You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000000581_00940
You are here: Home > Sequence: MGYG000000581_00940
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Alphaproteobacteria; RF32; CAG-239; CAG-495; | |||||||||||
| CAZyme ID | MGYG000000581_00940 | |||||||||||
| CAZy Family | GH23 | |||||||||||
| CAZyme Description | Membrane-bound lytic murein transglycosylase C | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 26015; End: 27757 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH23 | 425 | 553 | 1.2e-23 | 0.7851851851851852 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd13401 | Slt70-like | 1.15e-52 | 409 | 558 | 1 | 152 | 70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda. |
| cd16896 | LT_Slt70-like | 2.20e-38 | 422 | 552 | 16 | 144 | uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
| cd00254 | LT-like | 2.46e-35 | 426 | 553 | 2 | 111 | lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
| COG0741 | MltE | 6.69e-28 | 283 | 568 | 7 | 296 | Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis]. |
| PRK11619 | PRK11619 | 2.73e-25 | 419 | 550 | 488 | 619 | lytic murein transglycosylase; Provisional |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QIM10634.1 | 3.49e-153 | 1 | 577 | 1 | 577 |
| AMW33857.1 | 2.36e-102 | 44 | 580 | 58 | 594 |
| AUG55166.1 | 2.02e-101 | 44 | 576 | 64 | 602 |
| AWY99815.1 | 1.85e-99 | 29 | 576 | 12 | 566 |
| QPO11317.1 | 1.94e-98 | 3 | 580 | 13 | 606 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1QSA_A | 8.59e-25 | 264 | 571 | 318 | 613 | CrystalStructure Of The 70 Kda Soluble Lytic Transglycosylase Slt70 From Escherichia Coli At 1.65 Angstroms Resolution [Escherichia coli],1QTE_A Crystal Structure Of The 70 Kda Soluble Lytic Transglycosylase Slt70 From Escherichia Coli At 1.90 A Resolution In Complex With A 1,6- Anhydromurotripeptide [Escherichia coli] |
| 1SLY_A | 1.51e-23 | 264 | 571 | 318 | 613 | ComplexOf The 70-Kda Soluble Lytic Transglycosylase With Bulgecin A [Escherichia coli] |
| 5O1J_A | 2.34e-23 | 227 | 568 | 238 | 572 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
| 5MPQ_A | 3.07e-23 | 227 | 568 | 234 | 568 | BulgecinA: The key to a broad-spectrum inhibitor that targets lytic transglycosylases [Neisseria meningitidis] |
| 6FPN_B | 3.19e-23 | 227 | 568 | 244 | 578 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P0AGC4 | 5.12e-24 | 264 | 571 | 345 | 640 | Soluble lytic murein transglycosylase OS=Escherichia coli O157:H7 OX=83334 GN=slt PE=3 SV=1 |
| P0AGC3 | 5.12e-24 | 264 | 571 | 345 | 640 | Soluble lytic murein transglycosylase OS=Escherichia coli (strain K12) OX=83333 GN=slt PE=1 SV=1 |
| P39434 | 2.03e-21 | 264 | 574 | 345 | 641 | Soluble lytic murein transglycosylase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=slt PE=3 SV=2 |
| O31608 | 6.94e-16 | 423 | 553 | 73 | 180 | Putative murein lytic transglycosylase YjbJ OS=Bacillus subtilis (strain 168) OX=224308 GN=yjbJ PE=3 SV=1 |
| O64046 | 1.26e-13 | 419 | 552 | 1431 | 1541 | Probable tape measure protein OS=Bacillus phage SPbeta OX=66797 GN=yomI PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000239 | 0.999164 | 0.000153 | 0.000146 | 0.000136 | 0.000129 |