CAZyme Information: MGYG000000275_01944

Basic Information

• Species: Collinsella sp002232035
• Lineage: Bacteria; Actinobacteriota; Coriobacteriia; Coriobacteriales; Coriobacteriaceae; Collinsella; Collinsella sp002232035
• CAZyme ID: MGYG000000275_01944
• CAZy Family: GT2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
823		94276.28	5.1047

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000275	2352570	Isolate	China	Asia

• Gene Location: Start: 19134; End: 21605 Strand: -

Full Sequence      

MKKYNEQCPTNERQTMRVETTGVCRGNWKIYQRLKIEGIHKGSSVTAQAATDDNRCLPLS
LLKFRDNSCDSNSYVLVAPDPDARTIKIEFNEIGQDGRTLSSDSLSLNCKNIKWESRLNY
KIKPDMCSKLRDYDDVSEFDMATIDFWQCIEDSSDYILRCTVRTPYRSDSKIKLRCLDRT
LNEVDLSIVNFGSNVTSVGFTSEKKQLETQLSIRMPKAFDRYYFVIDDQNHPSFSAFDCL
TPDKLGLLLEETNFLFTHAQFDPEYPEWFTEHKATIGALEKQRKIVFDCAPKFSIIVPLY
NTPISFFNDMAESVKNQSYANWELILVNASPDNQELKARVEQETAHDNRIKSINLTENKG
ISENTNAGVAIASGDFVSFFDHDDILEPDLLFSYAEAIENNNDVDLLYCDEDKLMPDGKL
AQPFFKPDFNIDLLRNNNYICHMLTIRKSLLDTLEPNTKEFDGAQDHNLTLRAVEKARKV
HHVAKVLYHWRLSETSTAANADSKPYATIAGIKAVQSHLDRLGLNAKVEQARRPFTYKVT
YAVPVSHPLVSIIIPTKDHADILNNCIKSIVEKSTYDNYELVIIENNSTEKATFDYYDKL
QAKYPDIVRLETWEHEFNFSKLMNFGVAHAKGNYLLLLNNDTEVITPNWIETMLGICSRE
DVGAVGAKLYYPDDTIQHAGLCVTGGVAGHLCQSMPKDNWGYFALNDAQQDFSAVTAACI
MTKRSEYEKVGGFTEELQVAFNDVDFCLKLREINDLIVYTPEVELYHYESISRGVENNTE
KQIRFHKEVAYMNYRWAKHYVEGDPYMNPNFTVGEPANRYYHL

Enzyme Prediction     

No EC number prediction in MGYG000000275_01944.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	294	405	4.6e-20	0.6529411764705882
GT2	551	675	1.7e-19	0.711764705882353

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd04184	GT2_RfbC_Mx_like	5.01e-83	291	491	1	201	Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis. The rfbC gene encodes a predicted protein of 1,276 amino acids, which is required for O-antigen biosynthesis in Myxococcus xanthus. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.
cd04186	GT_2_like_c	6.85e-36	552	769	1	166	Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
COG1216	GT2	1.98e-24	548	796	3	242	Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism].
cd00761	Glyco_tranf_GTA_type	5.29e-19	295	409	1	113	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.
cd06433	GT_2_WfgS_like	5.37e-19	294	497	1	200	WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ATP53720.1	0.0	1	823	1	823
AZH69456.1	0.0	1	823	1	823
QOY61387.1	0.0	16	823	1	809
ACV56016.1	0.0	30	823	1	794
ACV56006.1	8.12e-205	16	823	1	829

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5HEA_A	9.34e-10	288	406	2	118	CgTstructure in hexamer [Streptococcus parasanguinis FW213],5HEA_B CgT structure in hexamer [Streptococcus parasanguinis FW213],5HEA_C CgT structure in hexamer [Streptococcus parasanguinis FW213],5HEC_A CgT structure in dimer [Streptococcus parasanguinis FW213],5HEC_B CgT structure in dimer [Streptococcus parasanguinis FW213]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P55465	2.81e-126	268	813	344	890	Uncharacterized protein y4gI OS=Sinorhizobium fredii (strain NBRC 101917 / NGR234) OX=394 GN=NGR_a03550 PE=4 SV=1
Q50864	8.72e-91	264	813	292	833	O-antigen biosynthesis protein RfbC OS=Myxococcus xanthus OX=34 GN=rfbC PE=4 SV=1
P71057	4.02e-13	291	533	4	252	Putative glycosyltransferase EpsH OS=Bacillus subtilis (strain 168) OX=224308 GN=epsH PE=2 SV=1
Q58457	1.73e-12	291	492	8	213	Uncharacterized glycosyltransferase MJ1057 OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) OX=243232 GN=MJ1057 PE=3 SV=2
Q57022	1.45e-07	291	464	4	177	Uncharacterized glycosyltransferase HI_0868 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=HI_0868 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000064	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000275_01944.