CAZyme Information: MGYG000000392_00319

Basic Information

• Species: Ruminococcus_E sp003521625
• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; Ruminococcus_E; Ruminococcus_E sp003521625
• CAZyme ID: MGYG000000392_00319
• CAZy Family: CBM74
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1027		110691.6	4.6373

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000392	2042501	MAG	Sweden	Europe

• Gene Location: Start: 346430; End: 349513 Strand: -

Full Sequence      

MKSTRKAISVILTVLMLITCVSVSFTVNASTGTLCDKYATNPQGKIGVKKTITIDGSYSD
WSSDMLIAQGAAWDVANHYKGGHENCVLDTYALYAAWDDNNLYVAWQMVNTTDTWAREGD
GPLSDGGRVLDVPLILALSVDPSSTSMSNKNTNGDPIWGRKMGLTFNQHVDHLLYMSGKV
GNGTPGMFTAVDEQGNTNYTNGLKTFKDNGIEYKMAEGNVCDSIIGLNYSEDTSDVYSND
ADWVDYKTFKGSSGTHNTKYDSFYEIKIPLSTLGINSSYIENNGLGAMVVATRGESGLDC
IPFDDTMLDNTTGSYGSDASTSHEKDDEDVITSSFARIGNLGGDVPVTQPTTAKPTTQPT
TAKPTTQPTTAKPTIQPTTAKTTTQPTTAKTTTTPVSNTLTVNAKSNLFATNTVKADSNA
KTVTVSYDLQSSMKLVNSQWSLSYDNTKLKLVSTSNDLMPNVTDGVVNFMDGIVKGNFTN
VTKLYDFTSSKPFVKATFEIIGSGSTDVTLNVQELSVGYKSNNSLVYKNAVVNSIKQDLS
GISGFESSSITGSASAVTDVQPTTVLPTQATTAKPTQATTQQPTTAASSLTVNATSNFFP
AASKTYSSSEKQVTVSYKLSSAMKLINSEWELEYDTSKLSFNSANIGNLMPNVSSAVIYE
NTKGKIKGNFTTASLVDFSNESDFVSITFDVIGKGTADVNLFVKVLGVAYKKFGSTPTIA
YVVDFGEIKDVTSIPGFEKETYTVKTVFDPQTTPTTVPVTTNPTVPTTKPTEPTTKPTEP
TTKPTEPTTVPVTDTLKVNATSNILPPVSQEYDKDTSTVTVSYKLTSSMKFVNSQWCLTY
DSSKLSYDPQKNPDGVMPNVSSAVINTDLNNRIKGGFSSLSLYDFTTEKDFVTVTFDIIG
TGETTIDLDIEILGVAYKDSNFNVIKAYPVDDSKFIDITSTPGFENMKLSGRITLNEPTE
HIFYGDVNYDGVVNVADATLVQKHAANIVKLTDDQIKRADVNFDGAVNVQDSTLICKFAI
GIISSFK

Enzyme Prediction     

No EC number prediction in MGYG000000392_00319.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
CBM74	38	337	8.4e-76	0.9967948717948718

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd14256	Dockerin_I	2.23e-17	964	1018	1	55	Type I dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type I dockerins, which are responsible for anchoring a variety of enzymatic domains to the complex.
pfam00404	Dockerin_1	2.41e-09	965	1015	1	51	Dockerin type I repeat. The dockerin repeat is the binding partner of the cohesin domain pfam00963. The cohesin-dockerin interaction is the crucial interaction for complex formation in the cellulosome. The dockerin repeats, each bearing homology to the EF-hand calcium-binding loop bind calcium.
cd14253	Dockerin	3.51e-09	965	1019	1	55	Dockerin repeat domain. Dockerins are modules in the cellulosome complex that often anchor catalytic subunits by binding to cohesin domains of scaffolding proteins. Three types of dockerins and their corresponding cohesin have been described in the literature. This alignment models two consecutive dockerin repeats, the functional unit.
cd14254	Dockerin_II	2.54e-07	965	1015	1	49	Type II dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type II dockerins, which are responsible for mediating attachment of the cellulosome complex to the bacterial cell wall.
cd14252	Dockerin_like	2.23e-05	965	1018	1	55	Dockerin repeat domains and domains resembling dockerin repeats. Dockerins are modules in the cellulosome complex that often anchor catalytic subunits by binding to cohesin domains of scaffolding proteins. Three types of dockerins and their corresponding cohesin have been described in the literature. This alignment models two consecutive dockerin repeats, the functional unit.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QCT07491.1	5.38e-159	37	352	224	538
AWX97480.1	7.03e-122	38	339	763	1061
AWX95531.1	7.03e-122	38	339	763	1061
QZS61962.1	4.10e-119	65	339	1	275
CDM67953.1	1.05e-56	32	346	772	1091

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000819	0.614169	0.384053	0.000413	0.000274	0.000228

TMHMM  Annotations     

start	end
7	29