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CAZyme Information: MGYG000000550_00173

You are here: Home > Sequence: MGYG000000550_00173

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Lawsonibacter sp900545895
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Oscillospiraceae; Lawsonibacter; Lawsonibacter sp900545895
CAZyme ID MGYG000000550_00173
CAZy Family GH18
CAZyme Description Spore germination protein YaaH
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
141 16202.32 4.9059
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000550 2679456 MAG China Asia
Gene Location Start: 2891;  End: 3316  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000550_00173.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH18 3 116 7.9e-21 0.36824324324324326

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd02874 GH18_CFLE_spore_hydrolase 9.70e-60 1 127 187 313
Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis.
COG3858 YaaH 1.86e-46 1 128 291 419
Spore germination protein YaaH [Cell cycle control, cell division, chromosome partitioning].
smart00636 Glyco_18 1.62e-15 5 116 208 331
Glyco_18 domain.
cd02875 GH18_chitobiase 2.35e-14 1 115 201 335
Chitobiase (also known as di-N-acetylchitobiase) is a lysosomal glycosidase that hydrolyzes the reducing-end N-acetylglucosamine from the chitobiose core of oligosaccharides during the ordered degradation of asparagine-linked glycoproteins in eukaryotes. Chitobiase can only do so if the asparagine that joins the oligosaccharide to protein is previously removed by a glycosylasparaginase. Chitobiase is therefore the final step in the lysosomal degradation of the protein/carbohydrate linkage component of asparagine-linked glycoproteins. The catalytic domain of chitobiase is an eight-stranded alpha/beta barrel fold similar to that of other family 18 glycosyl hydrolases such as hevamine and chitotriosidase.
cd06549 GH18_trifunctional 1.99e-13 1 116 179 290
GH18 domain of an uncharacterized family of bacterial proteins, which share a common three-domain architecture: an N-terminal glycosyl hydrolase family 18 (GH18) domain, a glycosyl transferase family 2 domain, and a C-terminal polysaccharide deacetylase domain.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QIA30964.1 2.75e-63 1 133 29 162
ALP93864.1 2.10e-60 1 133 290 423
QQR05785.1 4.77e-60 1 133 290 423
ANU41359.1 4.77e-60 1 133 290 423
QBB66106.1 2.33e-59 1 133 290 423

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4S3K_A 1.37e-42 1 133 296 429
ChainA, Spore germination protein YaaH [Priestia megaterium QM B1551]
4S3J_A 5.59e-40 1 138 294 432
Crystalstructure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_B Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_C Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876]
3CZ8_A 1.87e-31 3 116 195 308
ChainA, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168],3CZ8_B Chain B, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168]
5JH8_A 2.36e-14 13 125 200 308
Crystalstructure of chitinase from Chromobacterium violaceum ATCC 12472 [Chromobacterium violaceum ATCC 12472]
4Q6T_A 3.15e-12 10 129 214 337
Thecrystal structure of a class V chitininase from Pseudomonas fluorescens Pf-5 [Pseudomonas protegens Pf-5]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P37531 9.10e-43 2 133 293 425
Cortical fragment-lytic enzyme OS=Bacillus subtilis (strain 168) OX=224308 GN=sleL PE=1 SV=2
Q9K3E4 1.12e-38 1 133 293 426
Cortical fragment-lytic enzyme OS=Bacillus cereus OX=1396 GN=sleL PE=1 SV=1
P0DPJ9 3.06e-38 1 133 293 426
Cortical fragment-lytic enzyme OS=Bacillus anthracis OX=1392 GN=sleL PE=2 SV=1
O05495 3.27e-32 3 133 287 417
Putative sporulation-specific glycosylase YdhD OS=Bacillus subtilis (strain 168) OX=224308 GN=ydhD PE=1 SV=2
Q01460 2.00e-12 14 115 221 340
Di-N-acetylchitobiase OS=Rattus norvegicus OX=10116 GN=Ctbs PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000034 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000550_00173.