735
Receptor-type tyrosine-protein phosphatase eta OS=Gallus gallus OX=9031 GN=PTPRJ PE=2 SV=2
P50899 6.38e-16 426 725 708 1000
Exoglucanase B OS=Cellulomonas fimi (strain ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC 7547) OX=590998 GN=cbhB PE=1 SV=1
P34020 2.06e-11 1167 1359 2 177
Autolytic lysozyme OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) OX=272562 GN=lyc PE=1 SV=1
Q63870 7.91e-10 337 728 607 981
Collagen alpha-1(VII) chain OS=Mus musculus OX=10090 GN=Col7a1 PE=1 SV=3
A2ASS6 1.48e-09 344 1018 15292 15993
Titin OS=Mus musculus OX=10090 GN=Ttn PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.001894 0.693468 0.303841 0.000266 0.000269 0.000233

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000245_03044.