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CAZyme Information: MGYG000000546_01139
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Roseburia sp003483745 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia; Roseburia sp003483745 | |||||||||||
| CAZyme ID | MGYG000000546_01139 | |||||||||||
| CAZy Family | GH74 | |||||||||||
| CAZyme Description | Xyloglucanase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 10295; End: 12619 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH74 | 90 | 219 | 4.2e-19 | 0.5407725321888412 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam15902 | Sortilin-Vps10 | 2.60e-06 | 96 | 221 | 1 | 117 | Sortilin, neurotensin receptor 3,. Sortilin, also known in mammals as neurotensin receptor-3, is the archetypical member of a Vps10-domain (Vps10-D) that binds neurotrophic factors and neuropeptides. This domain constitutes the entire luminal part of Sortilin and is activated in the trans-Golgi network by enzymatic propeptide cleavage. The structure of the domain has been determined as a ten-bladed propeller, with up to 9 BNR or beta-hairpin turns in it. The mature receptor binds various ligands, including its own propeptide (Sort-pro), neurotensin, the pro-forms of nerve growth factor-beta (NGF)6 and brain-derived neurotrophic factor (BDNF)7, lipoprotein lipase (LpL), apo lipoprotein AV14 and the receptor-associated protein (RAP)1. |
| smart00602 | VPS10 | 0.004 | 96 | 250 | 55 | 203 | VPS10 domain. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| CBL08979.1 | 0.0 | 1 | 774 | 1 | 774 |
| CBL11475.1 | 0.0 | 1 | 774 | 1 | 774 |
| VCV22800.1 | 0.0 | 1 | 774 | 1 | 774 |
| ADZ84378.1 | 1.76e-313 | 1 | 771 | 1 | 770 |
| QEH69849.1 | 3.53e-313 | 1 | 771 | 1 | 770 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6P2M_A | 1.77e-65 | 9 | 770 | 10 | 691 | ChainA, Type 3a cellulose-binding domain protein [Caldicellulosiruptor lactoaceticus 6A] |
| 2CN3_A | 1.68e-55 | 2 | 771 | 4 | 730 | ChainA, BETA-1,4-XYLOGLUCAN HYDROLASE [Acetivibrio thermocellus],2CN3_B Chain B, BETA-1,4-XYLOGLUCAN HYDROLASE [Acetivibrio thermocellus] |
| 2CN2_A | 2.35e-53 | 2 | 771 | 4 | 730 | ChainA, BETA-1,4-XYLOGLUCAN HYDROLASE [Acetivibrio thermocellus],2CN2_B Chain B, BETA-1,4-XYLOGLUCAN HYDROLASE [Acetivibrio thermocellus],2CN2_C Chain C, BETA-1,4-XYLOGLUCAN HYDROLASE [Acetivibrio thermocellus],2CN2_D Chain D, BETA-1,4-XYLOGLUCAN HYDROLASE [Acetivibrio thermocellus] |
| 6MGL_A | 1.66e-52 | 18 | 771 | 16 | 745 | Crystalstructure of the catalytic domain from GH74 enzyme PoGH74 from Paenibacillus odorifer, D60A mutant in complex with XXLG and XGXXLG xyloglucan [Paenibacillus odorifer] |
| 7KN8_A | 2.87e-52 | 9 | 771 | 10 | 713 | ChainA, Cellulase [Xanthomonas campestris pv. campestris str. ATCC 33913],7KN8_B Chain B, Cellulase [Xanthomonas campestris pv. campestris str. ATCC 33913] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q3MUH7 | 2.29e-59 | 9 | 771 | 38 | 765 | Xyloglucanase OS=Paenibacillus sp. OX=58172 GN=xeg74 PE=1 SV=1 |
| Q70DK5 | 2.47e-55 | 2 | 771 | 31 | 757 | Xyloglucanase Xgh74A OS=Acetivibrio thermocellus OX=1515 GN=xghA PE=1 SV=1 |
| A3DFA0 | 4.54e-55 | 2 | 771 | 31 | 757 | Xyloglucanase Xgh74A OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=xghA PE=3 SV=1 |
| A1DAU0 | 5.27e-52 | 9 | 772 | 27 | 798 | Probable oligoxyloglucan-reducing end-specific xyloglucanase OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=xgcA PE=3 SV=1 |
| Q5BD38 | 1.25e-51 | 1 | 773 | 25 | 809 | Oligoxyloglucan-reducing end-specific xyloglucanase OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=xgcA PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000072 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |