dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000000428_00795

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Basic Information help

Species

Lineage

Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-552; UMGS1795;

CAZyme ID

MGYG000000428_00795

CAZy Family

GH2

CAZyme Description

Beta-glucuronidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
572	MGYG000000428_22\|CGC1	66231.7	4.7165

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000428	1789472	MAG	Sweden	Europe

Gene Location

Start: 18242; End: 19960 Strand: -

Full Sequence Download help

Enzyme Prediction help

No EC number prediction in MGYG000000428_00795.

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GH2	12	455	1.1e-92	0.511968085106383

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK10150	PRK10150	1.51e-44	19	396	13	417	beta-D-glucuronidase; Provisional
COG3250	LacZ	5.62e-32	21	546	15	549	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10340	ebgA	5.60e-14	13	396	33	449	cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam02837	Glyco_hydro_2_N	1.97e-12	21	126	4	121	Glycosyl hydrolases family 2, sugar binding domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction.
pfam00703	Glyco_hydro_2	1.75e-10	179	274	2	106	Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AIQ16879.1	2.30e-205	5	572	9	582
SMF87854.1	2.64e-204	3	572	7	582
ALS26546.1	4.60e-204	3	572	9	587
QOS82722.1	9.95e-204	3	572	4	580
ANY74929.1	2.46e-202	3	572	7	582

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7SF2_A	3.03e-78	7	567	28	587	ChainA, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_B Chain B, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_C Chain C, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_D Chain D, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_E Chain E, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_F Chain F, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838]
6ECA_A	1.67e-31	21	409	43	458	Lactobacillusrhamnosus Beta-glucuronidase [Lacticaseibacillus rhamnosus],6ECA_B Lactobacillus rhamnosus Beta-glucuronidase [Lacticaseibacillus rhamnosus]
3K4A_A	2.66e-31	21	481	17	508	Crystalstructure of selenomethionine substituted E. coli beta-glucuronidase [Escherichia coli K-12],3K4A_B Crystal structure of selenomethionine substituted E. coli beta-glucuronidase [Escherichia coli K-12]
4JHZ_A	4.75e-31	21	481	17	508	Structureof E. coli beta-Glucuronidase bound with a novel, potent inhibitor 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-N-[(1S,2S,5S)-2,5-dimethoxycyclohexyl]acetamide [Escherichia coli K-12],4JHZ_B Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-N-[(1S,2S,5S)-2,5-dimethoxycyclohexyl]acetamide [Escherichia coli K-12]
6JZ1_A	4.75e-31	12	426	11	447	Apostructure of b-glucuronidase from Ruminococcus gnavus at 1.7 Angstrom resolution [[Ruminococcus] gnavus],6JZ1_B Apo structure of b-glucuronidase from Ruminococcus gnavus at 1.7 Angstrom resolution [[Ruminococcus] gnavus],6JZ5_A b-glucuronidase from Ruminococcus gnavus in complex with D-glucuronic acid [[Ruminococcus] gnavus],6JZ5_B b-glucuronidase from Ruminococcus gnavus in complex with D-glucuronic acid [[Ruminococcus] gnavus],6JZ6_A b-glucuronidase from Ruminococcus gnavus in complex with C6-substituted uronic isofagomine [[Ruminococcus] gnavus],6JZ6_B b-glucuronidase from Ruminococcus gnavus in complex with C6-substituted uronic isofagomine [[Ruminococcus] gnavus],6JZ7_A b-glucuronidase from Ruminococcus gnavus in complex with N1-substituted uronic isofagomine [[Ruminococcus] gnavus],6JZ7_B b-glucuronidase from Ruminococcus gnavus in complex with N1-substituted uronic isofagomine [[Ruminococcus] gnavus],6JZ8_A b-glucuronidase from Ruminococcus gnavus in complex with D-glucaro 1,5-lactone [[Ruminococcus] gnavus],6JZ8_B b-glucuronidase from Ruminococcus gnavus in complex with D-glucaro 1,5-lactone [[Ruminococcus] gnavus]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
T2KPJ7	2.20e-31	73	486	106	522	Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21970 PE=2 SV=1
P05804	1.14e-29	21	481	15	506	Beta-glucuronidase OS=Escherichia coli (strain K12) OX=83333 GN=uidA PE=1 SV=2
P77989	4.68e-28	67	450	53	438	Beta-galactosidase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=lacZ PE=3 SV=2
O18835	1.57e-24	10	426	33	478	Beta-glucuronidase OS=Canis lupus familiaris OX=9615 GN=GUSB PE=1 SV=1
O97524	4.94e-24	10	426	33	478	Beta-glucuronidase OS=Felis catus OX=9685 GN=GUSB PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000041	0.000002	0.000000	0.000000	0.000000	0.000000

TMHMM Annotations help

There is no transmembrane helices in MGYG000000428_00795.