dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000000328_00660

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Basic Information help

Species

CAG-272 sp900556615

Lineage

Bacteria; Firmicutes_A; Clostridia; Oscillospirales; CAG-272; CAG-272; CAG-272 sp900556615

CAZyme ID

MGYG000000328_00660

CAZy Family

GH36

CAZyme Description

Alpha-galactosidase Mel36A

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
728		82308.86	4.3738

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000328	1880403	MAG	Sweden	Europe

Gene Location

Start: 880; End: 3066 Strand: -

Full Sequence Download help

Enzyme Prediction help

No EC number prediction in MGYG000000328_00660.

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GH36	105	710	3.5e-42	0.8575581395348837

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd14791	GH36	2.16e-12	337	570	17	238	glycosyl hydrolase family 36 (GH36). GH36 enzymes occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-galactosidase, alpha-N-acetylgalactosaminidase, stachyose synthase, and raffinose synthase. All GH36 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH36 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.
pfam02065	Melibiase	5.43e-10	379	570	93	279	Melibiase. Glycoside hydrolase families GH27, GH31 and GH36 form the glycoside hydrolase clan GH-D. Glycoside hydrolase family 36 can be split into 11 families, GH36A to GH36K. This family includes enzymes from GH36A-B and GH36D-K and from GH27.
pfam16874	Glyco_hydro_36C	7.68e-05	645	711	1	64	Glycosyl hydrolase family 36 C-terminal domain. This domain is found at the C-terminus of many family 36 glycoside hydrolases. It has a beta-sandwich structure with a Greek key motif.
COG3345	GalA	8.76e-04	373	575	331	529	Alpha-galactosidase [Carbohydrate transport and metabolism].
cd14792	GH27	0.002	361	407	34	82	glycosyl hydrolase family 27 (GH27). GH27 enzymes occur in eukaryotes, prokaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-N-acetylgalactosaminidase, and 3-alpha-isomalto-dextranase. All GH27 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH27 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BBO33728.1	6.95e-110	56	725	19	685
BBO33698.1	1.19e-108	66	727	30	688
QUT26597.1	1.88e-104	62	724	30	689
QNL40259.1	1.42e-103	62	724	30	689
QDH53808.1	1.42e-103	62	724	30	689

PDB Hits help

has no PDB hit.

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P16551	3.32e-06	379	570	344	524	Alpha-galactosidase OS=Escherichia coli OX=562 GN=rafA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as LIPO

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000000	0.000000	1.000038	0.000000	0.000000	0.000000

TMHMM Annotations help

There is no transmembrane helices in MGYG000000328_00660.