CAZyme Information: MGYG000000400_02260

Basic Information

• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae; UBA7173
• CAZyme ID: MGYG000000400_02260
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
938		105374.63	4.756

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000400	2908659	MAG	Sweden	Europe

• Gene Location: Start: 4108; End: 6924 Strand: +

Full Sequence      

MKKIFSIVTAVVLAIASSAQTAQSVVRLEPEKFCVVVPEGECGPVRLAAEALCRDFGKVT
GYTPEIAAQAPAGAVALIVVNDDTEGAAAETAAPDRLEGFESHSVTADAARSMIVMHGAD
MRGTIYAIYSFSEKILGVPPLWYWCDWAPEHRDVIEVPADYSYSCGSPDVRYRAWFPNDE
DLFVPWRKKSTGNNEMWLETMLRLKLNTVEYTATVTTSGTLNSEAMLYKKYGLVLTSHHM
VALNNSFANWEAYWRDVRHTSVPALSVKDLKSLKEFWQYSIDAVKESGVENLWQIAFRGK
TDQPFWSVFTDAPATDAERGRVISDMVKVQYDMICESTGEKNPFVRMTFYDEISSLLAKG
YIEPPAASNMLWTFVAGRRDHYPYDDLVAWENTGGVQLGYYMNLQFYSTGAHLAPAEGPW
KMEANYRYVMGKGPLTFSVVNAGNLREFLMEMSANAAMMWDAQAYTTDAFLRDFCALYFG
EEHADEAVELYRDFYNSYWNQKTPDFPGGFPRQYIFQDLRHSQVIKMIYNTWNTFKENPL
TEIGYESVPGRTFRIEGDSQVDAMLEGLAREAVDFGDVAARCDALIKKLDSDKSVFFYDH
LGAYATYMANLAEATYRFVHAYKYKESRYADLIASLAAMKSAKKALTDSEHGVFEGWYDT
DDKFEMDRRIEMIAALVPDSEDLTLTERLIKNYDFELNHDGKPNPSGIVRGIPYGWESEG
TLRKGANGLDSYGINQDAKNFHGNNVCWINSVPMPEKFTLYQTIPASELEPGTYRVACKL
WVEVGRKTNCRLFANDNVQYFGYDTDYTNLLTPGEINTYAGYPGGNTSDIVLRDMEVEVK
VDAGEDLTIGIKSGNRMNNGTTATNNAGWFKVDFFRIHKLEGSGVEAVVPDGLQPMNGSD
EDTTIYNLHGQCVGHGAADYSRLQPGVYVMSGRKLLKH

Enzyme Prediction     

No EC number prediction in MGYG000000400_02260.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	34	531	9.6e-48	0.6441893830703013

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	5.62e-41	166	496	1	325	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUT26791.1	2.93e-253	13	676	37	706
QUR45017.1	1.45e-248	13	676	18	687
QUT44996.1	9.47e-230	28	676	28	682
QRQ50325.1	1.01e-228	28	676	6	660
QCR24645.1	1.09e-187	44	661	45	670

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7PUG_A	7.01e-19	27	505	11	513	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
7PXQ_A	3.26e-17	27	505	10	512	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
4C90_A	4.58e-15	114	503	143	526	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
6NPS_A	6.47e-15	45	336	32	337	Crystalstructure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112],6NPS_B Crystal structure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112]
4ZMH_A	1.74e-11	114	505	116	498	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000303	0.999030	0.000208	0.000154	0.000153	0.000144

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000400_02260.