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CAZyme Information: MGYG000000294_00357
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Phascolarctobacterium_A sp900544885 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_C; Negativicutes; Acidaminococcales; Acidaminococcaceae; Phascolarctobacterium_A; Phascolarctobacterium_A sp900544885 | |||||||||||
| CAZyme ID | MGYG000000294_00357 | |||||||||||
| CAZy Family | GT83 | |||||||||||
| CAZyme Description | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 26541; End: 28124 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT83 | 3 | 471 | 3e-106 | 0.8981481481481481 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG1807 | ArnT | 1.03e-50 | 1 | 357 | 6 | 361 | 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis]. |
| PRK13279 | arnT | 2.20e-33 | 1 | 363 | 2 | 374 | lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase. |
| pfam13231 | PMT_2 | 1.85e-22 | 59 | 217 | 1 | 157 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366. |
| pfam02366 | PMT | 1.32e-12 | 31 | 223 | 32 | 236 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
| COG1287 | Stt3 | 0.004 | 59 | 229 | 86 | 273 | Asparagine N-glycosylation enzyme, membrane subunit Stt3 [Posttranslational modification, protein turnover, chaperones]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QTV78033.1 | 7.55e-238 | 1 | 525 | 1 | 524 |
| ADB46704.1 | 5.45e-149 | 1 | 522 | 1 | 530 |
| AEQ23377.1 | 1.09e-145 | 1 | 522 | 1 | 529 |
| AVO74995.1 | 2.52e-112 | 11 | 524 | 33 | 505 |
| CCC74317.1 | 2.52e-112 | 11 | 524 | 33 | 505 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5EZM_A | 9.14e-33 | 6 | 341 | 33 | 375 | CrystalStructure of ArnT from Cupriavidus metallidurans in the apo state [Cupriavidus metallidurans CH34],5F15_A Crystal Structure of ArnT from Cupriavidus metallidurans bound to Undecaprenyl phosphate [Cupriavidus metallidurans CH34] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| A4SQX1 | 2.23e-29 | 31 | 330 | 30 | 330 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Aeromonas salmonicida (strain A449) OX=382245 GN=arnT PE=3 SV=1 |
| O67270 | 2.23e-28 | 1 | 433 | 1 | 412 | Uncharacterized protein aq_1220 OS=Aquifex aeolicus (strain VF5) OX=224324 GN=aq_1220 PE=3 SV=1 |
| Q2NWA9 | 2.66e-28 | 31 | 366 | 34 | 372 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 1 OS=Sodalis glossinidius (strain morsitans) OX=343509 GN=arnT1 PE=3 SV=1 |
| A0KGY4 | 6.03e-28 | 31 | 331 | 30 | 332 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049) OX=380703 GN=arnT PE=3 SV=1 |
| A6V1N8 | 6.12e-28 | 20 | 328 | 23 | 329 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Pseudomonas aeruginosa (strain PA7) OX=381754 GN=arnT PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.903784 | 0.094476 | 0.001023 | 0.000169 | 0.000153 | 0.000406 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 5 | 27 |
| 80 | 102 |
| 123 | 145 |
| 160 | 191 |
| 203 | 225 |
| 253 | 275 |
| 292 | 309 |
| 313 | 330 |
| 342 | 361 |
| 371 | 390 |
| 395 | 417 |