CAZyme Information: MGYG000000442_02603

Basic Information

• Species: CAG-462 sp003489705
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; CAG-462; CAG-462 sp003489705
• CAZyme ID: MGYG000000442_02603
• CAZy Family: GT2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
815	MGYG000000442_53|CGC1	92073.72	5.6102

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000442	3125088	MAG	Sweden	Europe

• Gene Location: Start: 2283; End: 4730 Strand: +

Full Sequence      

MKPTICCFFPYTDDTSAAGILKELQDGTLPFQLHLLVRQQPSGAAPENYDYLVTDSPVST
SGLKAIVQASDEAEYLLLGIKPTSLQLGFHAVERMVQVARATEAGLVYADHYDLHADGSR
TLHPLIDYQRGSLRDDFDFGSLWLVRGGDLRLCLNDMPDYQAAALYHYRLWLAGQGARRI
IHLNECLYTEEETDTRLSGERQFDYVNPRNRDVQIEMERVCTEHLKAIGAYLYPDDFTDI
DLDTVPFDTEASVIIPVRNRVRTIGDAIRSALAQETSFPYNVIVIDNHSTDGTSEVIARL
ADTDKRVIHIRPERDDLGIGGCWNTGILHPACGRFAVQLDSDDLYSSTSTLQTMVDAFRS
QQCAMVVGTYRMTDFDLHTLPPGIIDHKEWTPDNGRNNALRINGLGAPRAFYTPLLRELL
LPNTSYGEDYAIGLALSRRYRIGRVYDVVYLCRRWEGNSDAALDIARVNTNNLYKDRLRT
LELEARIRHNRETWEYTPDGLEASAYLHRQLACWQETAQRYEALAHVEHRAFDNGLILQY
NPARIRSTGAKMDHATIATRPCFLCSAHRPKEQAHRPCFGTYELLVNPYPILPEHFTLAH
REHCPQRIEGHLADMLDMARSLTGYFIFYNGPRSGASAPDHLHFQAGSLGYVPLEIHLDR
WLSPRPSHTLYNNALTLHRLEDYFCPSLVAFLADCEAADRTRAVEACASWLRLLPRHDGD
DEPGMNLLAWHETDRERTVLVVIPRGKHRPACYGDGTDGTRTVSPGALDMGGLVITPRKE
DFTGLTPDETASILREVGLSDEEMQTWVERIQTGL

Enzyme Prediction     

No EC number prediction in MGYG000000442_02603.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	252	382	1e-21	0.7470588235294118

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam16269	DUF4922	5.88e-72	611	805	1	188	Domain of unknown function (DUF4922). This family consists of uncharacterized proteins around 310 residues in length and is mainly found in various Bacteroides and Parabacteroides species. Several members are annotated as putative glycosyltransferases, but the specific function of this family is still unknown.
cd00761	Glyco_tranf_GTA_type	1.80e-21	253	372	1	117	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.
COG0463	WcaA	2.40e-20	252	458	6	201	Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].
pfam00535	Glycos_transf_2	1.59e-18	252	420	1	164	Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.
cd06433	GT_2_WfgS_like	2.90e-17	252	372	1	115	WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUB69156.1	5.52e-261	2	812	4	798
QUB65927.1	7.80e-261	2	812	4	798
QUB78349.1	2.54e-259	2	812	4	799
VEH16693.1	3.06e-259	5	812	5	803
QUB73035.1	6.95e-259	2	812	4	798

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q92IF9	5.81e-08	248	345	292	384	Uncharacterized glycosyltransferase RC0461 OS=Rickettsia conorii (strain ATCC VR-613 / Malish 7) OX=272944 GN=RC0461 PE=3 SV=1
Q4UM29	1.74e-07	248	345	292	384	Uncharacterized glycosyltransferase RF_0543 OS=Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) OX=315456 GN=RF_0543 PE=3 SV=1
Q1RIM7	8.72e-06	248	445	290	480	Uncharacterized glycosyltransferase RBE_0706 OS=Rickettsia bellii (strain RML369-C) OX=336407 GN=RBE_0706 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000077	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000442_02603.