You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000000588_01405
You are here: Home > Sequence: MGYG000000588_01405
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes; Bacilli; ML615J-28; CAG-313; UMGS75; | |||||||||||
| CAZyme ID | MGYG000000588_01405 | |||||||||||
| CAZy Family | GT11 | |||||||||||
| CAZyme Description | O-antigen biosynthesis glycosyltransferase WbnK | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 2730; End: 3599 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT11 | 4 | 285 | 1e-59 | 0.9818840579710145 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd11301 | Fut1_Fut2_like | 4.78e-46 | 2 | 284 | 3 | 262 | Alpha-1,2-fucosyltransferase. Alpha-1,2-fucosyltransferases (Fut1, Fut2) catalyze the transfer of alpha-L-fucose to the terminal beta-D-galactose residue of glycoconjugates via an alpha-1,2-linkage, generating carbohydrate structures that exhibit H-antigenicity for blood-group carbohydrates. These structures also act as ligands for morphogenesis, the adhesion of microbes, and metastasizing cancer cells. Fut1 is responsible for producing the H antigen on red blood cells. Fut2 is expressed in epithelia of secretory tissues, and individuals termed "secretors" have at least one functional copy of the gene; they secrete H antigen which is further processed into A and/or B antigens depending on the ABO genotype. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. |
| pfam01531 | Glyco_transf_11 | 4.22e-16 | 6 | 272 | 37 | 277 | Glycosyl transferase family 11. This family contains several fucosyl transferase enzymes. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AAG26470.1 | 2.37e-216 | 1 | 289 | 1 | 289 |
| BAD48584.1 | 2.37e-216 | 1 | 289 | 1 | 289 |
| CAH07600.1 | 2.37e-216 | 1 | 289 | 1 | 289 |
| QCT78417.1 | 2.37e-216 | 1 | 289 | 1 | 289 |
| CBW22399.1 | 3.38e-63 | 1 | 283 | 1 | 287 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q58YV9 | 5.24e-15 | 177 | 286 | 190 | 302 | O-antigen biosynthesis glycosyltransferase WbnK OS=Escherichia coli OX=562 GN=wbnK PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000058 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |