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CAZyme Information: MGYG000000277_00395

You are here: Home > Sequence: MGYG000000277_00395

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Streptococcus mutans
Lineage Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus mutans
CAZyme ID MGYG000000277_00395
CAZy Family GT51
CAZyme Description Penicillin-binding protein 1A
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
707 77815.69 6.526
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000277 2020595 Isolate China Asia
Gene Location Start: 416388;  End: 418511  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.1.129

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT51 54 231 2.7e-63 0.9887005649717514

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
TIGR02074 PBP_1a_fam 0.0 64 627 1 529
penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG0744 MrcB 0.0 26 663 35 633
Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
COG5009 MrcA 1.34e-97 26 617 24 720
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].
pfam00912 Transgly 4.60e-75 53 231 1 177
Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
COG4953 PbpC 9.59e-65 34 599 27 534
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ARS63557.1 0.0 1 665 1 665
QFG42670.1 0.0 1 665 1 665
AMF85932.1 0.0 1 665 37 701
BAH88527.1 0.0 1 665 37 701
QFG44537.1 0.0 1 665 1 665

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2V2F_F 2.74e-169 259 652 2 389
Crystalstructure of PBP1a from drug-resistant strain 5204 from Streptococcus pneumoniae [Streptococcus pneumoniae]
2ZC5_B 5.48e-169 259 652 2 389
ChainB, Penicillin-binding protein 1A [unidentified],2ZC5_D Chain D, Penicillin-binding protein 1A [unidentified],2ZC6_B Chain B, Penicillin-binding protein 1A [unidentified],2ZC6_D Chain D, Penicillin-binding protein 1A [unidentified]
2C5W_B 1.30e-168 260 650 1 385
PENICILLIN-BINDINGPROTEIN 1A (PBP-1A) ACYL-ENZYME COMPLEX (CEFOTAXIME) FROM STREPTOCOCCUS PNEUMONIAE [Streptococcus pneumoniae R6]
2C6W_B 5.05e-168 261 650 1 384
Penicillin-BindingProtein 1a (Pbp-1a) From Streptococcus Pneumoniae [Streptococcus pneumoniae]
3DWK_A 5.21e-92 49 657 10 619
ChainA, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_B Chain B, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_C Chain C, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_D Chain D, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q04707 7.36e-282 12 652 18 652
Penicillin-binding protein 1A OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=ponA PE=1 SV=2
Q8DR59 1.70e-280 12 652 18 652
Penicillin-binding protein 1A OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) OX=171101 GN=pbpA PE=1 SV=1
Q00573 1.14e-277 12 636 18 637
Penicillin-binding protein 1A (Fragment) OS=Streptococcus oralis OX=1303 GN=ponA PE=3 SV=1
P39793 7.22e-120 11 640 41 656
Penicillin-binding protein 1A/1B OS=Bacillus subtilis (strain 168) OX=224308 GN=ponA PE=1 SV=1
P38050 2.91e-76 36 600 38 570
Penicillin-binding protein 1F OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpF PE=2 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.998445 0.001112 0.000046 0.000011 0.000005 0.000425

TMHMM  Annotations      download full data without filtering help

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