dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000000608_00787

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Species

Lineage

Bacteria; Verrucomicrobiota; Lentisphaeria; Victivallales; Victivallaceae; UMGS1518;

CAZyme ID

MGYG000000608_00787

CAZy Family

GH89

CAZyme Description

hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
717		82454.33	4.8233

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000608	2613041	MAG	Madagascar	Africa

Gene Location

Start: 5; End: 2158 Strand: +

No EC number prediction in MGYG000000608_00787.

Family	Start	End	Evalue	family coverage
GH89	2	566	3.8e-175	0.8461538461538461

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam05089	NAGLU	3.07e-152	2	342	8	333	Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This central domain has a tim barrel fold.
pfam12972	NAGLU_C	1.13e-48	350	586	1	258	Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This C-terminal domain has an all alpha helical fold.

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QAA56418.1	1.03e-249	1	717	134	847
QAR50239.1	1.03e-249	1	717	134	847
QWO98456.1	1.03e-249	1	717	134	847
QAA54104.1	1.03e-249	1	717	134	847
QAA58727.1	1.03e-249	1	717	134	847

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4XWH_A	8.99e-99	2	563	114	671	Crystalstructure of the human N-acetyl-alpha-glucosaminidase [Homo sapiens]
2VC9_A	1.61e-54	2	548	277	822	Family89 Glycoside Hydrolase from Clostridium perfringens in complex with 2-acetamido-1,2-dideoxynojirmycin [Clostridium perfringens],2VCA_A Family 89 glycoside hydrolase from Clostridium perfringens in complex with beta-N-acetyl-D-glucosamine [Clostridium perfringens],2VCB_A Family 89 Glycoside Hydrolase from Clostridium perfringens in complex with PUGNAc [Clostridium perfringens],2VCC_A Family 89 Glycoside Hydrolase from Clostridium perfringens [Clostridium perfringens]
7MFK_A	1.70e-54	2	548	285	830	ChainA, Alpha-N-acetylglucosaminidase family protein [Clostridium perfringens ATCC 13124],7MFL_A Chain A, Alpha-N-acetylglucosaminidase family protein [Clostridium perfringens ATCC 13124]
4A4A_A	1.15e-53	2	548	300	845	CpGH89(E483Q, E601Q), from Clostridium perfringens, in complex with its substrate GlcNAc-alpha-1,4-galactose [Clostridium perfringens]

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P54802	8.42e-98	2	563	137	694	Alpha-N-acetylglucosaminidase OS=Homo sapiens OX=9606 GN=NAGLU PE=1 SV=2
Q9FNA3	7.56e-92	1	586	163	798	Alpha-N-acetylglucosaminidase OS=Arabidopsis thaliana OX=3702 GN=NAGLU PE=2 SV=1

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000058	0.000000	0.000000	0.000000	0.000000	0.000000

There is no transmembrane helices in MGYG000000608_00787.