logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000000605_00176

You are here: Home > Sequence: MGYG000000605_00176

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Ruminococcus_C;
CAZyme ID MGYG000000605_00176
CAZy Family GH44
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
837 MGYG000000605_6|CGC1 91712.68 3.9874
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000605 2224694 MAG Madagascar Africa
Gene Location Start: 952;  End: 3465  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.4 3.2.1.151

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH44 39 549 9.5e-156 0.9902723735408561
CBM76 565 702 2.6e-30 0.9130434782608695

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam12891 Glyco_hydro_44 8.55e-67 94 327 1 233
Glycoside hydrolase family 44. This is a family of bacterial glycoside hydrolases formerly known as cellulase family J, and now known as Cel44A. It is one of the major enzymatic components of the cellulosome of Clostridium thermocellum strain F1 and of many other Firmicutes.
cd14256 Dockerin_I 8.61e-10 769 825 1 57
Type I dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type I dockerins, which are responsible for anchoring a variety of enzymatic domains to the complex.
cd14253 Dockerin 1.53e-05 770 825 1 56
Dockerin repeat domain. Dockerins are modules in the cellulosome complex that often anchor catalytic subunits by binding to cohesin domains of scaffolding proteins. Three types of dockerins and their corresponding cohesin have been described in the literature. This alignment models two consecutive dockerin repeats, the functional unit.
pfam00404 Dockerin_1 4.20e-05 770 825 1 56
Dockerin type I repeat. The dockerin repeat is the binding partner of the cohesin domain pfam00963. The cohesin-dockerin interaction is the crucial interaction for complex formation in the cellulosome. The dockerin repeats, each bearing homology to the EF-hand calcium-binding loop bind calcium.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ERJ96918.1 6.34e-292 1 832 12 861
CAC83072.1 1.06e-187 4 832 2 807
AAA95959.1 3.43e-179 4 611 2 593
CDD54427.1 8.16e-176 24 700 12 681
CBL16808.1 4.57e-175 37 700 31 681

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2E0P_A 5.43e-124 42 548 12 514
ChainA, Endoglucanase [Acetivibrio thermocellus],2E4T_A Chain A, Endoglucanase [Acetivibrio thermocellus],2EO7_A Chain A, Endoglucanase [Acetivibrio thermocellus]
2EEX_A 1.51e-123 42 548 12 514
ChainA, Endoglucanase [Acetivibrio thermocellus],2EJ1_A Chain A, Endoglucanase [Acetivibrio thermocellus],2EQD_A Chain A, Endoglucanase [Acetivibrio thermocellus]
3IK2_A 1.52e-118 39 548 2 509
CrystalStructure of a Glycoside Hydrolase Family 44 Endoglucanase produced by Clostridium acetobutylium ATCC 824 [Clostridium acetobutylicum ATCC 824]
2YIH_A 5.67e-117 40 549 10 516
Structureof a Paenibacillus polymyxa Xyloglucanase from GH family 44 with Xyloglucan [Paenibacillus polymyxa],2YJQ_A Structure of a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 [Paenibacillus polymyxa],2YJQ_B Structure of a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 [Paenibacillus polymyxa]
2YKK_A 1.21e-115 40 549 10 516
Structureof a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 [Paenibacillus polymyxa],3ZQ9_A Structure of a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 [Paenibacillus polymyxa]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P29719 1.16e-120 13 554 9 547
Endoglucanase A OS=Paenibacillus lautus OX=1401 GN=celA PE=3 SV=1
P22533 1.02e-111 42 539 790 1293
Beta-mannanase/endoglucanase A OS=Caldicellulosiruptor saccharolyticus OX=44001 GN=manA PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.007835 0.596251 0.394451 0.000702 0.000402 0.000337

TMHMM  Annotations      download full data without filtering help

start end
7 24