CAZyme Information: MGYG000000576_00354

Basic Information

• Lineage: Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
• CAZyme ID: MGYG000000576_00354
• CAZy Family: GT5
• CAZyme Description: Glycogen synthase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
475	MGYG000000576_6|CGC2	53937.27	4.6263

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000576	1830013	MAG	Madagascar	Africa

• Gene Location: Start: 31241; End: 32668 Strand: +

Full Sequence      

MKIMFVAAEGAPFAKTGGLGDVIGALPKSLVKNGNEVAVVLPYYDVVDAKFGDQVEDVMY
FYTELGWRRVYVGVKKIIRDGVTFYFIDNHDYFFRGHVYGDWDDGERFAFFQLAALELME
KVDFIPDVLHVHDYHTGMIPFLLKEKYHWINAYKDIKTVFTIHNIEFQGQFDPGMLWELF
GVGYERYADGTLRWNDCLNWMKAAVLYADRVTTVSPSYAEEIKTPAFGKGLDQIMRMESG
KLSGIVNGIDTDLFNPETDPHLVTHFSVDDLTGKAKDKAALQERVGLPVRDDVPLIGIVS
RLTDQKGFDLVVNELSNILKRDLQIVVLGTGYADYENAFSWFGQHYPDKLSANITFDLEL
AQQIYAACDLFLMPSAFEPCGLSQMMAMRYGTLPLVHEVGGLRDTVESYNPVTGSGTGFS
FNNFSGFWMTTTLDFALDTYKNHKDAWRKLQEQAMTRDFSWDSASQDYIALYQDL

Enzyme Prediction     

No EC number prediction in MGYG000000576_00354.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT5	2	473	7.1e-180	0.9957627118644068

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG0297	GlgA	0.0	1	473	1	476	Glycogen synthase [Carbohydrate transport and metabolism].
TIGR02095	glgA	0.0	1	475	1	473	glycogen/starch synthase, ADP-glucose type. This family consists of glycogen (or starch) synthases that use ADP-glucose (EC 2.4.1.21), rather than UDP-glucose (EC 2.4.1.11) as in animals, as the glucose donor. This enzyme is found in bacteria and plants. Whether the name given is glycogen synthase or starch synthase depends on context, and therefore on substrate. [Energy metabolism, Biosynthesis and degradation of polysaccharides]
PRK00654	glgA	0.0	1	475	1	463	glycogen synthase GlgA.
cd03791	GT5_Glycogen_synthase_DULL1-like	0.0	2	474	1	474	Glycogen synthase GlgA and similar proteins. This family is most closely related to the GT5 family of glycosyltransferases. Glycogen synthase (EC:2.4.1.21) catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family includes starch synthases of plants, such as DULL1 in Zea mays and glycogen synthases of various organisms.
PRK14099	PRK14099	1.53e-129	1	475	4	479	glycogen synthase GlgA.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AXQ78356.1	7.60e-307	1	475	1	475
QGU78232.1	2.26e-306	1	475	1	475
QGU82253.1	2.26e-306	1	475	1	475
QKH70084.1	4.56e-306	1	475	1	475
AMB83144.1	4.56e-306	1	475	1	475

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4HLN_A	5.22e-103	2	473	126	623	Structureof barley starch synthase I in complex with maltooligosaccharide [Hordeum vulgare]
6GNE_A	2.73e-89	1	472	10	494	Catalyticdomain of Starch Synthase IV from Arabidopsis thaliana bound to ADP and acarbose [Arabidopsis thaliana],6GNE_B Catalytic domain of Starch Synthase IV from Arabidopsis thaliana bound to ADP and acarbose [Arabidopsis thaliana]
3D1J_A	9.39e-85	1	475	1	476	ChainA, Glycogen synthase [Escherichia coli]
2QZS_A	1.64e-84	1	475	1	476	CrystalStructure of Wild-type E.coli GS in complex with ADP and Glucose(wtGSb) [Escherichia coli],2R4T_A Crystal Structure of Wild-type E.coli GS in Complex with ADP and Glucose(wtGSc) [Escherichia coli],2R4U_A Crystal Structure of Wild-type E.coli GS in complex with ADP and Glucose(wtGSd) [Escherichia coli],3GUH_A Crystal Structure of Wild-type E.coli GS in complex with ADP and DGM [Escherichia coli K-12]
3COP_A	1.28e-83	1	475	1	476	ChainA, Glycogen synthase [Escherichia coli],3CX4_A Chain A, Glycogen synthase [Escherichia coli]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q8CWX0	1.27e-290	1	475	1	475	Glycogen synthase OS=Streptococcus mutans serotype c (strain ATCC 700610 / UA159) OX=210007 GN=glgA PE=3 SV=1
B9DRS8	3.25e-282	1	475	1	475	Glycogen synthase OS=Streptococcus uberis (strain ATCC BAA-854 / 0140J) OX=218495 GN=glgA PE=3 SV=1
C0M712	4.99e-281	1	475	1	475	Glycogen synthase OS=Streptococcus equi subsp. equi (strain 4047) OX=553482 GN=glgA PE=3 SV=1
C0MH77	2.03e-280	1	475	1	475	Glycogen synthase OS=Streptococcus equi subsp. zooepidemicus (strain H70) OX=553483 GN=glgA PE=3 SV=1
A8AYH0	1.12e-277	1	475	1	475	Glycogen synthase OS=Streptococcus gordonii (strain Challis / ATCC 35105 / BCRC 15272 / CH1 / DL1 / V288) OX=467705 GN=glgA PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000064	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000576_00354.