CAZyme Information: MGYG000000574_00103

Basic Information

• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae
• CAZyme ID: MGYG000000574_00103
• CAZy Family: GH33
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
981	MGYG000000574_6|CGC1	110458.92	4.5268

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000574	5306470	MAG	Madagascar	Africa

• Gene Location: Start: 13551; End: 16496 Strand: -

Full Sequence      

MKKKEKKIISFLLAVVCIASSASIQASATDLNTDISWFGSQNGNPWNGSKWTFCHGRDGD
FTKMPYYVTESKCWSSNEDGSKTKIDTWRHYATPEDWAVTAFSINEDGNISGDSRQPVKL
EGTTNNAADLMVVLKSKENERFYPVYPVAGAWEWRTVSPGEVAEFSFETGYKAGDVLYYI
VKAPDNEEITRLQICPQVVFRGGTPATYPETFTEFPSDQERPQDVALIPAEIHRNLSEEK
YQDANRQYQGCPAIEVTEGGRLWAGFMTGGVDEGAENYNMLVYSDDKGQTWSSPQFAIEA
GEEVRVSEPVLWRASDGRLWVLWAQAYHWYDGRQGVFLSICDNPDAEPGQMSWSKPVRIA
NGYINTKPTERSDGSVVLNLPLWEAFDSDYNYLPEERYSNVYVTRDNGESFQFLGKADVP
NRTFDEPMIIEKKDGSLWMLVRTDYGIGESFSYDGGKTWTKGVPSEIAGPSSRFYIGRLQ
SGNLLLVNHYNFNGRSHMTAMISEDDGTTWKGFLLLDERINVSYPDVTQDQDGRIYVVYD
HERYADKEILMASFTEEEVRNGSLSDTAVVKKLINQAMGETPLKEEISFLHSWQFNASDK
TQPVSIKTNGVHGYSYEYGTNGIFEGLNTYDTNLAAWTDDGANPMIASWYMGAAWDKDCA
LIWHTPGSGKAVITTGFALEQKEKGGKIAQFMVAQRRNGQYYPLYPEKGSFVWQEIGPDD
VVSMPEITTRIEKNDEVVFVLRGDNVQLKFNPNVVLYQSLGTSEPVVGFQDWPKETEQKD
PVVKEYTKAEYEEFKSADETPKLEGYVFTGWFTSAEVDTEENMKAHVLRNVAGLTDSDLV
YARFVGESMLDVKAQLNADADSSSEEAHMRLLTTADNLAYRKIGFKITINGKTRDTANNI
VYRQLDDTIINGVKETITPDCFHKNSQYFKAYTIKNIPQNSFDTSIEVTPYLVTLDGTTV
YGRTVSKTVNQGIAARESNVQ

Enzyme Prediction     

No EC number prediction in MGYG000000574_00103.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH33	397	548	5.8e-21	0.45614035087719296

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd15482	Sialidase_non-viral	7.61e-44	252	555	17	339	Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.
pfam13088	BNR_2	1.77e-27	260	537	1	280	BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.
pfam15902	Sortilin-Vps10	2.32e-07	399	574	1	178	Sortilin, neurotensin receptor 3,. Sortilin, also known in mammals as neurotensin receptor-3, is the archetypical member of a Vps10-domain (Vps10-D) that binds neurotrophic factors and neuropeptides. This domain constitutes the entire luminal part of Sortilin and is activated in the trans-Golgi network by enzymatic propeptide cleavage. The structure of the domain has been determined as a ten-bladed propeller, with up to 9 BNR or beta-hairpin turns in it. The mature receptor binds various ligands, including its own propeptide (Sort-pro), neurotensin, the pro-forms of nerve growth factor-beta (NGF)6 and brain-derived neurotrophic factor (BDNF)7, lipoprotein lipase (LpL), apo lipoprotein AV14 and the receptor-associated protein (RAP)1.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QDU03573.1	3.74e-111	216	585	28	398
QDT21480.1	7.35e-111	212	585	24	398
QDT85478.1	1.09e-109	216	585	28	398
QDU50763.1	2.38e-107	217	585	26	398
QDT79764.1	3.96e-107	217	579	27	390

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000277	0.998985	0.000180	0.000198	0.000173	0.000155

TMHMM  Annotations     

start	end
7	29