CAZyme Information: MGYG000000348_01946

Basic Information

• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae; CAG-485
• CAZyme ID: MGYG000000348_01946
• CAZy Family: GH88
• CAZyme Description: Unsaturated chondroitin disaccharide hydrolase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
398		45539.4	7.4756

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000348	2655711	MAG	Sweden	Europe

• Gene Location: Start: 14479; End: 15675 Strand: +

Full Sequence      

MLLTSCAGVSAAKLDENKAITYCQNQTWRTLRQVTRNGEDFTLMPRNIANTDSVWTLRKN
SPEEWCNGFWPGVLWYAYESSNDLKLREYAEKYTETLEFLSQRPAFDHDLGFLVFCSYGN
GYRLTHNPRYKQVILATADTLATLFNPNVGTILSWPRNVEMLGGHNTIMDNMINLEMLFW
AAKNGGDHRLYDIAVKHAETTMKHHFRPDNTCYHVAVYDPKTGEFLKGMTHQGYADDSLW
ARGQAWAIYGYTVVYRETRDPKFLDFACKVTDAYLNRLPKDYVPYWDFDDPAGQKAPRDA
SAAAVVASALLELQGYCDKANQERYYKAAQKMLASLSSDKYQSRGKRPSFLDHSTGHKPA
GSEIDASIIYADYYYLEALLRLKRVRGHLDPLGQLAQR

Enzyme Prediction     

No EC number prediction in MGYG000000348_01946.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH88	60	382	1.4e-129	0.9878419452887538

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07470	Glyco_hydro_88	5.30e-19	50	257	14	207	Glycosyl Hydrolase Family 88. Unsaturated glucuronyl hydrolase catalyzes the hydrolytic release of unsaturated glucuronic acids from oligosaccharides (EC:3.2.1.-) produced by the reactions of polysaccharide lyases.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ABR37845.1	5.40e-196	2	385	14	398
QQY39821.1	5.40e-196	2	385	14	398
QEW35632.1	3.11e-195	2	385	14	398
QUT85425.1	8.89e-195	2	385	14	398
QJR69439.1	2.54e-194	2	385	14	398

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3WIW_A	4.10e-89	22	386	31	392	Crystalstructure of unsaturated glucuronyl hydrolase specific for heparin [Pedobacter heparinus DSM 2366]
2ZZR_A	1.03e-60	29	381	34	388	Crystalstructure of unsaturated glucuronyl hydrolase from Streptcoccus agalactiae [Streptococcus agalactiae]
3ANJ_A	1.06e-60	29	381	35	389	Crystalstructure of unsaturated glucuronyl hydrolase from Streptcoccus agalactiae [Streptococcus agalactiae serogroup III]
3WUX_A	1.49e-60	29	381	35	389	Crystalstructure of unsaturated glucuronyl hydrolase mutant D115N/K370S from Streptococcus agalactiae [Streptococcus agalactiae NEM316]
3ANI_A	5.79e-60	29	381	35	389	Crystalstructure of unsaturated glucuronyl hydrolase mutant D175N from Streptcoccus agalactiae [Streptococcus agalactiae serogroup III],3ANK_A Crystal structure of unsaturated glucuronyl hydrolase mutant D175N from Streptcoccus agalactiae complexed with dGlcA-GalNAc6S [Streptococcus agalactiae serogroup III]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
T2KLZ3	5.31e-86	45	381	59	393	Unsaturated glucuronyl hydrolase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21900 PE=1 SV=1
Q9A0T3	3.61e-62	31	381	38	390	Unsaturated chondroitin disaccharide hydrolase OS=Streptococcus pyogenes serotype M1 OX=301447 GN=ugl PE=1 SV=1
Q8DR77	1.99e-60	29	381	33	387	Unsaturated chondroitin disaccharide hydrolase OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) OX=171101 GN=ugl PE=1 SV=1
Q8E372	5.80e-60	29	381	35	389	Unsaturated chondroitin disaccharide hydrolase OS=Streptococcus agalactiae serotype III (strain NEM316) OX=211110 GN=gbs1889 PE=1 SV=1
Q9RC92	3.95e-58	30	394	13	377	Unsaturated glucuronyl hydrolase OS=Bacillus sp. (strain GL1) OX=84635 GN=ugl PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as LIPO

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.260720	0.324849	0.412832	0.000953	0.000316	0.000323

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000348_01946.