CAZyme Information: MGYG000000450_01224

Basic Information

• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; UMGS1826
• CAZyme ID: MGYG000000450_01224
• CAZy Family: GT2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
418		46581.61	9.6345

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000450	2671977	MAG	Sweden	Europe

• Gene Location: Start: 14870; End: 16126 Strand: -

Full Sequence      

MKTLLSLCASLAWGINCVLIFYAVYNVTVALPALKRRRTPRTFAPQKRFAILVAARNEES
VIGGLVESLLAQDYPRGLFDVYVLPNNCSDDTAGAARRAGARILDCPGPIRCKGDALSYA
FDLLLETGCYDAFCVFDADNLADKGFLRAMNSALCGGAQAAQGRRDSKNPYDSPISGSYA
VYYWMLSRFYNQPRSVWGLSAVINGCGFMVSAELLRKMGGFHTQTMTEDLEFTTQCILQD
VRVRWVPEAVLYDESPLTFAPSWKQRRRWSTGLLQCGKLYGPRLLGKALRERSLTALDQF
IFLLAPVMQVLSILPAALAMTLVLLTPNWTASTLLPWALRSLLRPALFFGAVTLLGAFFT
TLLERRPLARMAKAIGYYGLFLLTWIPINLLCFVKKSTVWAEIKHTRQIRLAELPNAK

Enzyme Prediction     

No EC number prediction in MGYG000000450_01224.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	46	271	1.6e-26	0.9869565217391304

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd06438	EpsO_like	3.65e-55	51	232	1	183	EpsO protein participates in the methanolan synthesis. The Methylobacillus sp EpsO protein is predicted to participate in the methanolan synthesis. Methanolan is an exopolysaccharide (EPS), composed of glucose, mannose and galactose. A 21 genes cluster was predicted to participate in the methanolan synthesis. Gene disruption analysis revealed that EpsO is one of the glycosyltransferase enzymes involved in the synthesis of repeating sugar units onto the lipid carrier.
COG1215	BcsA	3.99e-41	1	399	12	417	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility].
cd06423	CESA_like	6.90e-35	51	229	1	180	CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.
pfam13641	Glyco_tranf_2_3	6.89e-23	48	272	3	230	Glycosyltransferase like family 2. Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis.
cd06421	CESA_CelA_like	5.32e-19	48	275	2	232	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose. Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QOX65217.1	7.24e-112	2	414	6	421
ADO38773.1	3.19e-107	22	414	19	410
ARD65366.1	3.19e-107	22	414	19	410
ALU13522.1	9.02e-107	22	414	19	410
QCT71577.1	9.02e-107	22	414	19	410

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P74165	1.32e-14	45	272	106	335	Beta-monoglucosyldiacylglycerol synthase OS=Synechocystis sp. (strain PCC 6803 / Kazusa) OX=1111708 GN=sll1377 PE=1 SV=1
Q3MB01	3.02e-12	50	272	109	333	Beta-monoglucosyldiacylglycerol synthase OS=Trichormus variabilis (strain ATCC 29413 / PCC 7937) OX=240292 GN=Ava_2217 PE=1 SV=1
Q8YMK0	5.36e-12	50	272	109	333	Beta-monoglucosyldiacylglycerol synthase OS=Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) OX=103690 GN=all4933 PE=1 SV=1
Q9WX61	9.60e-06	60	302	163	409	Cellulose synthase 1 catalytic subunit [UDP-forming] OS=Komagataeibacter xylinus OX=28448 GN=bcsAI PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000036	0.000004	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

start	end
10	32
300	322
342	363
375	394