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CAZyme Information: MGYG000000398_01651

You are here: Home > Sequence: MGYG000000398_01651

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; TF01-11;
CAZyme ID MGYG000000398_01651
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
358 MGYG000000398_10|CGC1 39500.13 9.6278
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000398 2936252 MAG Sweden Europe
Gene Location Start: 90334;  End: 91410  Strand: -

Full Sequence      Download help

MKKIVLTGGG  TAGHVTPNIA  LIPELQKQGY  EVHYIGSYEG  IESRLIPELG  IPYYGISSGK60
LRRYIDPKNL  SDPFKVIRGY  SQARKLLKII  HPDVVFSKGG  FVSVPVVVAA  KSRHIPCVIH120
ESDMTPGLAN  KICIPCADRV  CTNFPETLKH  LPEHKGVLTG  SPIRQELFRG  SKEKGLAFCG180
FTGEKPVILI  IGGSLGAVRV  NEAVRAILPQ  LLERFQIIHL  CGKGKMDDSL  KDTKGYVQFE240
YIKEELRDLM  AAADIMISRA  GANAICEILA  LRKPNILIPL  SAQASRGDQI  LNAASFEKQG300
YSIVIQEEDL  TNEKLLNAVN  TAFNEKERFI  KAMQRSQLNN  SIEKIVELIN  VSAKNKKK358

Enzyme Prediction      help

No EC number prediction in MGYG000000398_01651.

CAZyme Signature Domains help

Created with Snap1735537189107125143161179196214232250268286304322340188337GT28
Family Start End Evalue family coverage
GT28 188 337 8.1e-44 0.9426751592356688

CDD Domains      download full data without filtering help

Created with Snap17355371891071251431611791962142322502682863043223401350PRK124461349murG3348GT28_MurG2354MurG2349murG
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK12446 PRK12446 4.80e-154 1 350 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed
PRK00726 murG 2.20e-151 1 349 1 351
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 3.70e-128 3 348 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 7.80e-121 2 354 1 356
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 6.29e-105 2 349 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]

CAZyme Hits      help

Created with Snap17355371891071251431611791962142322502682863043223401349QHQ60226.1|GT281354BCN32922.1|GT281349ABX44074.1|GT281349BBF44674.1|GT281349BCJ92484.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
QHQ60226.1 5.29e-180 1 349 1 349
BCN32922.1 3.54e-178 1 354 1 354
ABX44074.1 1.05e-177 1 349 1 349
BBF44674.1 1.44e-177 1 349 1 349
BCJ92484.1 1.67e-176 1 349 1 349

PDB Hits      download full data without filtering help

Created with Snap173553718910712514316117919621423225026828630432234032803S2U_A23497D1I_A23191F0K_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3S2U_A 1.08e-40 3 280 4 280
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
7D1I_A 4.08e-40 2 349 10 362
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
1F0K_A 5.99e-37 2 319 7 319
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Created with Snap17355371891071251431611791962142322502682863043223401349sp|A9KK83|MURG_LACP71354sp|C4Z1B5|MURG_LACE21349sp|B1KYH7|MURG_CLOBM1349sp|A7GGX9|MURG_CLOBL1349sp|B1IKH3|MURG_CLOBK
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A9KK83 2.10e-178 1 349 1 349
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Lachnoclostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) OX=357809 GN=murG PE=3 SV=1
C4Z1B5 2.01e-171 1 354 1 354
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Lachnospira eligens (strain ATCC 27750 / DSM 3376 / VPI C15-48 / C15-B4) OX=515620 GN=murG PE=3 SV=1
B1KYH7 6.64e-151 1 349 1 349
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Clostridium botulinum (strain Loch Maree / Type A3) OX=498214 GN=murG PE=3 SV=1
A7GGX9 9.43e-151 1 349 1 349
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Clostridium botulinum (strain Langeland / NCTC 10281 / Type F) OX=441772 GN=murG PE=3 SV=1
B1IKH3 9.43e-151 1 349 1 349
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Clostridium botulinum (strain Okra / Type B1) OX=498213 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000076 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000398_01651.