CAZyme Information: MGYG000000606_02384

Basic Information

• Species: RC9 sp000433355
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; UBA932; RC9; RC9 sp000433355
• CAZyme ID: MGYG000000606_02384
• CAZy Family: GT2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
471		53645.48	5.1673

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000606	3291011	MAG	Madagascar	Africa

• Gene Location: Start: 176; End: 1591 Strand: -

Full Sequence      

MNRIDCFVPFVSDEQVAVTAANLRAESEVAKVEFLDAAIFKSTTGIRKIAESAAAPFTMI
YTKTTELSFGQFALERFLSIAEDSSAAMVYADHFNEVDGNRAFAPVIDCQEGALRDDFDF
GSVLIYRTSALKEAVARMDVDYEYAGLYDLRLKVSQRGSLVHINEYLYYEIETDTRKSGE
KLFDYVDPKNRAVQIEMEKACTQHLKDVGGYLEPKFKHIEFSDNSFEYEASVVIPCKNRV
RTIGDALTSALNQKTTFKYNVIVVDDNSTDGTVDVIKKFIDDPKLVYIAQDKSYHAIGGN
WNAALHHPKCGKFAIQLDSDDVYYDENTVQKFVDAFYAQNCAMVVGTYRMTNFQMETLPP
GIIDHREWTPENGRNNALRINGLGAPRGFYVPMLRTINFPTTKYGEDYAVGLRVSREYQI
GRIYDVVYNCRRWDDNSDASLDIDKVNANNLYKDRIRTWELQARIKMNKKS

Enzyme Prediction     

No EC number prediction in MGYG000000606_02384.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	231	353	1.4e-24	0.7058823529411765

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam00535	Glycos_transf_2	5.41e-20	231	397	1	163	Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.
cd00761	Glyco_tranf_GTA_type	1.09e-17	232	350	1	117	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.
cd06433	GT_2_WfgS_like	1.02e-14	231	350	1	115	WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
COG0463	WcaA	1.89e-14	231	326	6	99	Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].
cd02525	Succinoglycan_BP_ExoA	1.05e-13	231	361	3	124	ExoA is involved in the biosynthesis of succinoglycan. Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AGY52991.1	4.46e-236	2	469	3	485
QIK55484.1	3.10e-224	3	471	4	487
QIK60901.1	8.85e-224	3	471	4	487
QPH58388.1	2.67e-220	1	470	1	485
BBK86005.1	7.64e-220	1	469	1	484

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000070	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000606_02384.