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CAZyme Information: MGYG000000360_02924
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | UBA1829 sp900548385 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Verrucomicrobiota; Lentisphaeria; Victivallales; UBA1829; UBA1829; UBA1829 sp900548385 | |||||||||||
| CAZyme ID | MGYG000000360_02924 | |||||||||||
| CAZy Family | GT9 | |||||||||||
| CAZyme Description | ADP-heptose--LPS heptosyltransferase 2 | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 23665; End: 24762 Strand: - | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| TIGR02195 | heptsyl_trn_II | 6.44e-47 | 32 | 365 | 2 | 333 | lipopolysaccharide heptosyltransferase II. This family consists of examples of ADP-heptose:LPS heptosyltransferase II, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
| cd03789 | GT9_LPS_heptosyltransferase | 7.59e-46 | 32 | 362 | 2 | 276 | lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
| COG0859 | RfaF | 4.60e-43 | 32 | 359 | 4 | 324 | ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis]. |
| pfam01075 | Glyco_transf_9 | 1.22e-28 | 220 | 344 | 119 | 244 | Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core. |
| PRK10916 | PRK10916 | 2.03e-20 | 220 | 331 | 195 | 314 | ADP-heptose--LPS heptosyltransferase RfaF. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AVM44431.1 | 2.80e-118 | 16 | 357 | 45 | 386 |
| QSH42308.1 | 3.59e-117 | 9 | 357 | 8 | 356 |
| QSR85609.1 | 3.09e-54 | 32 | 365 | 6 | 321 |
| QSR89503.1 | 8.92e-52 | 29 | 357 | 7 | 318 |
| QIF00771.1 | 4.42e-50 | 32 | 365 | 332 | 653 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1PSW_A | 1.30e-23 | 32 | 331 | 3 | 314 | Structureof E. coli ADP-heptose lps heptosyltransferase II [Escherichia coli] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P45042 | 9.41e-28 | 32 | 326 | 3 | 304 | ADP-heptose--LPS heptosyltransferase 2 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=rfaF PE=3 SV=1 |
| P37692 | 4.65e-26 | 32 | 331 | 3 | 314 | ADP-heptose--LPS heptosyltransferase 2 OS=Escherichia coli (strain K12) OX=83333 GN=rfaF PE=1 SV=1 |
| P37421 | 1.22e-25 | 32 | 331 | 3 | 314 | ADP-heptose--LPS heptosyltransferase 2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfaF PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.999998 | 0.000031 | 0.000002 | 0.000000 | 0.000000 | 0.000000 |