CAZyme Information: MGYG000000343_00024

Basic Information

• Species: Odoribacter sp900548135
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Marinifilaceae; Odoribacter; Odoribacter sp900548135
• CAZyme ID: MGYG000000343_00024
• CAZy Family: GT51
• CAZyme Description: Penicillin-binding protein 1C

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
781		88218.56	8.3613

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000343	3841231	MAG	Sweden	Europe

• Gene Location: Start: 23131; End: 25476 Strand: +

Full Sequence      

MSLWKIVLIGCLVIGLAWIWWEILPVPLFRVPYSTVLLDKEDEIIGLKTAEDGQLRLQSE
GRLPERYVVAVLSFEDRFFMCHRGVNWWALCRALGQNIRAGKVVSGGSTLSMQVIRLALG
NPPRTLLEKIREILLTVRLEQSYTKEQIIAMYAGHAPFGGNVVGIQAASLKYFNRRPEQL
SWAEAALLAVLPNAPALMYPGKNNESLKRKRDGLLEKIFRQGMMSEDAYRLALAETLPEK
LYDIPGLAPHLLTRAWRDGEGKTFHSYIVKHLQQQVNDIVERHTNLLSQNYIYNVAVLVA
HIPTGEVRAYVGNSVARKGSRGNDVDVIQAARSSGSILKPALYALMLQNGFILPRTLVPD
IPSRFGNYAPSNFNRDFKGAVPAAQALAQSLNIPFVRMLKEYTYARFYDDLKQLGITTLN
RQADHYGLSLILGGGETSLWDVCNMYGGMAAVLRHYNEEDGQYFGGEYRRLKLWENDSNL
GALKEEKKGILKASAIWQTLKALENVERPEMESGWKNFVSAMNLSWKTGTSFGFRDAWAV
GVNPDYVIGVWVGNADGEGRPGLVGIRAAAPILFEVAGLLPSTSQFYEPTEEMQEMVVCR
KSGYRASGLCEETDTVKVCSAGIRTAVCPFHHLIQMDASGKWRVTSDCELVHRMKVKPWF
VLPPVQEWYYCRSHTDYQKLPPYRPDCHPQGEEVMEMIYPQRGTRVFIPRDFGGKPGRVI
FEAVHRFSDALIYWYVDDQYVGVTRNIHQMEIWLQEGSHRLTLMDKGGNLLQQNFQVVGK
D

Enzyme Prediction     

No EC number prediction in MGYG000000343_00024.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT51	61	217	1.6e-47	0.8813559322033898

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
TIGR02073	PBP_1c	0.0	25	778	1	727	penicillin-binding protein 1C. This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG4953	PbpC	1.54e-171	1	768	1	722	Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis].
PRK11240	PRK11240	7.05e-117	3	778	9	772	penicillin-binding protein 1C; Provisional
COG0744	MrcB	1.75e-95	7	575	23	591	Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
TIGR02074	PBP_1a_fam	7.98e-94	63	572	10	520	penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SNV33934.1	0.0	20	781	29	796
ADY32603.1	0.0	20	781	29	796
AZS31892.1	0.0	12	778	14	774
QRO51978.1	0.0	10	778	8	774
BAX81168.1	9.09e-263	11	780	14	789

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3UDF_A	4.77e-28	53	553	36	687	ChainA, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDF_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii]
2OQO_A	3.20e-27	62	233	27	198	Crystalstructure of a peptidoglycan glycosyltransferase from a class A PBP: insight into bacterial cell wall synthesis [Aquifex aeolicus VF5],3D3H_A Crystal structure of a complex of the peptidoglycan glycosyltransferase domain from Aquifex aeolicus and neryl moenomycin A [Aquifex aeolicus],3NB7_A Crystal structure of Aquifex Aeolicus Peptidoglycan Glycosyltransferase in complex with Decarboxylated Neryl Moenomycin [Aquifex aeolicus]
3NB6_A	1.10e-26	62	233	27	198	Crystalstructure of Aquifex aeolicus peptidoglycan glycosyltransferase in complex with Methylphosphoryl Neryl Moenomycin [Aquifex aeolicus]
4OON_A	9.66e-24	63	237	47	221	Crystalstructure of PBP1a in complex with compound 17 ((4Z,8S,11E,14S)-5-(2-amino-1,3-thiazol-4-yl)-14-(5,6-dihydroxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-8-formyl-2-methyl-6-oxo-3,10-dioxa-4,7,11-triazatetradeca-4,11-diene-2,12,14-tricarboxylic acid) [Pseudomonas aeruginosa PAO1]
5FGZ_A	1.54e-23	41	608	141	721	E.coli PBP1b in complex with FPI-1465 [Escherichia coli K-12],5HL9_A E. coli PBP1b in complex with acyl-ampicillin and moenomycin [Escherichia coli K-12],5HLA_A E. coli PBP1b in complex with acyl-cephalexin and moenomycin [Escherichia coli K-12],5HLB_A E. coli PBP1b in complex with acyl-aztreonam and moenomycin [Escherichia coli K-12],5HLD_A E. coli PBP1b in complex with acyl-CENTA and moenomycin [Escherichia coli K-12],6YN0_A Structure of E. coli PBP1b with a FtsN peptide activating transglycosylase activity [Escherichia coli K-12],7LQ6_A Chain A, Penicillin-binding protein 1B [Escherichia coli K-12]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P76577	1.19e-86	25	694	33	688	Penicillin-binding protein 1C OS=Escherichia coli (strain K12) OX=83333 GN=pbpC PE=1 SV=1
P38050	1.73e-36	34	553	48	569	Penicillin-binding protein 1F OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpF PE=2 SV=2
P45345	4.24e-35	25	572	123	696	Penicillin-binding protein 1B OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=mrcB PE=3 SV=1
Q9KUC0	2.16e-32	41	558	165	693	Penicillin-binding protein 1B OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) OX=243277 GN=mrcB PE=3 SV=1
Q89AR2	1.77e-30	37	554	138	667	Penicillin-binding protein 1B OS=Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp) OX=224915 GN=mrcB PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000032	0.000011	0.000002	0.000000	0.000000	0.000001

TMHMM  Annotations     

start	end
7	29