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CAZyme Information: MGYG000000623_00340

You are here: Home > Sequence: MGYG000000623_00340

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Blautia_A sp900763175
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Blautia_A; Blautia_A sp900763175
CAZyme ID MGYG000000623_00340
CAZy Family GH25
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
525 MGYG000000623_6|CGC1 58898.97 9.6526
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000623 3121730 MAG Madagascar Africa
Gene Location Start: 11875;  End: 13452  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000623_00340.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH25 88 266 4.3e-44 0.9943502824858758

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd06414 GH25_LytC-like 1.02e-49 86 288 2 191
The LytC lysozyme of Streptococcus pneumoniae is a bacterial cell wall hydrolase that cleaves the beta1-4-glycosydic bond located between the N-acetylmuramoyl-N-glucosaminyl residues of the cell wall polysaccharide chains. LytC is composed of a C-terminal glycosyl hydrolase family 25 (GH25) domain and an N-terminal choline-binding module (CBM) consisting of eleven homologous repeats that specifically recognizes the choline residues of pneumococcal lipoteichoic and teichoic acids. This domain arrangement is the reverse of the major pneumococcal autolysin, LytA, and the CPL-1-like lytic enzymes of the pneumococcal bacteriophages, in which the CBM (consisting of six repeats) is at the C-terminus. This model represents the C-terminal catalytic domain of the LytC-like enzymes.
pfam01183 Glyco_hydro_25 1.50e-20 89 265 2 179
Glycosyl hydrolases family 25.
cd00599 GH25_muramidase 3.94e-19 86 285 1 184
Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. This family of muramidases contains a glycosyl hydrolase family 25 (GH25) catalytic domain and is found in bacteria, fungi, slime molds, round worms, protozoans and bacteriophages. The bacteriophage members are referred to as endolysins which are involved in lysing the host cell at the end of the replication cycle to allow release of mature phage particles. Endolysins are typically modular enzymes consisting of a catalytically active domain that hydrolyzes the peptidoglycan cell wall and a cell wall-binding domain that anchors the protein to the cell wall. Endolysins generally have narrow substrate specificities with either intra-species or intra-genus bacteriolytic activity.
cd06524 GH25_YegX-like 5.77e-17 86 285 1 190
YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins.
cd06413 GH25_muramidase_1 6.99e-16 85 285 3 187
Uncharacterized bacterial muramidase containing a glycosyl hydrolase family 25 (GH25) catalytic domain. Endo-N-acetylmuramidases are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QCU01355.1 3.72e-157 1 518 1 506
CBL21600.1 6.89e-65 1 203 1 200
ASM68843.1 3.13e-55 62 310 71 308
QQR03194.1 4.31e-41 13 340 16 311
ANU47907.1 4.31e-41 13 340 16 311

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3HMC_A 2.44e-10 88 266 8 171
Endolysinfrom Bacillus anthracis [Bacillus anthracis]
2G7C_A 1.70e-06 352 516 70 248
ChainA, Toxin A [Clostridioides difficile],2G7C_B Chain B, Toxin A [Clostridioides difficile]
4NC0_A 1.71e-06 352 516 72 250
ChainA, Cell wall-binding repeat protein [Clostridioides difficile NAP07]
4NBY_A 1.78e-06 352 516 77 255
ChainA, Cell wall-binding repeat protein [Clostridioides difficile NAP07],4NC1_A Chain A, Cell wall-binding repeat protein [Clostridioides difficile NAP07],4NC1_B Chain B, Cell wall-binding repeat protein [Clostridioides difficile NAP07]
5UMI_C 8.13e-06 352 516 86 264
ChainC, Toxin A [Clostridioides difficile]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P76421 9.02e-10 87 266 69 245
Uncharacterized protein YegX OS=Escherichia coli (strain K12) OX=83333 GN=yegX PE=3 SV=2
Q8FFY2 1.21e-09 87 266 69 245
Uncharacterized protein YegX OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) OX=199310 GN=yegX PE=3 SV=2
Q8X7H0 3.94e-09 87 266 69 245
Uncharacterized protein YegX OS=Escherichia coli O157:H7 OX=83334 GN=yegX PE=3 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000296 0.999053 0.000160 0.000182 0.000148 0.000133

TMHMM  Annotations      download full data without filtering help

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