CAZyme Information: MGYG000000360_00701

Basic Information

• Species: UBA1829 sp900548385
• Lineage: Bacteria; Verrucomicrobiota; Lentisphaeria; Victivallales; UBA1829; UBA1829; UBA1829 sp900548385
• CAZyme ID: MGYG000000360_00701
• CAZy Family: CBM9
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
876		97971.45	8.8608

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000360	4492877	MAG	Sweden	Europe

• Gene Location: Start: 908577; End: 911207 Strand: -

Full Sequence      

MKRLFLSALLCIGLLIPSVIQAGRKTIPVIKDAAFSLERNYSDFTSLPRITLHNKGKDEK
IFELFSTLTDTDGRIIRSARTRLSAPAGGKATVAPFPGESKIRGQVVLFRTDVKGTDGST
HLSGIFGESRPVPRNSANVFGMNVHTSWFDPDVQWELLRMLKAAGITTVREDTTFRDPED
TKGIERTVRQQLETVLAMEAFGIEPLVMIAWFPKGFQNSPQKLERAYKWAEFLAKELKGR
VDFHYGNETNSGWGAFGTAADMGPLNAAFALGTKAGDPGAPRASFGIAEGLNNYIREFIK
TGVMEHLEALCIHPYCGTPEAGIAKSIAAKELLRKNGSNAQIWATEIGFHFEKDGKLNQQ
TGELTGVAGYSKQDQENFLPRLYILAQSHGIERIYWYDFFGRNDPETFWIVDENFQPLGA
YHALKECSRQLAGTRPAGGTRYDELIQKHLFIRPDGTSLLAVWSTQGERKADFKLSATVR
ITDKTGKQIRLPADGVLSLNESVCYIEGLPLSRFYRNDVLCNALDKRIFMLPSHRFTLKP
GATVEIPWTVFNSSAVPVQARPALLSTNPGWKLEFPANETVPAHGTRNGRFRLTAPADAV
PGTEYEFTFAADLDVIQRTRPYTVRVYVEGAFPYHAIAAHSKTVDYPMWNSMDERQTKKG
NPMLTASYGNAVVDGNLSEWKKEEFHPIDQKFQWIQRDPGQPSDQDWSGKVAFRWDERNL
YAAFLVEDDQLSFLDFSSRDWRESDNMRLFLSSIPDAAKRTKTISRNDLLLIMAPTGKSR
TENARLKAAPLGGLPRPGVEKQIPVAARMWKNGYVLEVAVPFSIFNAKPEAGTFLGMNVM
ADDIDDGYRQHVGMTYYANPSYWNSPKALGSLKLVR

Enzyme Prediction     

No EC number prediction in MGYG000000360_00701.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
CBM9	673	874	5.2e-18	0.9945054945054945

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd09619	CBM9_like_4	7.77e-24	670	870	1	187	DOMON-like type 9 carbohydrate binding module. Family 9 carbohydrate-binding modules (CBM9) play a role in the microbial degradation of cellulose and hemicellulose (materials found in plants). The domain has previously been called cellulose-binding domain. The polysaccharide binding sites of CBMs with available 3D structure have been found to be either flat surfaces with interactions formed by predominantly aromatic residues (tryptophan and tyrosine), or extended shallow grooves. CBM9 domains found in this uncharacterized heterogeneous subfamily are often located at the C-terminus of longer proteins and may co-occur with various other domains.
pfam06452	CBM9_1	1.18e-12	673	875	1	182	Carbohydrate family 9 binding domain-like. CBM9_1 is a C-terminal domain on bacterial xylanase proteins, and it is tandemly repeated in a number of family-members. The CBM9 module binds to amorphous and crystalline cellulose and a range of soluble di- and monosaccharides as well as to cello- and xylo- oligomers of different degrees of polymerization. Comparison of the glucose and cellobiose complexes during crystallisation reveals surprising differences in binding of these two substrates by CBM9-2. Cellobiose was found to bind in a distinct orientation from glucose, while still maintaining optimal stacking and electrostatic interactions with the reducing end sugar.
cd00005	CBM9_like_1	2.10e-07	665	875	3	185	DOMON-like type 9 carbohydrate binding module of xylanases. Family 9 carbohydrate-binding modules (CBM9) play a role in the microbial degradation of cellulose and hemicellulose (materials found in plants). The domain has previously been called cellulose-binding domain. The polysaccharide binding sites of CBMs with available 3D structure have been found to be either flat surfaces with interactions formed by predominantly aromatic residues (tryptophan and tyrosine), or extended shallow grooves. The CBM9 domain frequently occurs in tandem repeats; members found in this subfamily typically co-occur with glycosyl hydrolase family 10 domains and are annotated as endo-1,4-beta-xylanases. CBM9 from Thermotoga maritima xylanase 10A is reported to have specificity for polysaccharide reducing ends.
cd00241	DOMON_like	4.68e-07	690	851	1	154	Domon-like ligand-binding domains. DOMON-like domains can be found in all three kindgoms of life and are a diverse group of ligand binding domains that have been shown to interact with sugars and hemes. DOMON domains were initially thought to confer protein-protein interactions. They were subsequently found as a heme-binding motif in cellobiose dehydrogenase, an extracellular fungal oxidoreductase that degrades both lignin and cellulose, and in ethylbenzene dehydrogenase, an enzyme that aids in the anaerobic degradation of hydrocarbons. The domain interacts with sugars in the type 9 carbohydrate binding modules (CBM9), which are present in a variety of glycosyl hydrolases, and it can also be found at the N-terminus of sensor histidine kinases.
pfam10633	NPCBM_assoc	9.63e-05	538	611	1	75	NPCBM-associated, NEW3 domain of alpha-galactosidase. The English-language version of the first reference can be found on pages 388-399 of the above. This domain has been named NEW3 but its actual function is not known. It is found on proteins which are bacterial galactosidases. The domain is associated with the NPCBM family, pfam08305, a novel putative carbohydrate binding module found at the N-terminus of glycosyl hydrolases.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SDU11835.1	5.87e-227	1	875	1	870
AHF92009.1	1.40e-212	43	875	8	867
AHF90983.1	6.04e-207	1	875	1	907
AZS14136.1	1.82e-17	129	486	416	786
QNK56522.1	4.46e-15	132	508	687	1079

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000306	0.999001	0.000197	0.000163	0.000150	0.000136

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000360_00701.