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CAZyme Information: MGYG000000575_03883
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | UBA11452 sp003526375 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Verrucomicrobiota; Lentisphaeria; Victivallales; UBA1829; UBA11452; UBA11452 sp003526375 | |||||||||||
| CAZyme ID | MGYG000000575_03883 | |||||||||||
| CAZy Family | GH29 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 816; End: 2552 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH29 | 3 | 329 | 4.1e-91 | 0.8815028901734104 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam01120 | Alpha_L_fucos | 1.83e-91 | 8 | 320 | 22 | 327 | Alpha-L-fucosidase. |
| smart00812 | Alpha_L_fucos | 1.01e-86 | 4 | 339 | 19 | 348 | Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. |
| COG3669 | AfuC | 2.88e-36 | 18 | 333 | 1 | 324 | Alpha-L-fucosidase [Carbohydrate transport and metabolism]. |
| pfam14871 | GHL6 | 1.84e-05 | 65 | 193 | 1 | 127 | Hypothetical glycosyl hydrolase 6. GHL6 is a family of hypothetical glycoside hydrolases. |
| cd04079 | CBM6_agarase-like | 0.006 | 464 | 496 | 33 | 65 | Carbohydrate Binding Module 6 (CBM6); appended mainly to glycoside hydrolase (GH) family 16 alpha- and beta agarases. This family includes carbohydrate binding module 6 (CBM6) domains that are appended mainly to glycoside hydrolase (GH) family 16 agarases. These CBM6s are non-catalytic carbohydrate binding domains that facilitate the activity of alpha- and beta-agarase catalytic modules which are involved in the hydrolysis of 1,4-beta-D-galactosidic linkages. These CBM6s bind specifically to the non-reducing end of agarose chains, recognizing only the first repeat of the disaccharide, and directing the appended catalytic modules to areas of the plant cell wall attacked by beta-agarases. CBM6 is an unusual CBM as it represents a chimera of two distinct binding sites with different modes of binding: binding site I within the loop regions and binding site II on the concave face of the beta-sandwich fold. This family includes three tandem CBM6s from the Saccharophagus degradans agarase Aga86E, and three tandem CBM6s from Vibrio sp. strain PO-303 AgaA; in both these proteins these are appended to a GH16 domain. Vibrio AgaA also contains a Big-2-like protein-protein interaction domain. This family also includes two tandem CBM6s from an endo-type beta-agarase from a deep-sea Microbulbifer-like isolate, which are appended to a GH16 domain, and two of three CBM6s of Alteromonas agarilytica AgaA alpha-agarase, which are appended to a GH96 domain. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QYY35982.1 | 1.67e-176 | 2 | 558 | 7 | 562 |
| QGY47812.1 | 2.89e-112 | 2 | 555 | 26 | 566 |
| QGY42537.1 | 5.11e-106 | 5 | 527 | 30 | 538 |
| AQQ70371.1 | 6.86e-105 | 8 | 556 | 15 | 547 |
| QYM79712.1 | 4.39e-103 | 2 | 556 | 20 | 557 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6O18_A | 1.38e-91 | 1 | 304 | 1 | 322 | ChainA, AlfC [Lacticaseibacillus casei],6O18_B Chain B, AlfC [Lacticaseibacillus casei],6O18_C Chain C, AlfC [Lacticaseibacillus casei],6O18_D Chain D, AlfC [Lacticaseibacillus casei],6O1A_A Chain A, AlfC [Lacticaseibacillus casei],6O1A_B Chain B, AlfC [Lacticaseibacillus casei],6O1A_C Chain C, AlfC [Lacticaseibacillus casei],6O1A_D Chain D, AlfC [Lacticaseibacillus casei] |
| 6O1I_A | 1.08e-90 | 1 | 304 | 1 | 322 | ChainA, AlfC [Lacticaseibacillus casei],6O1I_B Chain B, AlfC [Lacticaseibacillus casei],6O1I_C Chain C, AlfC [Lacticaseibacillus casei],6O1I_D Chain D, AlfC [Lacticaseibacillus casei] |
| 6O1J_A | 2.15e-90 | 1 | 304 | 1 | 322 | ChainA, AlfC [Lacticaseibacillus casei],6O1J_B Chain B, AlfC [Lacticaseibacillus casei],6O1J_C Chain C, AlfC [Lacticaseibacillus casei],6O1J_D Chain D, AlfC [Lacticaseibacillus casei],6O1J_E Chain E, AlfC [Lacticaseibacillus casei],6O1J_F Chain F, AlfC [Lacticaseibacillus casei],6O1J_G Chain G, AlfC [Lacticaseibacillus casei],6O1J_H Chain H, AlfC [Lacticaseibacillus casei] |
| 6O1C_A | 2.15e-90 | 1 | 304 | 1 | 322 | ChainA, AlfC [Lacticaseibacillus casei],6O1C_B Chain B, AlfC [Lacticaseibacillus casei],6O1C_C Chain C, AlfC [Lacticaseibacillus casei],6O1C_D Chain D, AlfC [Lacticaseibacillus casei],6O1C_E Chain E, AlfC [Lacticaseibacillus casei],6O1C_F Chain F, AlfC [Lacticaseibacillus casei],6O1C_G Chain G, AlfC [Lacticaseibacillus casei],6O1C_H Chain H, AlfC [Lacticaseibacillus casei],6OHE_A Chain A, AlfC [Lacticaseibacillus casei],6OHE_B Chain B, AlfC [Lacticaseibacillus casei],6OHE_C Chain C, AlfC [Lacticaseibacillus casei],6OHE_D Chain D, AlfC [Lacticaseibacillus casei] |
| 7DB5_A | 8.90e-62 | 13 | 356 | 42 | 387 | ChainA, Alpha-L-fucosidase [Vibrio sp. EJY3] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q99LJ1 | 3.81e-28 | 8 | 359 | 39 | 378 | Tissue alpha-L-fucosidase OS=Mus musculus OX=10090 GN=Fuca1 PE=1 SV=1 |
| Q60HF8 | 1.13e-27 | 8 | 333 | 55 | 376 | Tissue alpha-L-fucosidase OS=Macaca fascicularis OX=9541 GN=FUCA1 PE=2 SV=1 |
| Q2KIM0 | 1.52e-27 | 8 | 348 | 56 | 392 | Tissue alpha-L-fucosidase OS=Bos taurus OX=9913 GN=FUCA1 PE=2 SV=1 |
| P04066 | 1.21e-26 | 8 | 333 | 53 | 374 | Tissue alpha-L-fucosidase OS=Homo sapiens OX=9606 GN=FUCA1 PE=1 SV=4 |
| P17164 | 2.85e-26 | 8 | 333 | 49 | 370 | Tissue alpha-L-fucosidase OS=Rattus norvegicus OX=10116 GN=Fuca1 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000039 | 0.000001 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |