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CAZyme Information: MGYG000000616_00700
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Actinobacteriota; Coriobacteriia; Coriobacteriales; Eggerthellaceae; CAG-1427; | |||||||||||
| CAZyme ID | MGYG000000616_00700 | |||||||||||
| CAZy Family | GT2 | |||||||||||
| CAZyme Description | Galactofuranosyltransferase GlfT2 | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 24985; End: 26871 Strand: + | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd04185 | GT_2_like_b | 8.37e-13 | 202 | 417 | 25 | 202 | Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families. |
| COG1216 | GT2 | 2.54e-12 | 192 | 420 | 23 | 240 | Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism]. |
| pfam13641 | Glyco_tranf_2_3 | 8.34e-10 | 203 | 381 | 31 | 195 | Glycosyltransferase like family 2. Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis. |
| cd02526 | GT2_RfbF_like | 4.58e-08 | 184 | 381 | 8 | 187 | RfbF is a putative dTDP-rhamnosyl transferase. Shigella flexneri RfbF protein is a putative dTDP-rhamnosyl transferase. dTDP rhamnosyl transferases of Shigella flexneri add rhamnose sugars to N-acetyl-glucosamine in the O-antigen tetrasaccharide repeat. Lipopolysaccharide O antigens are important virulence determinants for many bacteria. The variations of sugar composition, the sequence of the sugars and the linkages in the O antigen provide structural diversity of the O antigen. |
| pfam17994 | Glft2_N | 0.003 | 8 | 81 | 1 | 79 | Galactofuranosyltransferase 2 N-terminal. This is the N-terminal beta-barrel domain found in the polymerizing galactofuranosyltransferase GlfT2 (Rv3808c). This enzyme synthesizes the bulk of the galactan portion of the mycolyl-arabinogalactan complex, which is the largest component of the mycobacterial cell wall such as in Mycobacterium tuberculosis. The N-terminal domain contains two short helices preceding a 10-stranded beta-sandwich with jelly roll topology. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| BAK44118.1 | 6.18e-233 | 4 | 623 | 2 | 619 |
| BBH50146.1 | 4.14e-179 | 4 | 622 | 2 | 612 |
| QUC02092.1 | 3.07e-175 | 4 | 626 | 2 | 617 |
| AEB07220.1 | 8.01e-124 | 9 | 620 | 7 | 623 |
| QUC04258.1 | 2.04e-119 | 46 | 623 | 47 | 635 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 4FIX_A | 4.28e-30 | 8 | 620 | 29 | 646 | CrystalStructure of GlfT2 [Mycobacterium tuberculosis H37Rv],4FIX_B Crystal Structure of GlfT2 [Mycobacterium tuberculosis H37Rv],4FIY_A Crystal Structure of GlfT2 Complexed with UDP [Mycobacterium tuberculosis H37Rv],4FIY_B Crystal Structure of GlfT2 Complexed with UDP [Mycobacterium tuberculosis H37Rv] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| A0R628 | 6.55e-32 | 8 | 620 | 20 | 636 | Galactofuranosyltransferase GlfT2 OS=Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) OX=246196 GN=glfT2 PE=3 SV=1 |
| O53585 | 2.14e-29 | 8 | 620 | 9 | 626 | Galactofuranosyltransferase GlfT2 OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=glfT2 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000047 | 0.000002 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |