CAZyme Information: MGYG000000390_00138

Basic Information

• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae
• CAZyme ID: MGYG000000390_00138
• CAZy Family: GH2
• CAZyme Description: Beta-galactosidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
999	MGYG000000390_6|CGC1	111446.54	5.2233

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000390	2232010	MAG	Sweden	Europe

• Gene Location: Start: 12480; End: 15479 Strand: -

Full Sequence      

MPEQDYFAQIAMTKHPMRTDDKEFPPLPLPKAVFSPSGDVCPPVPEPTFDQRMESFRRDL
SAMRSYYQPFMRDLLPDFAEQEETQELKTFSFRYAAPKEMFMGSLPEEGNWETVTVPDYR
GPAAKWKGFYRTTFSLRPLEAGEQAVIRFASVDYRAVVYCNGVCVGSHEGFFAPFEVNIT
DCLQPVNTLVVEVHNDVSILGQGPVLDGDKIYAATGPGWDDPELGWHHCPAGAGILDSVV
VALCPSIRITDLFVRPNIDGHYAEIRMGVQNDTGTVAEGYDLTLRALPKNYEGDAIGALT
ASVPYIGVGQNEYRFAMALQGERLWEPDTPWLYGLQAELSQNGPVSRRVGTFGMRKFISD
EQSEPKGKFYFNNRPIVLRGANEMGHLQQCVMKGDDDQLIDDILIAKLCHMNYYRVTQRP
VQKKIYDYFDMLGMMHQCDLPLFSFLRRNQACEAIKQAAELEHLIRSHPSSILVSLINEP
MSIRCTQDPNDKYSKRYQQKGHRHLLRDELEAFFAAARKAIYIENPDRVVKNAEGDYDPP
TMEGLPDFHCYTMWYSNHAMPIGKLYKGYLPPVKRGWMIGCGEYGAEGLDNDSVMRKYYP
KEWLAPNADGTWYPDRISHSQTFSVQGDWYPEQTGRQDWIFESQKHQANATATMTDAFRR
RADLISHTAIHLLIDAWPAGWMKTLLDVDRQPKPAYFAYADSLVPFRVNLRCDRNAWYEG
ETVMVEAWLLNDTAEEKRGELVATVTQDGKVIASYALQAQVGAATAVCAGLIPVTAPAVE
SAAPLRVALGFRGQDGAFESLEKKDFTIYPLRVHAVPVACLGETAVQTASSLRLPVVDPE
QAAAFLVSSADEADLRQAASWAETGKTVMVLLPDAPCDWQVGGVRLATKGCGPVFFAAAA
PEAEPYRLTMLYNSQEDYIDFSGTHTIETQANGRDLLYTYSKQGLSGAHGAKAHLPFVKE
IPCGRGKLIAVSLPLSGRLSVNPNLDAFLTGCLAGTLGQ

Enzyme Prediction     

No EC number prediction in MGYG000000390_00138.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	109	764	2.4e-65	0.6409574468085106

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3250	LacZ	1.07e-23	91	762	20	679	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10150	PRK10150	4.75e-15	118	482	62	420	beta-D-glucuronidase; Provisional
PRK10340	ebgA	1.45e-12	128	479	111	449	cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam00703	Glyco_hydro_2	1.83e-07	247	355	1	106	Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
pfam02837	Glyco_hydro_2_N	4.64e-06	111	195	55	135	Glycosyl hydrolases family 2, sugar binding domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ALL53566.1	0.0	1	989	1	997
QOV20252.1	0.0	4	997	3	1016
AEI43263.1	7.84e-313	2	993	7	1010
AFC30919.1	2.22e-312	2	993	7	1010
AFH63244.2	4.46e-312	2	993	7	1010

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6ED2_A	8.05e-17	129	495	94	454	ChainA, Glycosyl hydrolase family 2, TIM barrel domain protein [Faecalibacterium duncaniae]
7SF2_A	2.20e-16	130	441	90	378	ChainA, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_B Chain B, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_C Chain C, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_D Chain D, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_E Chain E, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_F Chain F, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838]
6U7I_A	1.19e-15	129	498	67	431	Faecalibacteriumprausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii],6U7I_B Faecalibacterium prausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii],6U7I_C Faecalibacterium prausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii],6U7I_D Faecalibacterium prausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii]
7KGY_A	7.71e-14	129	502	72	439	ChainA, Beta-glucuronidase [Faecalibacterium prausnitzii],7KGY_B Chain B, Beta-glucuronidase [Faecalibacterium prausnitzii],7KGY_C Chain C, Beta-glucuronidase [Faecalibacterium prausnitzii],7KGY_D Chain D, Beta-glucuronidase [Faecalibacterium prausnitzii]
6LD0_A	1.94e-13	126	480	67	482	ChainA, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD0_B Chain B, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD0_C Chain C, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD0_D Chain D, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD6_A Chain A, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD6_B Chain B, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD6_C Chain C, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD6_D Chain D, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDB_A Chain A, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDB_B Chain B, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDB_C Chain C, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDB_D Chain D, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDC_A Chain A, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDC_B Chain B, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDC_C Chain C, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDC_D Chain D, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDD_A Chain A, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDD_B Chain B, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDD_C Chain C, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDD_D Chain D, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P77989	2.23e-13	107	481	28	390	Beta-galactosidase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=lacZ PE=3 SV=2
B4S2K9	4.70e-13	122	479	116	460	Beta-galactosidase OS=Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype) OX=1774373 GN=lacZ PE=3 SV=1
P06760	3.91e-09	140	589	114	542	Beta-glucuronidase OS=Rattus norvegicus OX=10116 GN=Gusb PE=1 SV=1
O18835	3.92e-09	140	589	114	545	Beta-glucuronidase OS=Canis lupus familiaris OX=9615 GN=GUSB PE=1 SV=1
P12265	5.15e-09	144	559	118	508	Beta-glucuronidase OS=Mus musculus OX=10090 GN=Gusb PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000055	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000390_00138.