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CAZyme Information: MGYG000000295_02509
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Clostridium_E sporosphaeroides | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; Clostridium_E; Clostridium_E sporosphaeroides | |||||||||||
| CAZyme ID | MGYG000000295_02509 | |||||||||||
| CAZy Family | GT4 | |||||||||||
| CAZyme Description | UDP-N-acetyl-D-mannosamine dehydrogenase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 49; End: 2565 Strand: - | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG1004 | Ugd | 9.23e-176 | 383 | 795 | 2 | 414 | UDP-glucose 6-dehydrogenase [Cell wall/membrane/envelope biogenesis]. |
| TIGR03026 | NDP-sugDHase | 2.36e-137 | 383 | 790 | 2 | 409 | nucleotide sugar dehydrogenase. Enzymes in this family catalyze the NAD-dependent alcohol-to-acid oxidation of nucleotide-linked sugars. Examples include UDP-glucose 6-dehydrogenase (1.1.1.22), GDP-mannose 6-dehydrogenase (1.1.1.132), UDP-N-acetylglucosamine 6-dehydrogenase (1.1.1.136), UDP-N-acetyl-D-galactosaminuronic acid dehydrogenase, and UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase. These enzymes are most often involved in the biosynthesis of polysaccharides and are often found in operons devoted to that purpose. All of these enzymes contain three Pfam domains, pfam03721, pfam00984, and pfam03720 for the N-terminal, central, and C-terminal regions respectively. |
| cd03814 | GT4-like | 3.29e-125 | 2 | 369 | 1 | 365 | glycosyltransferase family 4 proteins. This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes. |
| cd03817 | GT4_UGDG-like | 5.01e-77 | 2 | 371 | 1 | 372 | UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol. |
| PLN02353 | PLN02353 | 5.88e-68 | 382 | 809 | 2 | 467 | probable UDP-glucose 6-dehydrogenase |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AVI59029.1 | 1.30e-159 | 382 | 809 | 1 | 431 |
| CAB1245716.1 | 2.12e-129 | 1 | 370 | 1 | 370 |
| BCG58591.1 | 3.30e-129 | 1 | 368 | 1 | 368 |
| AIQ12274.1 | 2.59e-128 | 1 | 368 | 1 | 368 |
| AKG34176.1 | 1.58e-126 | 1 | 368 | 1 | 368 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 4A7P_A | 1.75e-100 | 382 | 809 | 9 | 442 | Se-Metderivatized UgdG, UDP-glucose dehydrogenase from Sphingomonas elodea [Sphingomonas elodea],4A7P_B Se-Met derivatized UgdG, UDP-glucose dehydrogenase from Sphingomonas elodea [Sphingomonas elodea] |
| 3GG2_A | 1.20e-97 | 382 | 794 | 3 | 424 | ChainA, Sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family [Porphyromonas gingivalis],3GG2_B Chain B, Sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family [Porphyromonas gingivalis],3GG2_C Chain C, Sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family [Porphyromonas gingivalis],3GG2_D Chain D, Sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family [Porphyromonas gingivalis] |
| 2Y0E_A | 4.50e-94 | 382 | 809 | 9 | 459 | BceCand the final step of UGDs reaction [Burkholderia cepacia],2Y0E_B BceC and the final step of UGDs reaction [Burkholderia cepacia],2Y0E_C BceC and the final step of UGDs reaction [Burkholderia cepacia],2Y0E_D BceC and the final step of UGDs reaction [Burkholderia cepacia] |
| 2Y0C_A | 9.20e-93 | 382 | 809 | 9 | 459 | BceCmutation Y10S [Burkholderia cepacia],2Y0C_B BceC mutation Y10S [Burkholderia cepacia],2Y0C_C BceC mutation Y10S [Burkholderia cepacia],2Y0C_D BceC mutation Y10S [Burkholderia cepacia] |
| 2Y0D_A | 9.20e-93 | 382 | 809 | 9 | 459 | BceCmutation Y10K [Burkholderia cepacia],2Y0D_B BceC mutation Y10K [Burkholderia cepacia],2Y0D_C BceC mutation Y10K [Burkholderia cepacia],2Y0D_D BceC mutation Y10K [Burkholderia cepacia] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P96718 | 2.24e-125 | 382 | 812 | 1 | 433 | UDP-glucose 6-dehydrogenase YwqF OS=Bacillus subtilis (strain 168) OX=224308 GN=ywqF PE=1 SV=1 |
| O32271 | 4.87e-116 | 383 | 812 | 3 | 434 | UDP-glucose 6-dehydrogenase TuaD OS=Bacillus subtilis (strain 168) OX=224308 GN=tuaD PE=1 SV=1 |
| O54068 | 1.90e-105 | 382 | 809 | 1 | 435 | UDP-glucose 6-dehydrogenase OS=Rhizobium meliloti (strain 1021) OX=266834 GN=rkpK PE=1 SV=2 |
| Q92GB1 | 1.63e-94 | 382 | 808 | 1 | 429 | UDP-glucose 6-dehydrogenase OS=Rickettsia conorii (strain ATCC VR-613 / Malish 7) OX=272944 GN=udg PE=3 SV=1 |
| Q4UK39 | 2.65e-94 | 382 | 808 | 1 | 431 | UDP-glucose 6-dehydrogenase OS=Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) OX=315456 GN=udg PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000059 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |