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CAZyme Information: MGYG000000262_02122

You are here: Home > Sequence: MGYG000000262_02122

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Anaerobutyricum hallii
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Anaerobutyricum; Anaerobutyricum hallii
CAZyme ID MGYG000000262_02122
CAZy Family GH36
CAZyme Description Alpha-galactosidase AgaA
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
729 MGYG000000262_12|CGC1 84096.32 6.0389
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000262 3404550 Isolate China Asia
Gene Location Start: 111497;  End: 113686  Strand: -

Full Sequence      Download help

MPVIYDDSKK  IFHLQSGNAS  YVMQVVKDKY  LAHLYWGKRL  SAYHGSRAII  WKDRGFAPNP60
DDKDRTFSLD  TLPQEYPQTG  NGDFRNCAYG  IRQKNGSRIS  SLFYKGYEIQ  EGKPELEGLP120
ASFAKKEEAQ  TLKIFLEDAV  AGLEVCLLYT  VWHDRDVITR  SVQFKNHSDS  EIILTKMLSM180
SLDIRESEFD  VMTLYGAHNN  ERNIDRRPLT  SGTVQIESLR  GTSSPHQSPF  MALLRKETNE240
DYGEVFAANF  VYSGNFTASA  QVDPYRNTRF  QMGMNPWNGE  WVLKPEKTFQ  TPEVVMVYSD300
RGLGQMSRTF  YHFYQECLIR  SKFAREPRPI  LVNNWEATFF  DFDEAKLLKL  ADKAQEAGIE360
LFVLDDGWFG  HRDADNSSLG  DWFVDRRKLP  HGLSELAKEI  HKRGMKFGLW  FEPEMISTDS420
GLFRKHPDYV  LHTEGRPYTI  GRGQLVLDLS  RKDVCDYVIK  SVSDVLKSTK  IDYVKWDMNR480
HLTDAGSVVF  SADQQGEIMH  RYVLGLYRIM  EEITEEFPDI  LFESCSSGGG  RFDPGMLYYM540
PQTWCSDNTD  AVCRMKIQYA  TSLMYPAVTM  GAHVSVIPNQ  QTGRVTPLDT  RGYVAMSGNL600
GYEIDLNQLS  EEEFQEVKKQ  IQLYKSIRNI  VQQGEFYRIH  NPFEENIAAW  NFVSKDKKEV660
LAFWFEILSQ  PAAPVHILKL  KGIDENAFYE  NLEDGRIYGG  DELMYCGISI  PLKKQDFRSV720
FYHFRKVEQ729

Enzyme Prediction      help

EC 3.2.1.22

CAZyme Signature Domains help

Created with Snap367210914518221825529132836440043747351054658361965669211709GH36
Family Start End Evalue family coverage
GH36 11 709 2.5e-286 0.997093023255814

CDD Domains      download full data without filtering help

Created with Snap367210914518221825529132836440043747351054658361965669212727GalA288634Melibiase327625GH3630284Glyco_hydro_36N647724Glyco_hydro_36C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3345 GalA 0.0 12 727 4 687
Alpha-galactosidase [Carbohydrate transport and metabolism].
pfam02065 Melibiase 0.0 288 634 1 347
Melibiase. Glycoside hydrolase families GH27, GH31 and GH36 form the glycoside hydrolase clan GH-D. Glycoside hydrolase family 36 can be split into 11 families, GH36A to GH36K. This family includes enzymes from GH36A-B and GH36D-K and from GH27.
cd14791 GH36 3.65e-154 327 625 1 298
glycosyl hydrolase family 36 (GH36). GH36 enzymes occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-galactosidase, alpha-N-acetylgalactosaminidase, stachyose synthase, and raffinose synthase. All GH36 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH36 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.
pfam16875 Glyco_hydro_36N 2.31e-118 30 284 2 256
Glycosyl hydrolase family 36 N-terminal domain. This domain is found at the N-terminus of many family 36 glycoside hydrolases. It has a beta-supersandwich fold.
pfam16874 Glyco_hydro_36C 1.42e-27 647 724 1 78
Glycosyl hydrolase family 36 C-terminal domain. This domain is found at the C-terminus of many family 36 glycoside hydrolases. It has a beta-sandwich structure with a Greek key motif.

CAZyme Hits      help

Created with Snap36721091451822182552913283644004374735105465836196566921728QGH26066.1|GH361728QGH22027.1|GH361727QUN34581.1|GH361726AOK91236.1|GH361727CUU50323.1|GH36
Hit ID E-Value Query Start Query End Hit Start Hit End
QGH26066.1 0.0 1 728 1 729
QGH22027.1 0.0 1 728 1 729
QUN34581.1 0.0 1 727 1 728
AOK91236.1 0.0 1 726 1 727
CUU50323.1 0.0 1 727 1 728

PDB Hits      download full data without filtering help

Created with Snap367210914518221825529132836440043747351054658361965669217294FNQ_A17294FNR_A17294FNU_A17294FNT_A17294FNP_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
4FNQ_A 3.86e-300 1 729 1 729
Crystalstructure of GH36 alpha-galactosidase AgaB from Geobacillus stearothermophilus [Geobacillus stearothermophilus]
4FNR_A 4.45e-299 1 729 1 729
Crystalstructure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNR_B Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNR_C Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNR_D Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus]
4FNU_A 4.18e-297 1 729 1 729
Crystalstructure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus],4FNU_B Crystal structure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus],4FNU_C Crystal structure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus],4FNU_D Crystal structure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus]
4FNT_A 5.92e-297 1 729 1 729
Crystalstructure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus],4FNT_B Crystal structure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus],4FNT_C Crystal structure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus],4FNT_D Crystal structure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus]
4FNP_A 8.40e-297 1 729 1 729
Crystalstructure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNP_B Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNP_C Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNP_D Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNS_A Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin [Geobacillus stearothermophilus],4FNS_B Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin [Geobacillus stearothermophilus],4FNS_C Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin [Geobacillus stearothermophilus],4FNS_D Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin [Geobacillus stearothermophilus]

Swiss-Prot Hits      download full data without filtering help

Created with Snap36721091451822182552913283644004374735105465836196566921729sp|Q9ALJ4|AGAA_GEOSE3729sp|P43467|AGAL1_PEDPE5727sp|G1UB44|MELA_LACAC1729sp|G4T4R7|AGASK_RUMGN1726sp|P27756|AGAL_STRMU
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q9ALJ4 2.44e-298 1 729 1 729
Alpha-galactosidase AgaA OS=Geobacillus stearothermophilus OX=1422 GN=agaA PE=1 SV=1
P43467 6.51e-252 3 729 4 732
Alpha-galactosidase 1 OS=Pediococcus pentosaceus OX=1255 GN=agaR PE=3 SV=1
G1UB44 7.21e-251 5 727 8 731
Alpha-galactosidase Mel36A OS=Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM) OX=272621 GN=melA PE=1 SV=1
G4T4R7 2.79e-221 1 729 1 722
Bifunctional alpha-galactosidase/sucrose kinase AgaSK OS=Ruminococcus gnavus OX=33038 GN=agaSK PE=1 SV=1
P27756 1.85e-200 1 726 1 719
Alpha-galactosidase OS=Streptococcus mutans serotype c (strain ATCC 700610 / UA159) OX=210007 GN=aga PE=3 SV=3

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000033 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000262_02122.