CAZyme Information: MGYG000000430_01088

Basic Information

• Species: CAG-1000 sp900761555
• Lineage: Bacteria; Firmicutes; Bacilli; RF39; UBA660; CAG-1000; CAG-1000 sp900761555
• CAZyme ID: MGYG000000430_01088
• CAZy Family: GT51
• CAZyme Description: Monofunctional biosynthetic peptidoglycan transglycosylase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
918		102547.76	8.6884

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000430	1166774	MAG	Sweden	Europe

• Gene Location: Start: 42182; End: 44938 Strand: +

Full Sequence      

MKKFRKKSNDEDTPKKKHKFRFGYWFLVFIVTFAILCFVAGIGFCYYIVKSAPEFNKDNM
FEKESTRIFDVDGNIYATLGSEKREKVSYDDLPQVLIDAIIATEDSRFFQHNGFDAPRFL
KASISQVLGRGGGGASTLTMQLSKLEYTDFEDQGIKGIIRKFTDIYMAVFKLEKAFTKEE
IIEYYVNIPCMGGNIYGVQQASQYYFGKDVGDINLVEAAMIAGMFQSPNGYNAYINPNDA
NARKNTVLYLMKRHGYISDDEYKAGTSVEIKDFLDEGVSSTNEYIGFIDTVVADVIEKTG
HNPYDIPMDIYTTMRKDKQDVINNFYKTYKFKDAKIQVGVAVVDVKTGALIAVGAGRNKK
GANTLNLATFDYQTKRHPGSTIKPILDYGPAIEYENLSTYGPFIDEKTPYGSGYMRNFNG
KYNGFMTMRDCLKNSVNTCALQAFNMTTNEQKMEFMTNLGVQPEEGITKLPLSYSVGAFN
TATPEILAGAYAAFGNGGYYTKPYSFTKIVYRESEEEYTPDIERKRVMKAQTAYILSTVL
TGVTTSRLKVSGTQVATKTGTSSYDTALLKSYGLGSSVIPDSWTSSYTTDYAMAIWYGYP
DGLTKDNVKNKYYMKMSHASNERLKIQAALGNKIYEKNAKFKNPGGLTTTEVELETIPAQ
KPSAYTPSKLKKSFIFISGTEPSEVSNRFSKLTDPTPGTYTLNGKSLTVTWNSPGIPEAA
DENYLLDYFNKGYTIWAEDYYKKRLSYNSSNIGDFGFAIYLTSGTSSTYVGFTKDTTYNI
DLSKYYGTFDGVIIKSIYSKFKSNASDGIKIAFNASGNEEKTYDVTMSNLTKTLNLNDKY
SYLDSSSVTSIKLNGNEIKSEVTDLNVSFTSISSKDGKSAQIDSFTSTAGTYKVTYTVTF
KHASNSTTKTFIQTVTVK

Enzyme Prediction     

No EC number prediction in MGYG000000430_01088.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT51	72	252	7.1e-52	0.9943502824858758

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG0744	MrcB	8.47e-125	13	605	2	577	Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
COG5009	MrcA	3.05e-73	21	706	3	788	Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].
pfam00912	Transgly	6.10e-65	72	252	1	177	Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
COG4953	PbpC	5.18e-62	65	602	36	538	Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis].
PRK14850	PRK14850	7.30e-41	55	563	119	645	penicillin-binding protein 1b; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QFF98737.1	5.96e-135	1	712	4	717
AWI12666.1	7.14e-133	9	725	18	727
ALC85822.1	1.76e-132	5	710	12	711
QUG41452.1	7.31e-126	27	710	33	711
AYA76804.1	1.83e-123	30	715	41	727

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3DWK_A	4.77e-76	67	599	9	557	ChainA, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_B Chain B, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_C Chain C, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_D Chain D, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL]
2OLU_A	1.98e-72	52	599	3	566	StructuralInsight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Apoenzyme [Staphylococcus aureus],2OLV_A Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex [Staphylococcus aureus],2OLV_B Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex [Staphylococcus aureus]
3ZG8_B	1.57e-42	171	641	2	469	CrystalStructure of Penicillin Binding Protein 4 from Listeria monocytogenes in the Ampicillin bound form [Listeria monocytogenes],3ZG9_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Cefuroxime bound form [Listeria monocytogenes],3ZGA_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Carbenicillin bound form [Listeria monocytogenes]
3ZG7_B	2.00e-39	171	641	2	469	CrystalStructure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the apo form [Listeria monocytogenes]
3UDF_A	1.91e-37	67	518	22	565	ChainA, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDF_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P39793	4.13e-101	5	715	11	731	Penicillin-binding protein 1A/1B OS=Bacillus subtilis (strain 168) OX=224308 GN=ponA PE=1 SV=1
Q04707	3.94e-84	31	604	18	604	Penicillin-binding protein 1A OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=ponA PE=1 SV=2
Q00573	4.30e-83	27	604	15	605	Penicillin-binding protein 1A (Fragment) OS=Streptococcus oralis OX=1303 GN=ponA PE=3 SV=1
Q8DR59	7.35e-83	31	604	18	604	Penicillin-binding protein 1A OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) OX=171101 GN=pbpA PE=1 SV=1
P38050	7.01e-62	30	624	13	589	Penicillin-binding protein 1F OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpF PE=2 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000027	0.000027	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

start	end
22	44