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CAZyme Information: MGYG000000612_01284

You are here: Home > Sequence: MGYG000000612_01284

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes_C; Negativicutes; Veillonellales; Megasphaeraceae; Megasphaera;
CAZyme ID MGYG000000612_01284
CAZy Family CE11
CAZyme Description UDP-3-O-acyl-N-acetylglucosamine deacetylase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
277 30591.26 6.0727
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000612 1970930 MAG Madagascar Africa
Gene Location Start: 1581;  End: 2414  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000612_01284.

CAZyme Signature Domains help

Family Start End Evalue family coverage
CE11 6 273 2.9e-96 0.992619926199262

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam03331 LpxC 6.78e-130 6 274 1 271
UDP-3-O-acyl N-acetylglycosamine deacetylase. The enzymes in this family catalyze the second step in the biosynthetic pathway for lipid A.
PRK13186 lpxC 1.41e-117 6 275 4 275
UDP-3-O-acyl-N-acetylglucosamine deacetylase.
COG0774 LpxC 4.52e-104 6 274 4 277
UDP-3-O-acyl-N-acetylglucosamine deacetylase [Cell wall/membrane/envelope biogenesis].
PRK13188 PRK13188 1.29e-83 6 277 5 303
bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Reviewed
TIGR00325 lpxC 2.32e-83 4 272 1 271
UDP-3-0-acyl N-acetylglucosamine deacetylase. UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc deacetylase from E. coli , LpxC, was previously designated EnvA. This enzyme is involved in lipid-A precursor biosynthesis. It is essential for cell viability. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AVO26609.1 9.00e-190 1 277 1 277
CCC72319.1 9.00e-190 1 277 1 277
ALG41190.1 9.00e-190 1 277 1 277
AVO73787.1 9.00e-190 1 277 1 277
AXL21688.1 1.46e-163 1 276 1 276

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5UPG_A 4.79e-70 2 275 1 278
Crystalstructure of LpxC from Pseudomonas aeruginosa in complex with PF-5081090 [Pseudomonas aeruginosa PAO1],6C9C_A Crystal structure of LpxC from Pseudomonas aeruginosa in complex with racemic ligand PT803 [Pseudomonas aeruginosa UCBPP-PA14],6CAX_A Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PT805 [Pseudomonas aeruginosa],6DUI_A Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PT801 [Pseudomonas aeruginosa LESB58],6E54_A Crystal structure of LpxC from Pseudomonas aeruginosa in complex with ligand PT802 [Pseudomonas aeruginosa PAO1]
5N8C_A 6.77e-70 2 275 1 278
Crystalstructure of Pseudomonas aeruginosa LpxC complexed with inhibitor [Pseudomonas aeruginosa],5N8C_B Crystal structure of Pseudomonas aeruginosa LpxC complexed with inhibitor [Pseudomonas aeruginosa]
5U39_A 1.03e-69 2 275 2 279
Pseudomonasaeruginosa LpxC in complex with CHIR-090 [Pseudomonas aeruginosa PAO1]
4J3D_A 1.55e-69 3 275 1 277
Pseudomonasaeruginosa LpxC in complex with a hydroxamate inhibitor [Pseudomonas aeruginosa PAO1],4J3D_B Pseudomonas aeruginosa LpxC in complex with a hydroxamate inhibitor [Pseudomonas aeruginosa PAO1]
5U3B_A 1.65e-69 3 275 1 277
Pseudomonasaeruginosa LpxC in complex with NVS-LPXC-01 [Pseudomonas aeruginosa PAO1],5U3B_B Pseudomonas aeruginosa LpxC in complex with NVS-LPXC-01 [Pseudomonas aeruginosa PAO1],6MAE_A CHAIN A. UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase PA-LPXC Complexed with (R)-3-((S)-3-(4-(cyclopropylethynyl)phenyl)-2-oxooxazolidin-5-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)propenamide [Pseudomonas aeruginosa PAO1]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q2S9Z8 8.45e-73 3 275 1 277
UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Hahella chejuensis (strain KCTC 2396) OX=349521 GN=lpxC PE=3 SV=1
Q1I5C4 6.99e-72 3 275 1 277
UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Pseudomonas entomophila (strain L48) OX=384676 GN=lpxC PE=3 SV=1
C5BP28 2.80e-71 3 274 1 276
UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Teredinibacter turnerae (strain ATCC 39867 / T7901) OX=377629 GN=lpxC PE=3 SV=1
Q1D2K0 7.80e-71 6 275 8 279
UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Myxococcus xanthus (strain DK1622) OX=246197 GN=lpxC PE=3 SV=1
A1U3F2 1.16e-70 3 275 1 277
UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Marinobacter nauticus (strain ATCC 700491 / DSM 11845 / VT8) OX=351348 GN=lpxC PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.999008 0.001031 0.000004 0.000002 0.000001 0.000002

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000612_01284.