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CAZyme Information: MGYG000000393_00849
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; UBA932; RC9; | |||||||||||
| CAZyme ID | MGYG000000393_00849 | |||||||||||
| CAZy Family | GH89 | |||||||||||
| CAZyme Description | Beta-hexosaminidase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 1237; End: 5919 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH89 | 66 | 705 | 1.1e-206 | 0.9788838612368024 |
| GH3 | 804 | 1024 | 1.2e-61 | 0.9768518518518519 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam05089 | NAGLU | 2.58e-148 | 125 | 444 | 1 | 331 | Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This central domain has a tim barrel fold. |
| PRK15098 | PRK15098 | 5.65e-143 | 731 | 1450 | 35 | 758 | beta-glucosidase BglX. |
| pfam12972 | NAGLU_C | 7.84e-90 | 454 | 703 | 1 | 249 | Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This C-terminal domain has an all alpha helical fold. |
| PLN03080 | PLN03080 | 4.19e-84 | 807 | 1444 | 78 | 770 | Probable beta-xylosidase; Provisional |
| COG1472 | BglX | 2.18e-80 | 741 | 1165 | 1 | 397 | Periplasmic beta-glucosidase and related glycosidases [Carbohydrate transport and metabolism]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| BBL07501.1 | 0.0 | 21 | 1560 | 23 | 1563 |
| ALO49402.1 | 0.0 | 27 | 1555 | 33 | 1557 |
| QUB47602.1 | 0.0 | 1 | 1555 | 1 | 1549 |
| QIL38350.1 | 2.81e-280 | 721 | 1534 | 25 | 838 |
| QNL52448.1 | 1.06e-256 | 711 | 1556 | 15 | 860 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5YOT_A | 8.36e-144 | 720 | 1450 | 4 | 749 | Isoprimeverose-producingenzyme from Aspergillus oryzae in complex with isoprimeverose [Aspergillus oryzae RIB40],5YOT_B Isoprimeverose-producing enzyme from Aspergillus oryzae in complex with isoprimeverose [Aspergillus oryzae RIB40],5YQS_A Isoprimeverose-producing enzyme from Aspergillus oryzae in complex with isoprimeverose [Aspergillus oryzae RIB40],5YQS_B Isoprimeverose-producing enzyme from Aspergillus oryzae in complex with isoprimeverose [Aspergillus oryzae RIB40] |
| 7EAP_A | 5.99e-143 | 720 | 1450 | 4 | 749 | ChainA, Fn3_like domain-containing protein [Aspergillus oryzae RIB40] |
| 2VC9_A | 3.51e-138 | 30 | 702 | 174 | 860 | Family89 Glycoside Hydrolase from Clostridium perfringens in complex with 2-acetamido-1,2-dideoxynojirmycin [Clostridium perfringens],2VCA_A Family 89 glycoside hydrolase from Clostridium perfringens in complex with beta-N-acetyl-D-glucosamine [Clostridium perfringens],2VCB_A Family 89 Glycoside Hydrolase from Clostridium perfringens in complex with PUGNAc [Clostridium perfringens],2VCC_A Family 89 Glycoside Hydrolase from Clostridium perfringens [Clostridium perfringens] |
| 7MFK_A | 4.32e-138 | 30 | 702 | 182 | 868 | ChainA, Alpha-N-acetylglucosaminidase family protein [Clostridium perfringens ATCC 13124],7MFL_A Chain A, Alpha-N-acetylglucosaminidase family protein [Clostridium perfringens ATCC 13124] |
| 4A4A_A | 4.47e-137 | 30 | 702 | 197 | 883 | CpGH89(E483Q, E601Q), from Clostridium perfringens, in complex with its substrate GlcNAc-alpha-1,4-galactose [Clostridium perfringens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| T2KMH0 | 1.91e-119 | 807 | 1446 | 62 | 710 | Beta-xylosidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22130 PE=1 SV=1 |
| Q9FNA3 | 1.09e-105 | 28 | 721 | 47 | 806 | Alpha-N-acetylglucosaminidase OS=Arabidopsis thaliana OX=3702 GN=NAGLU PE=2 SV=1 |
| Q56078 | 7.59e-103 | 731 | 1450 | 35 | 758 | Periplasmic beta-glucosidase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=bglX PE=3 SV=2 |
| P54802 | 2.90e-102 | 30 | 721 | 32 | 736 | Alpha-N-acetylglucosaminidase OS=Homo sapiens OX=9606 GN=NAGLU PE=1 SV=2 |
| T2KMH9 | 3.99e-102 | 723 | 1452 | 29 | 750 | Putative beta-xylosidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22230 PE=2 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000240 | 0.999193 | 0.000165 | 0.000141 | 0.000131 | 0.000127 |