logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000000437_00485

You are here: Home > Sequence: MGYG000000437_00485

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Alistipes sp001941065
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes; Alistipes sp001941065
CAZyme ID MGYG000000437_00485
CAZy Family GH33
CAZyme Description Sialidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
384 MGYG000000437_9|CGC1 42587.5 7.0421
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000437 3341375 MAG Sweden Europe
Gene Location Start: 21046;  End: 22200  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000437_00485.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH33 38 378 1.7e-90 0.9678362573099415

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd15482 Sialidase_non-viral 3.92e-100 38 381 1 339
Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.
pfam13088 BNR_2 3.72e-33 62 361 1 280
BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.
COG4409 NanH 2.08e-08 60 364 376 700
Neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis].
cd00260 Sialidase 6.94e-05 51 183 15 143
sialidases/neuraminidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed beta-propeller fold. This hierarchy includes eubacterial, eukaryotic, and viral sialidases.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
BBD46002.1 4.76e-107 37 377 36 367
QDV16491.1 3.02e-102 39 383 40 379
QDT26944.1 6.05e-102 39 383 40 379
QDU50208.1 6.05e-102 39 383 40 379
QDT20890.1 1.71e-101 39 383 40 379

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4FJ6_A 6.82e-37 44 376 174 516
Crystalstructure of a glycoside hydrolase family 33, candidate sialidase (BDI_2946) from Parabacteroides distasonis ATCC 8503 at 1.90 A resolution [Parabacteroides distasonis ATCC 8503],4FJ6_B Crystal structure of a glycoside hydrolase family 33, candidate sialidase (BDI_2946) from Parabacteroides distasonis ATCC 8503 at 1.90 A resolution [Parabacteroides distasonis ATCC 8503],4FJ6_C Crystal structure of a glycoside hydrolase family 33, candidate sialidase (BDI_2946) from Parabacteroides distasonis ATCC 8503 at 1.90 A resolution [Parabacteroides distasonis ATCC 8503],4FJ6_D Crystal structure of a glycoside hydrolase family 33, candidate sialidase (BDI_2946) from Parabacteroides distasonis ATCC 8503 at 1.90 A resolution [Parabacteroides distasonis ATCC 8503]
6MNJ_A 3.24e-36 44 368 193 525
Hadzamicrobial sialidase Hz136 [Alistipes],6MNJ_B Hadza microbial sialidase Hz136 [Alistipes]
6MYV_A 6.61e-36 44 383 174 518
Sialidase26co-crystallized with DANA-Gc [bacterium],6MYV_B Sialidase26 co-crystallized with DANA-Gc [bacterium],6MYV_C Sialidase26 co-crystallized with DANA-Gc [bacterium],6MYV_D Sialidase26 co-crystallized with DANA-Gc [bacterium]
6MRV_A 8.74e-36 44 383 195 539
Sialidase26co-crystallized with DANA [bacterium],6MRV_B Sialidase26 co-crystallized with DANA [bacterium],6MRX_A Sialidase26 apo [bacterium],6MRX_B Sialidase26 apo [bacterium],6MRX_C Sialidase26 apo [bacterium],6MRX_D Sialidase26 apo [bacterium]
4Q6K_A 1.57e-34 44 375 177 518
Crystalstructure of a putative neuraminidase (BACCAC_01090) from Bacteroides caccae ATCC 43185 at 1.90 A resolution (PSI Community Target) [Bacteroides caccae ATCC 43185],4Q6K_B Crystal structure of a putative neuraminidase (BACCAC_01090) from Bacteroides caccae ATCC 43185 at 1.90 A resolution (PSI Community Target) [Bacteroides caccae ATCC 43185],4Q6K_C Crystal structure of a putative neuraminidase (BACCAC_01090) from Bacteroides caccae ATCC 43185 at 1.90 A resolution (PSI Community Target) [Bacteroides caccae ATCC 43185],4Q6K_D Crystal structure of a putative neuraminidase (BACCAC_01090) from Bacteroides caccae ATCC 43185 at 1.90 A resolution (PSI Community Target) [Bacteroides caccae ATCC 43185]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
A6BMK7 1.30e-31 51 366 77 396
Sialidase-1 OS=Bos taurus OX=9913 GN=NEU1 PE=2 SV=2
A5PF10 1.32e-31 51 366 78 397
Sialidase-1 OS=Sus scrofa OX=9823 GN=NEU1 PE=3 SV=1
O35657 3.13e-31 51 366 71 390
Sialidase-1 OS=Mus musculus OX=10090 GN=Neu1 PE=1 SV=1
Q99519 4.71e-31 51 366 77 396
Sialidase-1 OS=Homo sapiens OX=9606 GN=NEU1 PE=1 SV=1
Q5RAF4 4.71e-31 51 366 77 396
Sialidase-1 OS=Pongo abelii OX=9601 GN=NEU1 PE=2 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.873199 0.126323 0.000150 0.000154 0.000088 0.000105

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000437_00485.