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CAZyme Information: MGYG000000354_01808

You are here: Home > Sequence: MGYG000000354_01808

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species CAG-485 sp001701295
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae; CAG-485; CAG-485 sp001701295
CAZyme ID MGYG000000354_01808
CAZy Family GH97
CAZyme Description Glucan 1,4-alpha-glucosidase SusB
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
703 MGYG000000354_24|CGC2 80023.49 5.3071
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000354 2905675 MAG Sweden Europe
Gene Location Start: 42025;  End: 44136  Strand: +

Full Sequence      Download help

MKTSNLVCLL  LLTSIGASAA  ETSISSPSGD  LTVNFGLQRD  GRPEYKVEYK  KQPVVLASGL60
GLELIDSPDL  MSGFEITGTD  TRSFDETWQP  VWGENKNIRN  NYHELLVHLR  QPSTGRLMNI120
RFRVYDDGVG  FRYEFPTQPD  LVYFTVKEEH  TQFAMTGNHI  AWWIAGDYDT  QEYDYTESRL180
SEIRDLMDGS  ISGNASQTQF  SPTGVQTSLQ  LKTDEGIYIN  IHEAALVDYS  TMHLNLDDER240
MVFESWLTPD  AEGDKGHLQA  PCRSPWRTLI  ISDDARDMLA  SNLIYNLNDP  CAYEDTSWIK300
PIKYIGVWWE  MIGGGKQWSY  TSDLPSVKLD  QTDYTKTNPH  GQHPANTENV  KRYIDFAAEH360
GFDQVLVEGW  NVGWEDWFGK  SKDYVFDFVT  PYPDFDIDYL  NEYAHSKGIR  LMMHHETSGA420
TRNYERHMEK  AYQLMEKYGY  NAVKSGYVGN  VMPRGEHHYG  QWLNNHYLYA  VTEAAKHKIM480
VNAHEATRPT  GLARTYPNLV  GNESARGTEY  ESFAGNKPSH  TTVLPFTRLQ  GGPMDYTPGI540
FVMDMKKINP  NSSGHVNSTL  ARQLALYVTM  YSPIQMAADY  PEHYEQHMDA  FQFIKDVAVD600
WDESRYIEAE  PGQYIVVARK  AKNSDEWFVG  CTAAENGHKS  LVSFDFLDPE  RKYEAVIYAD660
APDSHYITNP  ETYKITRKKI  TSKTKLNLRA  APGGGYAISI  KPL703

Enzyme Prediction      help

EC 3.2.1.3 3.2.1.20

CAZyme Signature Domains help

Created with Snap357010514017521024628131635138642145649252756259763266710700GH97
Family Start End Evalue family coverage
GH97 10 700 5.7e-251 0.993660855784469

CDD Domains      download full data without filtering help

Created with Snap3570105140175210246281316351386421456492527562597632667295598Glyco_hydro_9726290GH97_N601701GH97_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam10566 Glyco_hydro_97 1.12e-141 295 598 1 278
Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands.
pfam14508 GH97_N 3.36e-96 26 290 1 235
Glycosyl-hydrolase 97 N-terminal. This N-terminal domain of glycosyl-hydrolase-97 contributes part of the active site pocket. It is also important for contact with the catalytic and C-terminal domains of the whole.
pfam14509 GH97_C 4.11e-42 601 701 1 97
Glycosyl-hydrolase 97 C-terminal, oligomerization. Glycosyl-hydrolase-97 is made up of three tightly linked and highly conserved globular domains. The C-terminal domain is found to be necessary for oligomerization of the whole molecule in order to create the active-site pocket and the Ca++-binding site.

CAZyme Hits      help

Created with Snap35701051401752102462813163513864214564925275625976326677700QUT91746.1|GH971700QBJ16998.1|GH971700QUT99420.1|GH977700ALJ62516.1|GH9724700QUT36784.1|GH97
Hit ID E-Value Query Start Query End Hit Start Hit End
QUT91746.1 0.0 7 700 9 698
QBJ16998.1 0.0 1 700 1 698
QUT99420.1 0.0 1 700 1 698
ALJ62516.1 0.0 7 700 9 698
QUT36784.1 0.0 24 700 22 698

PDB Hits      download full data without filtering help

Created with Snap3570105140175210246281316351386421456492527562597632667187012D73_A247012JKA_A217013WFA_A237035HQ4_A237035HQC_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2D73_A 0.0 18 701 19 724
CrystalStructure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2D73_B Crystal Structure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2ZQ0_A Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron],2ZQ0_B Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron]
2JKA_A 0.0 24 701 14 713
Nativestructure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKA_B Native structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKE_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKE_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKP_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482],2JKP_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482]
3WFA_A 0.0 21 701 2 704
Catalyticrole of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron],3WFA_B Catalytic role of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron]
5HQ4_A 5.42e-159 23 703 2 661
AGlycoside Hydrolase Family 97 enzyme from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8],5HQA_A A Glycoside Hydrolase Family 97 enzyme in complex with Acarbose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]
5HQC_A 5.42e-159 23 703 2 661
AGlycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]

Swiss-Prot Hits      download full data without filtering help

Created with Snap357010514017521024628131635138642145649252756259763266720701sp|G8JZS4|SUSB_BACTN6701sp|Q8A6L0|AGAL_BACTN17642sp|D7CFN7|AGAL_STRBB
Hit ID E-Value Query Start Query End Hit Start Hit End Description
G8JZS4 0.0 20 701 21 724
Glucan 1,4-alpha-glucosidase SusB OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=susB PE=1 SV=1
Q8A6L0 2.89e-58 6 701 8 662
Retaining alpha-galactosidase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_1871 PE=1 SV=1
D7CFN7 3.95e-34 17 642 30 572
Probable retaining alpha-galactosidase OS=Streptomyces bingchenggensis (strain BCW-1) OX=749414 GN=SBI_01652 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000381 0.998732 0.000234 0.000217 0.000211 0.000196

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000354_01808.