CAZyme Information: MGYG000000284_00437

Basic Information

• Species: Parabacteroides sp900540715
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae; Parabacteroides; Parabacteroides sp900540715
• CAZyme ID: MGYG000000284_00437
• CAZy Family: GH2
• CAZyme Description: Evolved beta-galactosidase subunit alpha

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1341		150857.98	5.6567

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000284	5935659	MAG	Sweden	Europe

• Gene Location: Start: 47227; End: 51252 Strand: -

Full Sequence      

MQKLALCLLLCSFTFQSFATVDPLKGYQYASEQAPKGDEWESPENIALNKEQPHAWFFSF
KDPESARKVLPENSAYWQSLNGDWKFNWVRTPEERPKDFFQTNFDVSGWDNIPVPSSWNI
VGLQKDGSQKYGTPIYVNQPVIFQHKVAVDDWRGGVMRTPPENWTTFKDRNEVGSYRREF
TIPTDWEGKEVFINFDGVDSFFYLWINGQYVGFSKNSRNTASFNITPYLVKGTNIVAAEV
YRSSDGSFLEAQDMFRLPGIYRSVSLTAVPQLHVRDLVATPDLDATYTNGSLNIRADIRN
LGKKAAKNYSIVYSLYANKLYSDDNTKVDNATASAPIALVAAGQEIGTETVLTVQNPNKW
SAEQPYRYTLVGELKDKKGRTVETISTTVGFRKVEIKDTPASEDEFGLAGRYYYVNGKTV
KLKGVNRHESNPGVGHAITRKMMEDEVMLMKRANINHVRNSHYPDDPYWYYLCNKFGLYL
EDEANIESHEYYYGVASLSHPKEWRDAHVARVMEMVHANINNPSIVIWSLGNEAGPGQNF
VEAYNALKKADLSRPVQYERNNKIVDMGSNQYPSISWVRGAVKGDYDIKYPFHISEYAHS
MGNACGNLIDYWDAMESTNFFCGGAIWDWVDQSLYNYTPDGKRYLAYGGDFGDTPNDGQF
VMNGIVFGDLEPKPQYYEVKKVYQHIGVTEVDASKGLFEIFNKYYFNDLSDYAVKWSLYE
NGKEVESGSLNPGTVAPRKRVQVAVPYTYSKLKAENEYFVKVQFLLNENKPWADKGYVMA
EEQLPVKAATDKPAINEVANAATGKLTIDKQADPRFSTIKGDNFEIKFDNEIGTIYSLNY
NNETIIADGNGPKLDAFRAFTNNDNWFYGSWFENGLHNLKHRATASKVLNRKDGAIVLFY
TVESQAPNAAKILGGTSSGKNSVEELTDKVFGEDDFKFTTDQVWTIYRDGSIELQASITS
NNPSLVLPRLGYMMRVPQRYENYTYYGRGPVENYADRKVGQFIEMYKSTVADQFVNFPKP
QDMGNHEDVRWCALTDKTGKGAVFVATDRLSTSALQYSALDLTLSGHPYQLPKAGDTYLH
LDLAVTGLGGNSCGQGGPLVQDRVFAGQNNIGFIIRPAAQDLSAVAQVSAAGDIPFSITR
SRTGLVKLSSIDKEAVICYTIGKDKKAKEYTEAIPMREGGTITAWFKNNPEIKSTKTFNK
MESIQTEVIYASSEEVDGGDAKNLVDGDPNTIWHSMYSVTVAKYPHWVDLDAGEEKALKG
FIYLPRQDGSNGNIKEYSIQVSPDGKNWGEPVCKGWFANNKDEKKVLFDKPVKGRYIRFT
ALSSQNGQDFATGAELTVLSE

Enzyme Prediction     

No EC number prediction in MGYG000000284_00437.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	71	1003	3.3e-214	0.9680851063829787
CBM32	1211	1336	3.5e-25	0.9193548387096774

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK09525	lacZ	0.0	40	998	17	914	beta-galactosidase.
PRK10340	ebgA	0.0	40	1120	4	1002	cryptic beta-D-galactosidase subunit alpha; Reviewed
COG3250	LacZ	3.30e-132	70	1001	5	804	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
smart01038	Bgal_small_N	6.87e-82	820	1115	1	272	Beta galactosidase small chain. This domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.
pfam02836	Glyco_hydro_2_C	1.26e-74	413	686	8	300	Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QCQ47063.1	0.0	1	1341	1	1341
QLK84481.1	0.0	1	1341	1	1341
AUI47491.1	0.0	1	1341	1	1341
QTO25654.1	0.0	1	1341	1	1341
QCQ38420.1	0.0	1	1341	1	1341

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6S6Z_A	5.34e-193	39	1116	3	980	Structureof beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_B Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_C Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_D Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_E Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_F Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_G Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_H Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8]
6SD0_A	5.49e-193	39	1116	4	981	Structureof beta-galactosidase from Thermotoga maritima. [Thermotoga maritima MSB8],6SD0_B Structure of beta-galactosidase from Thermotoga maritima. [Thermotoga maritima MSB8],6SD0_C Structure of beta-galactosidase from Thermotoga maritima. [Thermotoga maritima MSB8],6SD0_D Structure of beta-galactosidase from Thermotoga maritima. [Thermotoga maritima MSB8]
3DEC_A	2.66e-183	39	1096	6	976	ChainA, Beta-galactosidase [Bacteroides thetaiotaomicron VPI-5482]
3BGA_A	3.51e-177	39	1096	9	980	Crystalstructure of beta-galactosidase from Bacteroides thetaiotaomicron VPI-5482 [Bacteroides thetaiotaomicron VPI-5482],3BGA_B Crystal structure of beta-galactosidase from Bacteroides thetaiotaomicron VPI-5482 [Bacteroides thetaiotaomicron VPI-5482]
3MUY_1	5.98e-118	39	1091	15	996	Chain1, Beta-D-galactosidase [Escherichia coli K-12],3MUY_2 Chain 2, Beta-D-galactosidase [Escherichia coli K-12],3MUY_3 Chain 3, Beta-D-galactosidase [Escherichia coli K-12],3MUY_4 Chain 4, Beta-D-galactosidase [Escherichia coli K-12]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
O52847	3.52e-194	39	1095	19	1010	Beta-galactosidase OS=Priestia megaterium (strain DSM 319 / IMG 1521) OX=592022 GN=bgaM PE=3 SV=1
Q56307	3.01e-192	39	1116	4	981	Beta-galactosidase OS=Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) OX=243274 GN=lacZ PE=1 SV=2
P06864	4.79e-159	38	1119	2	1001	Evolved beta-galactosidase subunit alpha OS=Escherichia coli (strain K12) OX=83333 GN=ebgA PE=1 SV=4
Q9K9C6	1.28e-156	40	1114	9	1008	Beta-galactosidase OS=Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) OX=272558 GN=lacZ PE=3 SV=1
A1SWB8	6.36e-153	36	1091	9	1008	Beta-galactosidase OS=Psychromonas ingrahamii (strain 37) OX=357804 GN=lacZ PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000361	0.998846	0.000248	0.000182	0.000178	0.000163

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000284_00437.