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CAZyme Information: MGYG000000307_00299

You are here: Home > Sequence: MGYG000000307_00299

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Rothia mucilaginosa
Lineage Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Micrococcaceae; Rothia; Rothia mucilaginosa
CAZyme ID MGYG000000307_00299
CAZy Family GT2
CAZyme Description Galactofuranosyltransferase GlfT2
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
668 MGYG000000307_8|CGC1 74800.47 6.2416
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000307 2184222 MAG Sweden Europe
Gene Location Start: 7468;  End: 9474  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000307_00299.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT2 195 447 4.9e-42 0.9695652173913043

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG1216 GT2 6.46e-44 198 513 9 305
Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism].
pfam17994 Glft2_N 5.93e-39 9 179 1 137
Galactofuranosyltransferase 2 N-terminal. This is the N-terminal beta-barrel domain found in the polymerizing galactofuranosyltransferase GlfT2 (Rv3808c). This enzyme synthesizes the bulk of the galactan portion of the mycolyl-arabinogalactan complex, which is the largest component of the mycobacterial cell wall such as in Mycobacterium tuberculosis. The N-terminal domain contains two short helices preceding a 10-stranded beta-sandwich with jelly roll topology.
pfam13641 Glyco_tranf_2_3 4.15e-31 195 445 5 226
Glycosyltransferase like family 2. Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis.
cd04185 GT_2_like_b 2.37e-16 198 448 3 202
Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
cd04186 GT_2_like_c 2.74e-12 198 424 3 164
Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
BAS20599.1 0.0 1 668 1 668
ATF63732.1 0.0 1 668 1 668
BAI64518.1 0.0 1 668 1 668
QXW98233.1 0.0 1 668 1 668
ADP39506.1 0.0 4 668 5 669

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4FIX_A 2.60e-126 76 654 63 642
CrystalStructure of GlfT2 [Mycobacterium tuberculosis H37Rv],4FIX_B Crystal Structure of GlfT2 [Mycobacterium tuberculosis H37Rv],4FIY_A Crystal Structure of GlfT2 Complexed with UDP [Mycobacterium tuberculosis H37Rv],4FIY_B Crystal Structure of GlfT2 Complexed with UDP [Mycobacterium tuberculosis H37Rv]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
A0R628 7.33e-133 76 668 54 646
Galactofuranosyltransferase GlfT2 OS=Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) OX=246196 GN=glfT2 PE=3 SV=1
O53585 8.01e-126 76 654 43 622
Galactofuranosyltransferase GlfT2 OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=glfT2 PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000072 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000307_00299.