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CAZyme Information: MGYG000000470_02371

You are here: Home > Sequence: MGYG000000470_02371

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Brachyspira pilosicoli
Lineage Bacteria; Spirochaetota; Brachyspirae; Brachyspirales; Brachyspiraceae; Brachyspira; Brachyspira pilosicoli
CAZyme ID MGYG000000470_02371
CAZy Family GT9
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
326 37158.2 9.1047
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000470 2694868 MAG Fiji Oceania
Gene Location Start: 1526;  End: 2506  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000470_02371.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT9 66 296 1.9e-36 0.9333333333333333

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG0859 RfaF 1.25e-45 1 266 2 282
ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis].
cd03789 GT9_LPS_heptosyltransferase 8.61e-44 2 311 1 267
lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
PRK10422 PRK10422 1.19e-16 2 264 7 291
lipopolysaccharide core biosynthesis protein; Provisional
pfam01075 Glyco_transf_9 7.85e-15 66 279 8 227
Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ADK30478.1 5.72e-238 1 326 1 326
AGA65489.1 1.15e-237 1 326 1 326
AFR70259.1 1.64e-237 1 326 1 326
CCG57234.1 4.70e-237 1 326 1 326
AEM21447.1 2.27e-169 2 326 3 329

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P25742 1.05e-13 8 264 1 279
Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli (strain K12) OX=83333 GN=rfaQ PE=3 SV=2
Q9R9D5 1.33e-10 8 264 1 279
Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli OX=562 GN=rfaQ PE=1 SV=1
P37692 6.57e-07 1 266 1 292
ADP-heptose--LPS heptosyltransferase 2 OS=Escherichia coli (strain K12) OX=83333 GN=rfaF PE=1 SV=1
P37421 1.17e-06 1 266 1 292
ADP-heptose--LPS heptosyltransferase 2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfaF PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000044 0.000002 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000470_02371.