CAZyme Information: MGYG000000559_02067

Basic Information

• Species: Paraprevotella sp900546665
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Paraprevotella; Paraprevotella sp900546665
• CAZyme ID: MGYG000000559_02067
• CAZy Family: GH98
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1050		118578.59	4.5033

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000559	3371833	MAG	China	Asia

• Gene Location: Start: 977; End: 4129 Strand: -

Full Sequence      

MKNVSLFQKLLLSLLLITSALTMDAQQRRPIDSKHPMWLVHIDVWNSADPQKIIDLIPDD
IKPYVCLNLSLSCSYDVAKGVHTRPQNAVLTYKSWASVCQANNMWFTCQPASGGHTHILD
DDLETFEYFFKHYPNFLGWNFAEQFWGFDAPGDKYSSKMDERIALFAQLVEMSHRYGGLL
TISYCGSLSHDLNPLGMMKGNNDLLEACKKYPEAILWLFKYTTCSWWYNNESVVLGPFVS
GLANNYGVRYDECGWSSSMSIIYGENNDRTYPTSWGIGTVMEQTGVNGGAVWDGPELIWT
ADFKEVNTTTTSDGYTRRNWETYPGFDNAWVDMFRKIIDGTLYIPTREEVVNETKVIVVN
DVTSGSNEDQYGSIRTLYDGLYKQDDPLNFNDGYGDDNQCFFKKTGRYRTIPVTIAFNDE
AAEQIPMVVKKSEYSTLWPTEEAKVEEFNKLYPEVSTGDLYVSRFKNQLITYTPYTYLNA
KTTAKGVIPLQYNTCDRMELTWGKLSSGVVREYADHIDFYLNNYRTDTTTLVTDRIVICG
ATSEPTYNMTLRGEAEGHSTASWDPESQQFTLDVTHLGPVDLTVNCAGEATDRRTDEVSN
QPLTADLPKQPDEYKGTIIIEAEDMDYKDVLRCSTYPYGEYPDVRGHSGNGFVDMGTGNN
ASLKHDLDMTVSGRYTVSVRYTSDKSNGILYATMTNENGRTSKTLNTERTLTNEWKKIDF
EVDLTEGVNTLIIKKRSQASMYIDNVTYTPEGTPVEQFNITVLDAEHGKASVTTTQATEG
ELITIQVEPDPGYVLRKWDVNRNNVIVRDDNTFVMPDDNVKITPVFAVDLEDYVYYLDYT
DVNGGGMPQGWRAEDGQGGEMHEYPNGYGSGPRIFEELSACQGKALYWRNSFADYGSQPN
FLLKLSPGSYALSFTMAAWKGEPTYKAQILNKRSGKIVAESPVYVAEPNANGNTGFEFGD
IQTHKMEFDIEEEDNYVIRFQTVSGGWSEYLLFGCNIEDLSDPSGITVVKPVENQIDRIY
SPAGILLKNVQKGINIIRYTDGTVRKVLVK

Enzyme Prediction     

EC	3.2.1.8

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH98	25	342	1.1e-83	0.9908256880733946

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam08306	Glyco_hydro_98M	3.00e-86	25	342	5	328	Glycosyl hydrolase family 98. This domain is the putative catalytic domain of glycosyl hydrolase family 98 proteins.
pfam08307	Glyco_hydro_98C	1.49e-12	347	585	1	268	Glycosyl hydrolase family 98 C-terminal domain. This putative domain is found at the C-terminus of glycosyl hydrolase family 98 proteins. This domain is not expected to form part of the catalytic activity.
cd04083	CBM35_Lmo2446-like	4.87e-10	646	748	22	125	Carbohydrate Binding Module 35 (CBM35) domains similar to Lmo2446. This family includes carbohydrate binding module 35 (CBM35) domains that are appended to several carbohydrate binding enzymes. Some CBM35 domains belonging to this family are appended to glycoside hydrolase (GH) family domains, including glycoside hydrolase family 31 (GH31), for example the CBM35 domain of Lmo2446, an uncharacterized protein from Listeria monocytogenes EGD-e. These CBM35s are non-catalytic carbohydrate binding domains that facilitate the strong binding of the GH catalytic modules with their dedicated, insoluble substrates. GH31 has a wide range of hydrolytic activities such as alpha-glucosidase, alpha-xylosidase, 6-alpha-glucosyltransferase, or alpha-1,4-glucan lyase, cleaving a terminal carbohydrate moiety from a substrate that may be a starch or a glycoprotein. Most characterized GH31 enzymes are alpha-glucosidases.
pfam18998	Flg_new_2	1.35e-05	758	827	1	71	Divergent InlB B-repeat domain. This family of domains are found in bacterial cell surface proteins. They are often found in tandem array. This domain is closely related to pfam09479.
cd04086	CBM35_mannanase-like	0.002	646	747	21	117	Carbohydrate Binding Module 35 (CBM35); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains. This family includes carbohydrate binding module 35 (CBM35) domains that are appended to several carbohydrate binding enzymes, including periplasmic component of ABC-type sugar transport system involved in carbohydrate transport and metabolism, and several glycoside hydrolase (GH) domains, including GH26. These CBM6s are non-catalytic carbohydrate binding domains that facilitate the strong binding of the GH catalytic modules with their dedicated, insoluble substrates. Examples of proteins having CMB35s belonging to this family are mannanase A from Clostridium thermocellum (GH26), Man26B from Paenibacillus sp. BME-14 (GH26), and the multifunctional Cel44C-Man26A from Paenibacillus polymyxa GS01 (which has two GH domains, GH44 and GH26). GH26 mainly includes mannan endo-1,4-beta-mannosidase which hydrolyzes 1,4-beta-D-linkages in mannans, galacto-mannans, glucomannans, and galactoglucomannans, but displays little activity towards other plant cell wall polysaccharides. A few proteins belonging to this family have additional CBM3 domains; these CBM3s are not found in the CBM6-CBM35-CBM36_like superfamily.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AGB29515.1	0.0	6	1049	1	1034
AXY74108.1	8.23e-177	11	750	16	750
AOZ99817.1	2.40e-176	24	845	29	831
QUT78600.1	1.28e-173	28	746	228	934
QUT26887.1	1.28e-173	28	746	228	934

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2WMH_A	2.71e-18	26	584	28	581	Crystalstructure of the catalytic module of a family 98 glycoside hydrolase from Streptococcus pneumoniae TIGR4 in complex with the H- disaccharide blood group antigen. [Streptococcus pneumoniae TIGR4]
2WMF_A	6.25e-18	26	584	28	581	Crystalstructure of the catalytic module of a family 98 glycoside hydrolase from Streptococcus pneumoniae TIGR4 (Sp4GH98) in its native form. [Streptococcus pneumoniae TIGR4]
2WMG_A	1.90e-17	206	584	198	581	Crystalstructure of the catalytic module of a family 98 glycoside hydrolase from Streptococcus pneumoniae TIGR4 (Sp4GH98) in complex with the LewisY pentasaccharide blood group antigen. [Streptococcus pneumoniae TIGR4]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.003098	0.995643	0.000434	0.000320	0.000237	0.000214

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000559_02067.